周俊平科研成果

个人简介 周俊平，男，博士、特聘副研究员、硕士生导师，江西抚州人。2019年1月获得江南大学发酵工程专业博士学位，2019年2月到2020年8月期间在美国奥本大学从事生物燃料制备的博士后研究。主要从事酶的理性设计及定向改造、生物级联反应及代谢工程等方面课题，以第一或共一作者在ACS catalysis， Advanced Materials, Current Opinion in Chemical Biology, Biotechnology Journal等SCI期刊发表论文，影响因子总和大于50，并获多项专利授权。参与国家863项目等国家级与省部级项目，担任Frontier in Bioengineering and Biotechnology及3 Biotech的Review editor，获第三届“互联网+”大学生创新创业大赛全国铜奖及江苏省一等奖。 教学与课程 参加“合成生物学”等研究生课程教学。 育人成果 科研项目 大肠杆菌合成苏氨酸衍生的非天然氨基酸底盘细胞设计与构建，国家自然科学基金青年基金项目，2022.01-2024.12，主持 科研成果 代表性论文论著1.       J.P. Zhou, R.Z. Zhang,* T.W. Yang, Q.L. Liu, J.X. Zheng, F. Wang, F. Liu, M.J. Xu, X. Zhang, Z.M. Rao.* 2018. Relieving allosteric inhibition by designing active inclusion bodies and coating of the inclusion bodies with Fe3O4 nanomaterials for sustainable 2-oxobutyric acid production. ACS catalysis, 8(9), 8889-8901. 2.       J.P. Zhou, Z. Chen, Y. Wang. * 2020. Bioaldehydes and beyond: expanding the realm of bioderived chemicals using biogenic aldehydes as platforms. Current Opinion in Chemical Biology, 59, 37-46.3.       J.P. Zhou, Y.L. Wang, J.J. Chen, M.J Xu,* T.W. Yang, J.X. Zheng, X. Zhang, Z.M. Rao.* 2019. Rational engineering of Bacillus cereus leucine dehydrogenase towards α-keto acid reduction for improving unnatural amino acid production. Biotechnology Journal, 14(3), e1800253.4.       R.Z. Zhang,* J.W. Jiang, J.P. Zhou, Y. Xu,* R. Xiao, X.H. Xia, Z.M. Rao.* 2018. Biofunctionalized kiwifruit-assembly of oxidoreductases in mesoporous ZnO/carbon nanoparticles for efficient asymmetric catalysis. Advanced Materials, 1705443. 5.       L.Z. Tian†, J.P. Zhou†, Q.L. Lv, F. Liu, T.W. Yang, X. Zhang, M.J. Xu*, Z.M. Rao*. 2021. Rational engineering of the Plasmodium falciparum L-lactate dehydrogenase loop involved in catalytic proton transfer to improve chiral 2-hydroxybutyric acid production. International Journal of Biological Macromolecules, https://doi.org/10.1016/j.ijbiomac.2021.02.144.6.       F. Liu†, J.P. Zhou†, M.J. Xu, T.W. Yang, M.L. Shao, X. Zhang*, Z.M. Rao*. 2020. One-pot biocatalytic preparation of enantiopure unusual α-amino acids from α-hydroxy acids via a hydrogen-borrowing dual-enzyme cascade.Catalysts, 10, 1470.7.       J. Feng†, J. Zhang†, Y.C. Ma†, Y.M. Feng, S.J. Wang, N. Guo, H.J. Wang, P.X. Wang, P. Jiménez-Bonilla, Y.Y. Gu, J.P. Zhou, Z.T. Zhang, M.F. Cao, D. Jiang, S.N. Wang, X.W. Liu, Z.Y. Shao, I. Borovok, H.B. Huang* & Y. Wang*. 2021. Renewable fatty acid ester production in Clostridium.Nature communication,12, 4368. 发明专利1.     一种亮氨酸脱氢酶突变体的构建及其应用，发明专利，专利号：CN108559735B2.     一种高效合成α-氨基丁酸的单细胞工厂及其构建与应用，发明专利，专利号：CN106399216B；3.     一种苏氨酸脱氨酶活性包涵体的制备及其应用，发明专利，专利号：CN105296455B4.     Single-cell factory for efficiently synthesizing α-aminobutyric acid and construction and application thereof，PCT专利，专利号：US10612054B2 社会服务 内容来自集群智慧云企服 请访问正版网址 www.jiqunzhihui.net