王磊科研成果

基本信息 科学研究 RESEARCHES 个人新闻 / News 论文著作 PUBLICATIONS 授权专利代表作 新建主栏目 个人信息 PERSONAL INFORMATION 名称 基本信息/ Personal Information 王磊，欧盟玛丽居里学者，黑龙江省高层次人才，黑龙江省优秀青年基金获得者，哈尔滨工业大学化工与化学学院国际发展中心主任，高分子科学与工程系研究员，博士生导师；国际仿生工程学会会员，中国复合材料学会高级会员，中国微米纳米技术学会高级会员，中国化学会会员。 主持及完成国家重点研发计划、国家自然科学基金青年项目/面上项目、国家部委项目（2项）、黑龙江省自然科学基金优秀青年基金项目/面上项目、中国博士后特别资助（站中）、中国博士后面上项目（一等资助）等国家级、省市级课题研究30余项，参与完成国家自然科学基金面上项目5项、黑龙江省重大成果转化项目（1项）。 目前主要研究方向为仿生材料的设计和构建及其在生物传感器、生物能源、人工细胞和微纳米马达领域的应用。拟解决的关键科学问题在于设计和构建微纳米尺度下具有运动行为的人工细胞模型，为深入探索疾病诊疗和病理分析、细胞内能量再生以及细胞与周边环境的相互作用等前沿课题提供基础。迄今在 Angew. Chem. Int. Ed., Sci. Robotics, Nat. Commun., Adv. Funct. Mater., Small, Lab Chip, ACS Nano, Anal. Chem.,等国际和国内高水平杂志上发表了100余篇高影响力论文，其中通讯作者（含第一作者）论文50余篇。所有文章中影响因子大于10的40余篇；论文总引次数超过3500次，申请国家发明专利14项，其中已有6项获得授权。 目前担任国家自然科学基金函评专家，哈尔滨市、深圳市自然科学基金评审专家，Frontiers in Chem.杂志副主编、BMEMat杂志青年编委；同时担任Chem. Asian J., Chin. J. Anal. Chem. 等多个国内外杂志客座主编，以及Nat. Commun., Angew. Chem. Int. Ed., ACS Nano, Small, ACS Applied Materials & Interfaces, Lab Chip, ACS Biomaterial Science & Engineering, European Polymer Journal, International Biodeterioration & Biodegradation等国内外杂志特邀审稿人。 Lei Wang, Marie Curie Fellow (EU), Professor, School of Chemistry & Chemical Engineering, Harbin Institute of Technology, China. He participated in 30 funding programs, including 7 from the National Natural Science Foundation of China. The KEY problem to be solved in the group is the construction of motile artificial cells or bacteria towards the application in biomimicry and biomedical fields. So far, he has published more than 100 peer-reviewed papers in high-level international journals, including Angew. Chem. Int. Ed., Sci. Robotics, Nat. Commun., Adv. Funct. Mater., Small, Lab Chip, ACS Nano, Anal. Chem., which have been cited more than 3000 times. He also applied 14 national invention patents, six of which have been authorized. He also serves as the Associate Editor for Frontiers in Chemistry (Nanoscience), Young editorial board member of BMEMat, and invited reviewer for Nat. Commun., Angew. Chem. Int. Ed., ACS Nano, SMALL, ACS Applied Materials & Interfaces, Lab Chip, ACS Biomaterial Science & Engineering, European Polymer Journal, International Biodeterioration & Biodegradation etc. He also serves as board member or guest editors for several journals, such as Chem. Asian J., Chin. J. Anal. Chem, Frontiers in Chem., Nanomaterials, etc. 工作经历 / Working Experience 2023.09-至今 国际发展中心主任 2023.02-至今 研究员，哈工大先进技术研究院 2021.04-至今 博士生导师，哈尔滨工业大学化工与化学学院 2020.01-至今 副教授（准聘），哈尔滨工业大学化工与化学学院 2017.12-2019.12 欧盟玛丽居里学者，西班牙生物工程研究所（IBEC, Spain） 合作导师 Prof. Samuel Sanchez, https://ibecbarcelona.eu/nanodevices 2016.03-2020.01 讲师，博士后，硕士生导师，哈尔滨工业大学材料学院 合作导师 耿林教授 http://homepage.hit.edu.cn/genglin 2015.08-2016.02 助教/博士后，哈尔滨工业大学化工与化学学院 合作导师 黄鑫教授 http://homepage.hit.edu.cn/huangxin 2023.02-Now Professor, Ph.D Supervisor, School of Chemistry & Chemical Engineering, HIT 2017.12-2019.12 Marie Curie Fellow, Institute of Bioengineering, Spain. Collobrated advisor: Prof. Samuel Sanchez, https://ibecbarcelona.eu/nanodevices 2016.03-2020.01 Assistant Professor, School of Material Science & Engineering, HIT Collobrated advisor: Prof. Lin Geng http://homepage.hit.edu.cn/genglin 2015.08-2016.02 Postdoc Research fellow, School of Chemistry & Chemical Engineering, HIT Collobrated advisor: Prof. Xin Huang, http://homepage.hit.edu.cn/huangxin 教育经历 / Education Background 2004.09-2008.06 QUST, Bachelor, Supervisor: Prof. Guangming Nie （聂广明 教授） 2008.09-2011.06 QUST, Master, Supervisor: Prof. Shusheng Zhang（张书圣 教授，国家杰青）& Prof. Guifen Jie （接贵芬 教授） Research area: Electrochemiluminescence; 2011.09-2015.07 HIT, Ph.D., Supervisor: Prof. Xiaojun Han（韩晓军 教授，国家级人才） Research area: Self-assembly of biomaterials & Microfluidics 2012.12-2013.12 University of Maryland, USA (美国马里兰大学) Joint Ph. D, Supervisor: Prof. Zhihong Nie （聂志鸿 教授，国家杰青）, http://www2.chem.umd.edu/groups/znie/ https://www.nielab.com/ 2014.07-2014.12 University of Leeds, UK (英国利兹大学) Joint Ph. D student, Supervisor: Prof. S. D. Evans http://www.mnp.leeds.ac.uk/steve-evans.html 研究领域 / Research Areas 名称 主要研究方向：仿生材料在生物传感器、生物能源、微纳米马达和功能化原细胞模拟中的应用。 Main research interest: Design of biosensors, fabrication of micromotors, and preparation of functional protocells towards bioenergy or biomedical applications based on the self-assembly of biomimetic materials. 目前开展的具体方向： 1，微纳米尺度人工细胞模型（微纳米机器人）的设计、构建以及其在生命医学和绿色能源领域的应用探索； 2，高灵敏生物/气体传感器的设计、构建、优化以及应用于疾病诊疗等领域； 3，基于生物大分子设计仿生材料并模拟生物功能，探索其在绿色能源和环境修复领域的应用。 国内外合作 / Collaboration 名称 美国马里兰大学 University of Maryland, USA 复旦大学 Fudan University, China 聂志鸿教授，Prof. Zhihong Nie, http://www2.chem.umd.edu/groups/znie/ Currently moved to Fudan University: https://www.nielab.com/research 美国康尼迪格大学 University of Connecticut, USA 何杰教授，Prof. Jie He, http://jiehe.lab.uconn.edu/ 四川大学 Sichuan University 刘犇教授，Prof. Ben Liu, http://hky.njnu.edu.cn/info/1072/3808.htm 哈尔滨工业大学 Harbin Institute of Technology 马星教授， Prof. Xing Ma, http://faculty.hitsz.edu.cn/maxing 吉林大学 Jilin University 杨扬教授，Prof. Yang Yang, http://chem.jlu.edu.cn/info/1121/10886.htm 德国马克普朗克研究所/西班牙生物工程研究所 Institute of Bioengineering Catalonia, Spain/ Max Planck Institute of Intelligent system, Germany Prof. S. Sanchez, http://www.is.mpg.de/sanchez http://www.ibecbarcelona.eu/nanodevices 英国利兹大学 University of Leeds, UK Prof. S. Evans, http://www.mnp.leeds.ac.uk/steve-evans.html 硕博招生信息 名称 博士招生名额：每年1~3名，择优录取； 硕士招生名额：每年1~2名，择优录取。 欢迎有志于未来开展科研工作的同学加入，我将尽自己所能地指导和帮助你，你未来的成功就是老师最开心的事情！ 招生方向，主要围绕“3 Bio”： 1，Biomimicry：微纳米人工细胞的设计、构建以及其在生命医学和绿色能源领域的应用探索； 2，Biosensor：高灵敏生物/气体传感器的设计、构建、优化以及应用于疾病诊疗等领域； 3，Bioenergy：基于生物大分子材料设计并模拟生物功能，探索其在绿色能源和环境修复领域的应用。 荣誉称号 / Honors & Fellowships 奖项名称 硕士研究生优秀毕业论文指导教师 获奖时间 2022-06 完成人 王磊，李宏凯 所获奖项 哈尔滨工业大学硕士研究生优秀毕业论文指导教师 简单介绍 祝贺宏凯获得哈工大2022届硕士研究生优秀毕业论文！！！ Well Done！！！ 奖项名称 欧盟玛丽居里项目资助 获奖时间 2017年 完成人 王磊 所获奖项 欧盟玛丽居里学者荣誉称号 简单介绍 奖项名称 博士生国家奖学金 获奖时间 2013年11月 完成人 王磊 所获奖项 博士生国家奖学金 简单介绍 奖项名称 国家留学基金委短期访学基金 获奖时间 2013年8月 完成人 所获奖项 简单介绍 奖项名称 Short-term visiting programme from CSC 获奖时间 Aug. 2013 完成人 所获奖项 简单介绍 奖项名称 National scholarship for Ph.D student 获奖时间 Nov. 2013 完成人 所获奖项 简单介绍 奖项名称 Marie Curie Fellowship 获奖时间 2017 完成人 所获奖项 简单介绍 讲授课程/ Lectures 名称 Biomedical polymers （生物医用高分子）for undergraduates in each fall semester. Applied techniques of functional polymers（实用功能高分子技术） for master students in each spring semester. 毕业学生信息 名称 指导的硕士毕业生： 2018级硕士 孙照玲 目前就职于理想汽车有限公司，研发岗位。 2019级硕士 黄勇维 目前就职于大庆市政府，公务员。 2020级硕士 陈思宇 目前就职于华为技术有限公司，研发岗位。 2020级硕士 李宏凯 （哈工大优秀硕士毕业论文获得者），目前就职于宝洁公司，研发岗位。 2021级硕士 吴文璐 目前就职于宁德时代新能源科技股份有限公司。 协助指导的博士毕业生： 2021级博士 陈海旭 目前就职于哈尔滨工业大学，博士后。 2021级博士 林幼萍 目前就职于哈尔滨工业大学，博士后。 科研项目/ Projects 项目名称 新型仿生膜体系的制备和应用研究 项目来源 国家自然科学基金面上项目 开始时间 结束时间 项目经费 80万元 担任角色 参与 项目类别 纵向项目 项目状态 完成 简单介绍 项目名称 具有运动行为的Janus人工细胞的构建与研究 项目来源 国家自然科学基金青年项目 开始时间 2018.01 结束时间 2020.12 项目经费 担任角色 负责 项目类别 纵向项目 项目状态 完成 简单介绍 学术会议和邀请报告/Conferences & Invited Talks 名称 Oct. 13-17, 2023, National Symposium on Polymers, Wuhan. (2023年10月，全国高分子学术论文报告会，武汉。) Oct. 12-15, 2023, ICBE, Wuhan. (2023年10月，第七届国际仿生工程学术会议，武汉。) Sep. 22-24, International Conference on Biomedical Materials, Nanjing. (2023年9月22日-24日，生物医用材料国际会议，南京。) Aug. 11-13, 2023, The first conference of Editorial Committee of BMEMat Journal and Academic Seminar, Jinan. (2023年8月，BMEMat杂志第一届编委会暨学术讨论会，济南。) Jun. 18, 2023, The 33rd CCS Congress, Qingdao. Oral talk on "The motility behavior of micro/nano artificial cells". (2023年6月，中国化学会第33届年会，青岛，仿生材料分会场。口头报告：微纳尺度人工细胞的运动行为研究) Dec. 14, 2021, CSMBT2021, 23rd Congress, Online oral talk on "Enzyme-powered artificial swimmers towards environmental applications." (2021年12月，中国微纳米协会第23节学术年会，微纳米马达分会场，在线报告：生物酶驱动的微纳米马达在环境领域的应用探索。) Sep.2021, IWBE 2021, Manchester. Online talk on "Biomimicry of cellular motility behavior". (2021年9月， 国际仿生工程研讨会，曼彻斯特。在线报告：细胞的运动行为模拟) Jul. 2021, IYCBSE 2021 Congress, Shenzhen. Invited talk on "Enzyme-powered Artifical cells". (2021年7月，国际仿生科学与工程青年论坛，深圳。邀请在线报告：生物酶驱动的人工细胞) Apr. 2021, The 32nd CCS Congress, Zhuhai. Oral talk on "Multifunctional Enzyme-powered Artifical cells". (2021年4月，中国化学会第32届年会，珠海。口头报告：细胞的运动行为模拟) Apr. 2021, The 6th Forum for Young Scientists, Nanjing. Invited talk on "Applications of Enzyme-powered Nanomotors". (2021年4月，第六届青年科学家论坛。邀请报告：生物酶驱动微纳米马达的应用) Oct. 2020, The Conference on Micro/nanotechnology for Medical Innovations, Xiamen. Invited talk on 'Lipase powered nanomotors towards bioapplications'. (2020年10月，第四届微米纳米技术应用创新大会，厦门。邀请报告：脂肪酶马达在生物医药领域的应用探索。) Oct. 2019, University of Alcala, Spain. Invited Talk on 'ECL biosensors for cytosensing'. (2019年10月，西班牙阿尔卡拉大学，Dr. Beatriz J. Sanchez's group.) Oct. 2019, Complutense University of Madrid, Spain. Invited Talk on 'Lipase-based bacterial models' Aug. 2019, ICMNM, Harbin, China. Invited Oral presentation on 'Novel protocell/bacterial models based on lipase', BEST ORAL PRESENTATION AWARD for Young Scientists (4 out of 33); (2019年8月， 中国工程院采油工程国际工程科技战略高端论坛暨第二届微纳米机器国际会议(ICMNM)，邀请报告：脂肪酶驱动的人工细胞和细菌模型。) Aug. 2019, Xiamen University, China. Invited Talk on 'Self-assembly of biomolecules towards biomimicry'. (2019年8月，厦门大学，鄢晓晖教授课题组。邀请报告:生物材料自组装在仿生材料设计中的应用。) Jul. 2019, MML 2019, Dresden, Germany. Oral presentation on 'Lipase based protocell models'. Jul. 2019, 12th IBEC Symposium, Poster on 'Natural proteinosome based soft robotics'. Jul. 2019, 2nd IBEC-ICMS Joint Symposium, Poster on 'Proteinosome based soft motors towards the protocell mimicry'. May. 2019, NanoSpain, Barcelona, Spain. Oral presentation on 'lipase powered nanomotors for oil degradation'. Sep. 2016, SIPCD, Suzhou, China, Poster presentation on 'single-step assembly for micromotors for controlled drug delivery'. BEST POSTER AWARD (8 out of 200). 个人新闻 / News 新闻标题 热烈祝贺课题组杨海跃同学获得硕士生国家奖学金！ 发布时间 2023-10-19 Congratulations to Haiyue for the National Award for Master Students!!! Well Done!!! 新闻标题 Congratulations to Dr. Lei Wang for obtaining the Best Poster Award at 2016 SIPCD! 发布时间 Sep. 2016 Congratulations to Dr. Lei Wang for obtaining the Best Poster Award at 2016 SIPCD! The details can be seen from the following link: https://twitter.com/Biomac_ACS 新闻标题 Jiaqiang, Weiran, Zibo and Yuxiong joined our group for conducting the innovation experiments!!! Welcome~ 发布时间 Dec.01, 2016 Jiaqiang, Weiran, Zibo and Yuxiong joined our group for conducting the innovation experiments!!! Welcome~ Their research topic would be the fabrication of microfibers using microfluidics. 新闻标题 Congratulations to Dr. Wang for the Chem. Commun paper！ 发布时间 2017-07-07 Our paper on ''Single-step fabrication of multi-compartmentalized biphasic proteinosomes'' is accepted for publication in Chem. Commun. !!! Congratulations to Lei and all the coauthors!!! http://pubs.rsc.org/en/content/articlelanding/2017/cc/c7cc04180b#!divAbstract 新闻标题 Dr. Wang attended the 2017 International Conference on Micro/Nano Machines, at Wuhan. 发布时间 2017-08-25 新闻标题 Dr. Wang obtained the Marie Curie fellowship from EU. 发布时间 2017-11-01 Dr. Wang successfully arrived at the Bio-nanodevices Group, led by Prof. S. Sanchez, with the Marie Curie fellowship supporting on the project of Protein-based micromotors. 新闻标题 Congratulations to Dr. Wang for the Anal. Chem. paper！ 发布时间 2018-08-21 Our paper was accepted for publication in Anal. Chem. Congratulations to Lei and all the coauthors!!! Signal-On Electrochemiluminescence of Self-Ordered Molybdenum Oxynitride Nanotube Arrays for Label-Free Cytosensing L. Wang, D.Q. Liu, Y. Sun, J.J. Su, B.W. Jin, L. Geng, Y.-Y. Song*, X. Huang*, and M. Yang* Anal. Chem., 2018, DOI: 10.1021/acs.analchem.8b02196. (IF=6.042) 新闻标题 Congrats to Dr. Wang for the paper published on Angew. Chem.! 发布时间 2018-11-27 Many thanks to Prof. Huang for the guidance and help in the paper supervision!!! Also, appreciate all the contributions from coauthors! Thanks. Autonomic Behaviors in Lipase-active Oil Droplets Lei Wang, Youping Lin (Equal contribution), Yuting Zhou, Hui Xie, Jianmin Song, Mei Li, Yudong Huang, Xin Huang*, and Stephen Mann*. Angew. Chem. 2018, DOI:10.1002/anie.201812111 https://onlinelibrary.wiley.com/doi/10.1002/anie.201812111 新闻标题 Congrats to Dr. Wang for the Angew. Chem. paper! 发布时间 Apr. 16, 2019 Lipase‐powered mesoporous silica nanomotors for triglyceride degradation https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201900697 新闻标题 Congratulations to Dr. Wang for the Best Oral Report Award on the ICMNM conference. 发布时间 2019-08-28 Dr. Wang delivered the talk entitled 'Novel bacterial/protocell models based on Lipase' on the ICMNM conference on 28th Aug. And he was one of the four Best Oral Report Awardees from 33 oral talks. Congrats!!! 新闻标题 Congrats to Dr. Lei Wang for the collaborated work published on Science Robotics! 发布时间 2019 Reconfigurable magnetic microrobot swarm: Multimode transformation, locomotion, and manipulation Science Robotics 4 (28), eaav8006 新闻标题 Congrats to our invited review paper on Biomimicy of cellular behaviors based on soft-architectures! 发布时间 2020-02-24 Congrats on our collobrated paper, with Prof. J. van Hest's group, Prof S. Sanchez's group and Prof. X. Huang, has been accepted for publication in Small. Many Thanks for all the support from three groups!!! 新闻标题 祝贺陈海旭同学的文章发表在德国应用化学Angew. Chem. Int. Ed.! 发布时间 2020-06-19 Congrats to Haixu and Coauthors for the paper accepted for publication on Angew. Chem. Int. Ed. https://www.onlinelibrary.wiley.com/doi/10.1002/anie.202004617 新闻标题 Congrats to Dr. Wang for the paper accepted for publication on Angew. Chem. Int. Ed.! 发布时间 2020-08-04 The paper discussing " Enzyme Conformation influnces the performance of lipase powered nanomotors' has been accepted for publication on Angew. Chem. Int. Ed.! Congrats to all the coauthors!!! Many thanks for Prof. Sanchez and Prof. Huang's support! And also appreciate all the help from all the coauthors, especially Paul, Marco, and Silvia, thanks! https://www.onlinelibrary.wiley.com/doi/10.1002/anie.202008339 新闻标题 Congratulations to Dr. Wang to join BMEMat as youth Editorial Board Member! 发布时间 2023-05-08 https://mp.weixin.qq.com/s/VP0iA5inv-zcc5yT7ir26A 代表论文 / Representative Publications 名称 迄今在 Angew. Chem. Int. Ed., Sci. Robotics., Adv. Funct. Mater., Small, Lab Chip, ACS Nano, Anal. Chem.等国际和国内高水平杂志上发表了100余篇高影响力论文，其中通讯作者（含第一作者）论文50余篇，所有文章中影响因子大于10的30余篇；论文被正面引用超过3000次。 5 Featured Research Papers in the past 5 years（五年内五篇代表作）: [1] Polyoxometalate-Nanozyme-Integrated Nanomotors (POMotors) for Self-Propulsion-Promoted Synergistic Photothermal-Catalytic Tumor Therapy M. Tang, J. Ni, Z. Yue, T. Sun*, C. Chen*, X. Ma*, L. Wang* Angew. Chem. Int. Ed. 2023, e202315031. [2] Enzyme Conformation Influnces the Performance of Lipase-powered Nanomotors. L. Wang, M. Marciello, M.E-Gay, P. E.D.S. Rodriguez, Y. Morato, J.I. Fernandez, X. Huang, S. Osuna, S. Sanchez*. Angew. Chem. Int. Ed. 2020, 59, 21080–21087. [3] Fusion-induced Structural and Functional Evolution in Binary Emulsion Communities. H.X. Chen, W.Li, Y.P. Lin, L. Wang*, X.M. Liu, and X. Huang*. Angew. Chem. Int. Ed. 2020, 59, 16953–16960. [4] Lipase-powered Mesoporous Silica Nanomotors for Triglyceride Degradation. L. Wang, A.C. Hortelao, X. Huang, and S. Sanchez* Angew. Chem. Int. Ed., 2019, 58, 7992-7996. [5] Autonomic Behaviors in Lipase-Active Oil Droplets, L. Wang, Y.P. Lin, Y.T. Zhou, H. Xie, J. Song, M. Li, Y.D. Huang, X. Huang*, and S. Mann*. Angew. Chem. Int. Ed., 2019, 58, 1067. Selected published papers（代表作）: [61] Polyoxometalate-Nanozyme-Integrated Nanomotors (POMotors) for Self-Propulsion-Promoted Synergistic Photothermal-Catalytic Tumor Therapy M. Tang, J. Ni, Z. Yue, T. Sun*, C. Chen*, X. Ma*, L. Wang* Angew. Chem. Int. Ed. 2023, e202315031. https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.202315031 [60] MOF-based micro/nanomotors (MOFtors): Recent progress and challenges. Y. H. Yang, L. Wang*, X. Huang* https://www.sciencedirect.com/science/article/pii/S0010854523003612?via=ihub Coordination Chemistry Reviews, 2023, 495, 215372. Highlighted by https://new.qq.com/rain/a/20230823A00UYA00 [59] Contaminats-fueled Laccase-powered Fe3O4@SiO2 Nanomotors for Synergistical Degradation of Multiple Pollutants. L. Wang*, Y. Huang, H. Xu, S. Chen, H. Chen, Y. Lin, X. Wang, X. Liu, S. Sánchez, X. Huang* Mater. Today Chem., 2022, 26, 101059. https://www.sciencedirect.com/science/article/pii/S2468519422002889 [58] Self-propelled micro/nanomotors for removal of insoluble water contaminants: microplastics and oil spills. L. Wang*, K. Villa*, Environ. Sci.: Nano, 2021, 8, 3440. (Invited Frontier) https://pubs.rsc.org/en/content/articlelanding/2021/en/d1en00663k [57] Enzyme Conformation Influnces the Performance of Lipase-powered Nanomotors. L. Wang, M. Marciello, M.E-Gay, P. E.D.S. Rodriguez, Y. Morato, J.I. Fernandez, X. Huang, S. Osuna, S. Sanchez*. Angew. Chem. Int. Ed. 2020, 59, 21080–21087. https://www.onlinelibrary.wiley.com/doi/abs/10.1002/anie.202008339 Hot Topic: Robotics https://www.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)2365-709X.hottopic-robotics [56] Fusion-induced Structural and Functional Evolution in Binary Emulsion Communities. H.X. Chen, W.Li, Y.P. Lin, L. Wang*, X.M. Liu, and X. Huang*. Angew. Chem. Int. Ed. 2020, 59, 16953–16960. https://www.onlinelibrary.wiley.com/doi/10.1002/ange.202004617 Hot Topic: Robotics https://www.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)2365-709X.hottopic-robotics [55] Photosynthetic hydrogen production by droplet-based microbial micro-reactors under aerobic conditions. Z. Xu, S. Wang, C. Zhao, S. Li , X.M. Liu, L. Wang, Mei Li,Xin Huang*, and S. Mann*. Nat. Commun., 2020, 11, 5985. https://www.nature.com/articles/s41467-020-19823-5 [54] Polymer-Chlorella Cells Conjugating with Aggregation-Induced Functionality Switch towards Hydrogen Evolution. S.L. Wang, Z. J. Xu, S. Lin, X.M. Liu,* L. Wang, and X. Huang.* Sci. China, Technological Sciences. 中国科学：技术科学, 2020. http://engine.scichina.com/doi/10.1007/s11431-020-1628-9 [53] Carbon dots-fed Shewanella oneidensis MR-1 for bioelectricity enhancement. C.H. Yang, H. Aslan, P. Zhang, S. Zhu, Y. Xiao, L. Chen, N. Khan, T. Boesen, Y. Wang, Y. Liu, L. Wang, Y. Sun, Y. Feng, F. Besesbacher, F. Zhao, M. Yu. Nat. Commun., 2020, 11, 1379. https://www.nature.com/articles/s41467-020-14866-0 [52] A Near-Infrared-Induced Contractile ProteinosomeMicroreactor with A Fast Control on Enzymatic Reaction. J.J. Su, H.X. Chen, Z. Xu, S.L. Wang., X.M. Liu*, L. Wang, and X. Huang* ACS Applied Materials & Interfaces, 2020 DOI:10.1021/acsami.0c11635 [51] Biomimicry of Cellular Motility and Communication Based on Synthetic Soft-Architectures L. Wang, S-D. Song, J. van Hest, L. K.E.A. Abdelmohsen*, X. Huang*, and S. Sanchez* Small, 2020, 16, 1907680. https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.201907680 Highlighted by MaterialsViews China: https://www.materialsviewschina.com/2020/04/44542/ 2019年 [50] Lipase-powered Mesoporous Silica Nanomotors for Triglyceride Degradation. L. Wang, A.C. Hortelao, X. Huang, and S. Sanchez* Angew. Chem. Int. Ed., 2019, 58, 7992-7996. https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201900697 [49] Autonomic Behaviors in Lipase-Active Oil Droplets, L. Wang, Y.P. Lin, Y.T. Zhou, H. Xie, J. Song, M. Li, Y.D. Huang, X. Huang*, and S. Mann*. Angew. Chem. Int. Ed., 2019, 58, 1067. https://www.onlinelibrary.wiley.com/doi/10.1002/anie.201812111 https://www.onlinelibrary.wiley.com/doi/10.1002/anie.201813837 [48] Enzyme-Modulated Anaerobic Encapsulation of Chlorella Cells Allows Switching from O2 to H2 Production, D. Su, J. Qi, X. Liu, L.Wang, H. Zhang, H. Xie, and X. Huang* Angew. Chem. Int. Ed., 2019, 58, 3992–3995. (VIP) https://www.onlinelibrary.wiley.com/doi/10.1002/ange.201900255 [47] Reconfigurable magnetic microrobot swarm: Multimode transformation, locomotion, and manipulation, H. Xie,* M. Sun, X. Fan, Z. Lin, W. Chen, L. Wang, L Dong*, Q. He* Sci. Robot. 2019, 4, eaav8006. (Science 子刊) 2018年 [46] Signal-On Electrochemiluminescence of Self-Ordered Molybdenum Oxynitride Nanotube Arrays for Label-Free Cytosensing L. Wang, D.Q. Liu, Y. Sun, J.J. Su, B.W. Jin, L. Geng, Y.-Y. Song*, X. Huang*, and M. Yang* Anal. Chem., 2018, 90 (18), 10858–10864. (Highlighted in the Journal homepage) [45] Design and Construction of Hybrid Microcapsules with Higher-Order Structure and Multiple Functions G.Y. Wu, L.Wang,* P.Zhou, P. Wen, C. Ma, X. Huang,* and Y.D. Huang* Adv. Sci., 2018, 5, 1700460. 2017年 [44] One-step self-assembly of hybrid Janus-like capsule for NIR-controlled release L. Wang, G.Y. Wu, X.M. Liu, and X. Huang* J. Controlled Release., 2017, 259, DOI:10.1016/j.jconrel.2017.03.169. [43] Single-step fabrication of multi-compartmentalized biphasic proteinosomes. L. Wang, P. Wen, X.M. Liu, Y.T. Zhou, M. Li, Y.D. Huang, L. Geng, S. Mann,* and X. Huang* Chem. Comm. 2017, 53, 8537-8540. http://dx.doi.org/10.1039/C7CC04180B. (Nature Indexed journal) [42] In Situ Generation of Core-Shell Protein-Based Microcapsules with Regulated Ion Absorbance Capacity P. Zhou, L. Wang,* G. Wu, Y. Zhou, M. Hegazy, and X. Huang* Chemistry Select, 2017, 2, 6249-6253. http://onlinelibrary.wiley.com/doi/10.1002/slct.201701339/full [41] Efficient Way to Generate Protein-based Nanoparticles by in-Situ Photoinitiated Polymerization-Induced Self-Assembly. C. Ma, X.M. Liu,* G.Y. Wu, P. Zhou, Y.T. Zhou, L. Wang, and X. Huang,* ACS Macro Lett., 2017, 6, 689-694. [40] In Situ Gelation-Induced Death of Cancer Cells Based on Proteinosomes Y. T. Zhou, J. M. Song, L.Wang*, X.T. Xue, X.M. Liu, H. Xie* and X. Huang* Biomacromolecules, 2017, 18 (8), 2446-2453. [39] Coordinated Membrane Fusion of Proteinosomes by Contact Induced Hydrogel Self-healing P. Wen, X.M. Liu, L. Wang, M. Li, Y.D. Huang, X. Huang* and S. Mann*. Small, 2017, 1700467. [38] Engineering DNA-based capsule used as a platform for carrying various molecules G. Wu, L. Wang, X. Huang*, and Y.D. Huang. J. Control. Release, 2017,259,36. 2016年 [37] Bio-inspired Engineering Proteinosomes with Cell Wall like Protective Shell by Self-assembly of Metal-chelated Complex D. Su, X.M. Liu,* L. Wang, C. Ma, H. Xie, H. Zhang, X. Meng, Y.D. Huang, and X. Huang* Chem. Comm., 2016, 52, 13803-13806. [36] Programmable modulation of membrane permeability of proteinosome upon multiple stimuli responses P. Zhou, X.M. Liu*, G.Y. Wu, P. Wen, L. Wang, Y.D. Huang, and X. Huang* ACS Macro Lett. 2016, 5, 961-966. [35] Formation of hybrid core-shell microgels induced by autonomous unidirectional migration of nanoparticles J.Y. Wang, K. Song, L.Wang, Y.J. Liu, B. Liu, J. Zhu, X. Xie, and Z.H. Nie* Mater. Horiz., 2016, 3, 78-82. [34] Light-triggered generation of multifunctional gas-filled capsules on-demand L. Wang, J.Y. Wang, K. Song, W. Li, Z.Q.Huang, J. Zhu, X. Han*, and Z.H. Nie* J. Mater. Chem. C, 2016, 4, 652-658. (Journal of Materials Chemistry C, Hot Paper) [33] CdS-modified Porous Foam Nickel for Label-free high Efficient Detection of Cancer Cells B. Dai, L.Wang *, J. Shao, X.Huang*, and G. Yu* RSC Adv., 2016, 6, 32874–32880. [32] Electrochemiluminescence Biosensor Based on CdS-modified Silica NPs for Cancer Cell Detection B. Dai, J. Shao, Y. Song, G. Yu, Y. Guan, L. Wang, D. Gao. Basic Clin. Pharmacol. Toxicol., 2016, 118,51. [31] Polyacrylate emulsion containing IBOMA for removable pressure sensitive adhesives L. Zhang, Y. Cao, L. Wang, L. Shao, Y. Bai* J. Appl. Polym. Sci., 2016, 133, 42886. 2015年 [30] Continuousmicrofluidic self-assembly of hybrid Janus-like vesicular motors: autonomous movement and controlled release L.Wang, Y.J. Liu (Equal contribution), J. He, M. J.Hourwitz, Y.L. Yang, J. Fourkas, X.Han* and Z.H. Nie* Small, 2015, 11, 3762–3767. (Featured by website of Harbin Institute of Technology) [29] Photosynthetic Proteinin Supported Lipid Bilayers - Towards a Biokleptic Approach for Energy Capture L. Wang, J. S. Roth, X.Han, and S. D.Evans* Small, 2015, 11, 3306-3318. [28] A NovelElectrochemiluminescence Immunosensor Based on CdS-Coated ZnO Nanorods array for HepG2 Cell Detection D. Liu, L.Wang (Equal contribution), S. Ma, Z. Jiang, B. Yang, X.Han*, and S.Q. Liu* Nanoscale, 2015, 7, 3627-3633. [27] Self-assembly via microfluidics L. Wang and S. Sanchez* Lab Chip, 2015, 15,4383-4386. [26] Morphology-controlled synthesis of Ag nanoparticles-decorated poly(o-phenylenediamine) using microfluidics and its application for hydrogen peroxide detection L. Wang, S. Ma, B. Yang, W. Cao, and X.Han* Chem. Eng. J. 2015, 268, 102-108. (JOURNAL FRONT COVER PAPER) [25] A novel porous adhesion material with ink absorbency for digital inkjet printing L. Zhang, Y. Cao, L.Wang*, L. Shao and Y. Bai* RSC Adv., 2015, 5, 36288–36294. [24] Preparation and properties of aligned graphene composites D. Li, Y. Liu, H.Ma, Y. Wang, L. Wang, and Z. Xie RSC Adv., 2015, 5, 31670-31676. [23] Preparation and properties of polyurethane modified epoxy cured in the different simulated gravity environments D. Li, Y. Liu, H.Kang, H. Tan, L. Wang, and C. Zhang J. Appl. Polym. Sci. 2015, 132, 42063. [22] A Highly Efficient ZrO2 Nanoparticle-Based Electrochemical Sensor for the Detection of OrganophosphorusPesticides H. Wang, Y. Su, H. Kim, D. Yong, L. Wang, and X.Han* Chin. J. Chem., 中国化学，2015, 33, 1135–1139. [21] Micromixingenhancement in a novel passive mixer with symmetrical cylindrical grooves L. Wang, S. Ma and X.Han* Asia-Pac. J. Chem. Eng. 2015, 10, 201-209. Before 2014 [20] Lipid nanotube formation using space regulated electric field above interdigitated electrodes H. Bi, Di. Fu, L.Wang, and X.Han* ACS Nano, 2014, 8 (4), 3961-3969. (Featured by the website of HarbinInstitute of Technology) [19] A novel quantum dot nanoclusters as versatile probe for electrochemiluminescence and electrochemical assays of DNA and cancer cells G.F. Jie, J. Zhang, G.Jie, and L. Wang Biosensors and Bioelectronics, 2014, 52, 69-75. [18] Interactions of the baicalin and baicalein with bilayer lipid membranes investigated by cyclic voltammetry and UV-Vis spectroscopy Y. Zhang, X.J. Wang, L.Wang, M. Yu and X.Han* Bioelectrochemistry, 2014, 95, 29-33. [17] Synthesis and properties of soap-free P(2-EHA-BA) emulsion for removable pressure sensitive adhesives L. Zhang, Y. Cao, L. Wang, L. Shao, and Y. Bai* RSC Adv., 2014, 4, 47708-47713. [16] The influences of different gravity environments on the curing process and cured products of carbon- nanotube-reinforced epoxy composites D. Li, Y. Liu, Y. Wang, H. Kang, L. Wang, and H. Tan J. Appl. Polym. Sci. 2014, 132, 41413. [15] Mixing enhancement of novel passive microfluidic mixers with triangle-baffles L. Wang, S. Ma, X. Wang, H. Bi, and X.Han* Asia-Pac. J. Chem. Eng. 2014, 9(6), 877-885. [14] Hydrodynamic-driven self-assembly of giant vesicles of metal nanoparticles for remote-controlled release J. He, Z. Wei, L.Wang, Z. Tomova, T. Babu, C. Wang, X.Han, J.Fourkas, and Z.H. Nie* Angew. Chem. Int. Ed., 2013, 52, 2463-2468. (Positive citation times>90 from GoogleScholar) [13] Electroformation of giant Unilamellar Vesicles Using Interdigitated ITO Electrodes H. Bi, B. Yang, L.Wang, W. Cao and X.Han* J. Mater. Chem. A, 2013, 1, 7125-7130. [12] Vesicularself-assembly of colloidal amphiphiles in microfluidics J. He, L. Wang (Equal contribution), Z. Wei, Y. Yang, C. Wang, X. Han, and Z.H. Nie* ACS Appl. Mater. Interfaces, 2013, 5, 9746-9751. [11] Forming Lipid BilayerMembrane Arrays on Micropatterned Polyelectrolyte Film Surfaces Y. Zhang, L.Wang, X. Wang, G. Qi, and X.Han Chem. Eur. J., 2013, 19, 9059- 9063. [10]ElectrochemiluminescentTiO2/CdS nanocomposites for efficient immunosensing of HepG2 cells L. Wang, S. Ma, X.J. Wang, D. Liu, S. Liu, and X.Han J. Mater. Chem. B, 2013, 1, 5021-5027. [9] Lipid Bilayer MembraneArrays: Fabrication and Applications X.Han, G. Qi, X. Xu, and L. Wang Adv. Biochem. Eng. Biot., 2013, 131, 121-152. [8] Migration of ChargedSpecies in Lipid Bilayer Membranes under an Electric Field X. Wang, L.Wang, X.Han and C. Guo* Nano, 2013, 8 (1), 1230006. [7] Fabrication of ChemicalGradient Using Space Limited Plasma Oxidation and its Application on DropletMotion X.Han*, L. Wang, and X.Wang Adv. Funct. Mater., 2012, 22, 4533-4538. (Featured by websites of MaterialsViewChina and Harbin Institute of Technology) [6] Mixing enhancement of novel passive mixers with cylindrical grooves L. Wang, Da. Liu, X. Wang, and X.Han* Chem. Eng. Sci., 2012, 81, 157-163. (Positive citation times>40 from GoogleScholar) [5] Formation of Lipid Bilayer Microarrays on Photo-Oxidized Polystyrene Surfaces X.Han, G. Qi, X. Xu, and L. Wang Chem. Eur. J., 2011, 17, 14741-14744. 2009-2011 Publications from QUST: [4] Versatile Electrochemiluminescence Assays for Cancer Cells Based on Dendrimer/CdSe-ZnS-Quantum Dot Nanoclusters G.F. Jie, L.Wang, J. Yuan, and S.S. Zhang* Anal. Chem., 2011, 83, 3873-3880. (Positive citation times>170 from GoogleScholar) [3] Magnetic Electrochemiluminescent Fe3O4/CdSe@CdS Nanoparticle/Polyelectrolyte Nanocomposite for Highly Efficient Immunosensing of a CancerBiomarker G.F. Jie, L. Wang, and S.S. Zhang* Chem. Eur. J., 2011, 17, 641-648. (Positive citation times>70 from GoogleScholar) [2]Electrochemiluminescence Imunosensor Based on Nanocomposite film of CdS QuantumDots-carbon Nanotubes Combined with Gold Nanoparticles-chitosan G.F. Jie, P. Liu, L.Wang, and S.S. Zhang* Electrochem. Commun., 2010, 12, 22-26. (Positive citation times>70 from GoogleScholar) [1] Label-free Electrochemiluminescence Imunosensor Based on Nanocomposite film of CdS Quantum Dots/carbon Nanotubes G.F. Jie, P. Liu, L.Wang, and S.S. Zhang* Chin. J. Anal. Chem., 中国分析化学, 2009, 10 (37), F106. 出版物 出版物名称 Nanomaterials for Tumor Targeting Theranostics: A Proactive Clinical Perspective 作者 Lei Wang, et al. 出版时间 2016/2/22 出版社 World Scientific 简单介绍 Chapter 10 Microbubbles for Tumor Targeting Theranostics 出版物名称 New protein-based smart materials 作者 Lei Wang and Xin Huang 出版时间 31 July 2020 出版社 Woodhead Publishing Series in Biomaterials 简单介绍 授权发明专利/Patent 专利名称 一种漆酶在纳米马达驱动中的应用 专利号 202110413196.7 发明人 王磊，黄勇维，黄鑫 申请时间 2021.06.16 专利类别 发明 简单介绍 https://kns.cnki.net/kcms2/article/abstract?v=kxaUMs6x7-4I2jr5WTdXti3zQ9F92xu0jPYZ-6FemR80TpIUx9Y4vvkl9jih6ebZkJQREhARtr9GWBbExRHm6dy9WxhfvgX8&uniplatform=NZKPT 专利名称 一种一步控温法制备含有洋葱状多层磷脂膜结构人工细胞的方法 专利号 ZL 20221 0039479.4 发明人 王磊，李宏凯，孙照玲，黄鑫 申请时间 2022.01.13 专利类别 发明 简单介绍 https://kns.cnki.net/kcms/detail/detail.aspx?dbcode=SCPD&dbname=SCPD202203&filename=CN114377627A&uniplatform=NZKPT&v=Fd1nkLCTRGrkhWIryAZlw9meb7J3s0lXOjpal8pyHNVAwblUmAju_DluhdqUYYud 专利名称 一种具有Janus结构人工细胞模型的尿素传感器的制备方法 专利号 ZL 201911383849.0 发明人 王磊，陈海旭，刘小曼，黄鑫 申请时间 2019.12.28 专利类别 发明 简单介绍 https://kns.cnki.net/kcms/detail/detail.aspx?dbcode=SCPD&dbname=SCPD202204&filename=CN111020004B&uniplatform=NZKPT&v=6GbHIobUY6LhEJI5d8bFCqG3lUJjVRsqiLWNy7dpfkqM099W3D6JA81geEgtxUFU 专利名称 一种膜通量可调控的无支撑Janus单分子层蛋白膜材料的制备方法 专利号 ZL 2019 1 0581078.X 发明人 王磊，孙照玲，林幼萍，刘小曼，黄鑫 申请时间 2019.06.29 专利类别 发明 简单介绍 https://kns.cnki.net/kcms/detail/detail.aspx?dbcode=SCPD&dbname=SCPD202202&filename=CN110194845B&uniplatform=NZKPT&v=1uTkHL6p-6BCRDXsptSWOpl4_xSIbcAD5gtS4loMJsAtj5NC8o5WSiA4xIJLvh8V 专利名称 一种基于天然纯蛋白质制备微胶囊提高界面催化反应效率的方法 专利号 ZL2017 1 0214104.6 发明人 王磊，刘小曼，周玉婷，黄鑫 申请时间 2017.04.01 专利类别 发明 简单介绍 https://kns.cnki.net/kcms/detail/detail.aspx?dbcode=SCPD&dbname=SCPD201902&filename=CN106987579B&uniplatform=NZKPT&v=OskiHYkxFuS-7uVh1P2fZsyUtV7JcayHfUPii2uFyNDMCdHQu2EoRIPHIVmjg20n 专利名称 一种利用pH调控癌细胞凝胶化微胶囊的制备方法及利用该微胶囊杀死癌细胞的检测方法 专利号 ZL2016 1 1072724.2 发明人 王磊，周玉婷，谢晖，宋建民，黄鑫 申请时间 2016.11.29 专利类别 发明 简单介绍 https://kns.cnki.net/kcms/detail/detail.aspx?dbcode=SCPD&dbname=SCPD202001&filename=CN106551917B&uniplatform=NZKPT&v=SbcY35bvOZ-AOL3o0CbrRSeOp28VdXkSE0bueQlYQAzXy7Ppm92jw6Q9zzvxI0Ou