杨文

基本信息 男，1984年出生，江西南昌人。2008年本科毕业于陕西师范大学，2014年于北京理工大学获博士学位（导师：杜大明教授）。2014年6月至2016年8月于香港科技大学从事博士后研究（合作导师：孙建伟教授）。2016年9月被聘为湖南大学化学化工学院副教授,研究方向为有机合成方法学，主要从事不对称催化反应研究，已在Angew. Chem., Int. Ed.、Chem. Sci.、Org. Lett.及Chem. Commun.等重要国际期刊上以第一或通讯作者发表SCI论文30余篇，引用1000多次，H指数达17；获中国发明专利1项。

教育背景

教育背景 2008.09-2014.03        北京理工大学        工学博士2004.09-2008.07          陕西师范大学          理学学士

工作履历

工作履历 2016.09-现在                湖南大学 化学化工学院           副教授、博士生导师2014.06-2016.08        香港科技大学 化学系    博士后

研究领域

研究领域 1）设计合成新型有机小分子催化剂和手性配体，发展高效不对称催化合成方法2）开发催化合成方法应用于有机染料的制备

学术成果

学术成果   26. Zhou, H.; Yang, W.*; Yuan, L.; Zhang, X.-B.; Ren, T.-B.*Rational engineering of novel rhodamines with stable far red to NIR emission and high brightness for in vivo imaging. Sensors & Actuators: B. Chemical 2024, 401, 135074. 25. OuYang, M.; Yuan, M.; Li, J.*; Yang, W.* Brønsted Acid-Catalyzed Tandem Double Friedel–Crafts Alkylation to Construct a Dihydrophenalene Skeleton Bearing an All-Carbon Quaternary Center. J. Org. Chem.2024,89, 576-588.  24. Fan, X.*; Wang, H.; Yang, W.*; Ren, T.-B.*; Yuan, L. Ratiometric photoacoustic imaging of endogenous HNO in vivo forassessing prodrug release and liver injury. Chem. Commun. 2023, 59, 8969-8972. 23. Li, C.; Qin, Q.; Guan, A.; Yang, W.*; Zhao, W.*  Transition-Metal Free C−C Bond Cross-Coupling of Aryl Ethers with Diarylmethanes.  J. Org. Chem. 2023, 88, 7525-7534.  22. Li, J.; Zhang, X.; Yao, Y.; Gao, Y.; Yang, W.*; Zhao, W.* Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling of Oxygen- Substituted Allylboronates with Aryl/Vinyl (Pseudo)Halides.   J. Org. Chem. 2022, 87, 6951-6959. 21. Zhao, P.; Huang, J. X.; Li, J.; Zhang, K. Z.; Yang, W.*; Zhao, W.* Ligand-controlled cobalt-catalyzed remote hydroboration and alkene isomerization of allylic siloxanes. Chem. Commun. 2022, 58, 302-305. 20. Li, J.; Zhao, P.; Li, R. L.; Yang, W.*; Zhao, W. * Rhodium-Catalyzed Dehydroborylation of Silyl Enol Ethers: Access to Highly Functionalized Enolates. Org. Lett. 2021, 23, 9580-9585.  19. Fan, X.; Ren, T.; Yang, W.*; Zhang, X.; Yuan, L.*Activatable photoacoustic/fluorescent dual-modal probe for monitoring of drug-induced liver hypoxia in vivo.  Chem. Commun. 2021, 57, 8644-8647. 18. Zhang, W.; Yang, W.*; Zhao, W.* Lewis Acid-Mediated Electrophilic Cyanation of 2,2'-Biphenols. J. Org. Chem. 2020, 85, 8702-8713. 17. Wang, W.; Xiong, W.; Wang, J.*; Wang, Q.-A.*; Yang, W.* Brønsted Acid-Catalyzed Asymmetric Friedel–Crafts Alkylation of Indoles with Benzothiazole-Bearing Trifluoromethyl Ketone Hydrates. J. Org. Chem. 2020, 85, 4398-4407. 16.  Dong, W.; Yang, H.;Yang, W.*; Zhao, W.* Rhodium-Catalyzed Remote Isomerization of Alkenyl Alcohols to Ketones. Org. Lett. 2020, 22, 1265-1269. 15.  Sun, G.; Zou, X.; Wang, J.*; Yang, W.* Sulfur-directed palladium-catalyzed C(sp3)-H α-arylation of 3-pyrrolines: easy access to diverse polysubstituted pyrrolidines. Org. Chem. Front. 2020, 7, 666-671. 14. Zou, X.;  Sun, G.; Huang, H.; Wang, J.*; Yang, W.*; Sun, J.* Catalytic Enantioselective Synthesis of 1,4-Benzodioxepines. Org. Lett. 2020, 22, 249-252. 13.  Huang, H.; Yang, W. (co-first author); Chen, Z. (co-first author); Lai, Z.; Sun, J.* A mild catalytic synthesis of 2-oxazolines via oxetane ring-opening: rapid access to a diverse family of natural products. Chem. Sci. 2019, 10, 9586-9590. 12.  Xiong, W.; Li, S.; Fu, B.; Wang, J.*; Wang, Q.-A.*; Yang, W.* Visible-Light Induction/Brønsted Acid Catalysis in Relay for the Enantioselective Synthesis of Tetrahydroquinolines. Org. Lett. 2019, 21, 4173-4176. 11.  Yang, W.; Ma, D. (co-first author); Zhou, Y.; Dong, X.; Lin, Z.;*  Sun, J.* NHC-Catalyzed Electrophilic Trifluoromethylation: Efficient Synthesis of γ-Trifluoromethyl         Unsaturated Esters. Angew. Chem., Int. Ed. 2018, 57, 12097-12101. 10.  Yang, W.; Hu, W.; Dong, X.; Li, X.; Sun, J.* N-Heterocyclic Carbene Catalyzed γ-Dihalomethylenation of Enals by Single-Electron Transfer.  Angew. Chem., Int. Ed. 2016, 55, 15783-15786. 9.    Yang, W.; Wang, Z.; Sun, J.* Enantioselective Oxetane Ring Opening with Chloride: Unusual Use of Wet Molecular Sieves for the Controlled Release of HCl. Angew. Chem., Int. Ed. 2016, 55, 6954-6958. 8.    Yang, W.; Sun, J.*Organocatalytic Enantioselective Synthesis of 1,4-Dioxanes and Other Oxa- Heterocycles by Oxetane Desymmetrization. Angew. Chem., Int. Ed. 2016, 55, 1868-1871. 7.    Dong, X.; Yang, W.; Hu, W.; Sun, J.* N-Heterocyclic Carbene Catalyzed Enantioselective α-Fluorination of Aliphatic Aldehydes and α-Chloro Aldehydes: Synthesis of α-Fluoro Esters, Amides, and Thioesters. Angew. Chem., Int. Ed. 2015, 54, 660-663. 6.    Yang, W.; He, H.-X.; Gao, Y.; Du, D.-M.* Organocatalytic Cascade Aza-Michael/Michael Addition Reactions for Enantioselective Synthesis of Functionalized Tetrahydroquinolines and Tetrahydrochromano- quinolines. Adv. Synth. Catal. 2013, 355, 3670-3678. 5.    Yang, W.; Yang, Y.; Du, D.-M.* Squaramide-Tertiary Amine Catalyzed Asymmetric Cascade Sulfa- Michael/Michael Addition via Dynamic Kinetic Resolution: Access to Highly Functionalized Chromans with Three Contiguous Stereocenters. Org. Lett. 2013, 15, 1190-1193. 4.    Yang, W.; Du, D.-M.* Squaramide-Catalyzed Cascade Aza-Michael/Michael Addition: Enantioselective Construction of Functionalized Spirooxindole Tetrahydroquinolines. Chem. Commun. 2013, 49, 8842-8844. 3.    Yang, W.; Du, D.-M.* Chiral Squaramide-Catalyzed Highly Diastereo- and Enantioselective Direct Michael Addition of Nitroalkanes to Nitroalkenes. Chem. Commun. 2011, 47, 12706-12708. 2.    Yang, W.; Du, D.-M.* Chiral Squaramide-Catalyzed Highly Enantioselective Michael Addition of 2-Hydroxy-1,4-naphthoquinones to Nitroalkenes. Adv. Synth. Catal. 2011, 353, 1241-1246. 1.  Yang, W.; Du, D.-M.* Highly Enantioselective Michael Addition of Nitroalkanes to Chalcones Using Chiral Squaramides as Hydrogen Bonding Organocatalysts. Org. Lett. 2010, 12, 5450-5453.