ChaoLiang科研成果

Home People Research Research Publications Teaching Protocol Sharing News Center for Pain Medicine Research Brief Info Software Alumni Join us Contact us Chao Liang Department of Biology Dr. Chao Liang obtained Ph.D. degree from Hong Kong Baptist University in 2016. After graduation, he worked as Post-doctoral Research Fellow and Research Assistant Professor in Hong Kong Baptist University. Since 2020, Dr. Chao Liang was employed as Associate Professor in Department of Biology, Southern University of Science and Technology. Dr. Chao Liang focuses on mechanistic studies, translational medicine and precision medicine in bone & joint diseases and tumors. Personal Profile Personal Profile Research ◆ Mechanistic studies in bone & joint diseases and tumors ◆ Translational medicine in bone & joint diseases and tumors ◆ Precision medicine in bone & joint diseases and tumors Teaching Genetic Engineering Publications Read More 1.Liang C*, Guo B, Wu H, Shao N, Li D, Liu J, Dang L, Wang C, Li H, Li S, Lau WK, Cao Y, Yang Z, Lu C, He X, Au DW, Pan X, Zhang BT, Lu C, Zhang H, Yue K, Qian A, Shang P, Xu J, Xiao L, Bian Z, Tan W, Liang Z, He F, Zhang L, Lu A, Zhang G. Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy. Nat Med. 2015 Mar;21(3):288-94. doi: 10.1038/nm.3791. 2.Liang C*, Peng S, Li J, Lu J, Guan D, Jiang F, Lu C, Li F, He X, Zhu H, Au DWT, Yang D, Zhang BT, Lu A, Zhang G. Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis. Nat Commun. 2018 Aug 24;9(1):3428. doi: 10.1038/s41467-018-05974-z. 3.Liang C*#, Li J, Lu C, Xie D, Liu J, Zhong C, Wu X, Dai R, Zhang H, Guan D, Guo B, He B, Li F, He X, Zhang W, Zhang BT, Zhang G, Lu A. HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis. Nat Commun. 2019 Oct 8;10(1):4579. doi: 10.1038/s41467-019-12163-z. 4.Liang C*#, Li F, Wang L, Zhang ZK, Wang C, He B, Li J, Chen Z, Shaikh AB, Liu J, Wu X, Peng S, Dang L, Guo B, He X, Au DWT, Lu C, Zhu H, Zhang BT, Lu A, Zhang G. Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma. Biomaterials. 2017 Sep 13;147:68-85. doi: 10.1016/j.biomaterials.2017.09.015. 5.Li F, Lu J, Liu J, Liang C*, Wang M, Wang L, Li D, Yao H, Zhang Q, Wen J, Zhang ZK, Li J, Lv Q, He X, Guo B, Guan D, Yu Y, Dang L, Wu X, Li Y, Chen G, Jiang F, Sun S, Zhang BT, Lu A, Zhang G. A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer. Nat Commun. 2017 Nov 9;8(1):1390. doi: 10.1038/s41467-017-01565-6. People Read More PrevNext UpDown Join us Read More Contact Us Contact Address Room 309, No. 1 Scientific Research Building, Southern University of Science and Technology, No.1088 Xueyuan road, Taoyuan Street, Nanshan District,Shenzhen,Guangdong Office Phone Email liangc@sustech.edu.cn

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