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导航 个人简介 学习经历 工作经历 研究方向 主要论文 主要著作 承担课题,个人信息 姓名: 崔淼 部门: 生命科学技术学院 直属机构: 水生生物研究中心 性别: 男 职务: 副研究员 职称: 副研究员 学位: 博士 毕业院校: 中山大学 联系电话: 13430254870 电子邮箱: cuisanshui@163.com 办公地址: 生科院水生所307房 通讯地址: 广州市黄埔大道西601号 邮编: 510632 联系方式 学习经历 2003.9 -- 2006.12 中山大学,博士学位,导师林浩然院士 2000.9 -- 2003.7 华南师范大学,硕士学位, 导师陈湘粦、赵俊教授 1996.9 -- 2000.7 华南师范大学,学士学位 研究方向 水生经济动物良种繁育、水产动物生态养殖、水产病害免疫防控、水产品质量安全和休闲渔业等。 主要论文 1、 Miao Cui *, Zibin Wang, Yongchun Yang, Ru Liu, Min Wu, Yujie Li, Qizhong Zhang and Delin Xu *. Comparative Transcriptomic Analysis Reveals the Regulated Expression Profiles in Oreochromis niloticus in Response to Coinfection of Streptococcus agalactiae and Streptococcus iniae. Frontiers in Genetics, 2022, doi: 10.3389/fgene.2022.782957.2、 Qiting Liang, Ganxing Liu , Zheng Guo, Yuting Wang, Zhongheng Xu, Yuxian Ren, Qizhong Zhang**, Miao Cui***, Xinqing Zhao****, Delin Xu*. Application of potential probiotic strain Streptomyces sp. SH5 on anti-Aeromonas infection in zebrafish larvae. Fish and Shellfish Immunology, 127 (2022): 375–385.3、 Yunwen Bi, Ganxing Liu, Qiushi Yu, Qiting Liang, Zhongheng Xu, Miao Cui *, Qizhong Zhang*, Delin Xu*. Anti-Vibrio dibutyl phthalate from marine-derived Streptomyces sp. S073. Research in Veterinary Science, 2021,140: 198-202.4、 Tinglong Hou†, Delin Xu†, Miao Cui, Huiru Liu, Yaowu Fu, Lingli Zhang, Lei Tang, Yanmeng Liu, Qizhong Zhang*.The transcriptional factor GATA-4 negatively regulates Hsp70 transcription in Crassostrea hongkongensis. Molecular Biology Reports, 2020 47:7107–7114. DOI: 10.1007/s11033-020-05778-9.5、 Jun Zhang, Qiting Liang, Zhongheng Xu, Miao Cui, Qizhong Zhang, Sonia Abreu, Michelle David, Clara Lejeune, Pierre Chaminade, Marie-Joelle Virolle, Delin Xu*. The inhibition of antibiotic production in Streptomyces coelicolor over-expressing the TetR regulator SCO3201 is correlated with changes in the lipidome of the strain. Frontiers in Microbiology, 2020, doi: 10.3389/fmicb.2020.01399.6、 Yao-Wu Fu, Zhan-Juan Yao, Meng-Han He, Zuo-Pei Wang, Wei-Feng Chen, Miao Cui , Qi-Zhong Zhang. Expression analysis and tissue localization of IgZ in the grouper Epinephelus coioides after Vibrio alginolyticus infection and vaccination. Journal of Fish Diseases, 2021, 44(10):1647-1655.7、 Miao Cui, Huijie Zhang, Jingjing Li, Ru Liu, Min Wu, Delin Xu*, QizhongZhang*. Differential PCR detection of Streptococcus agalactiae and Streptococcus iniae in tilapia (Oreochromis niloticus) by a single primer pair. Journal of Fish Diseases, 2019, 42(8):1211-1216.8、 Mingxia Yang, Jun Zhang, Qiting Liang, Guanxin Pan, Jiachang Zhao, Miao Cui, Xinqing Zhao, Qizhong Zhang, Delin Xu* . Antagonistic activity of marine Streptomyces sp. S073 on pathogenic Vibrio parahaemolyticus. Fisheries Science, 2019, 85: 533–543. 9、 Delin Xu#, Di Wang#, Miao Cui, Qizhong Zhang*. The purine-rich element-binding protein ChPur-α negatively regulates Hsc70 transcription in Crassostrea hongkongensis. Cell Stress and Chaperones, 2018, 23: 91-100.10、 Huiru Liu#, Delin Xu#, Miao Cui, Tinglong Hou, Qizhong Zhang*. The transcriptional factor YB-1 positively regulates Hsc70 transcription in Crassostrea hongkongensis. Biochemical and Biophysical Research Communications, 2018, 495: 2404-2409.11、 Lingli Zhang#, Delin Xu#, Miao Cui, Lei Tang, Tinglong Hou, Qizhong Zhang*. The guanine nucleotide-binding protein α subunit protein ChGnaq positively regulates Hsc70 transcription in Crassostrea hongkongensis. Biochemical and Biophysical Research Communications, 2018, 499: 215-220.12、 Delin Xu#, Qin Yang#, Miao Cui*, Qizhong Zhang*. The novel transcriptional factor HP1BP3 negatively regulates Hsp70 transcription in Crassostrea hongkongensis. Scientific Reports, 2017, DOI:10.1038/s41598-017-01573-y.13、 Delin Xu, Miao Cui, Qizhong Zhang*. Transcriptional Activity of Full-Length and Truncated Metallothionein Promoters of Crassostrea hongkongensis in Response to Metal Stress. Journal of Shellfish Research, 2016, 35 (1): 83–89.14、 Zongyu Miao#, Delin Xu#, Miao Cui, Qizhong Zhang*. High mobility group protein DSP1 negatively regulates HSP70 transcription in Crassostrea hongkongensis. Biochemical and Biophysical Research Communications, 2016, 474 (4): 634-639.15、 Delin Xu#, Bo Yu#, Yan Zhang, Miao Cui, Qizhong Zhang*. Metallothionein Protein Expression of Crassostrea hongkongensis in Response to Cadmium Stress. Journal of Shellfish Research, 2015, 34(2):311-318.16、 Yaozhuan. Yao, QizhongZhang*, Miao Cui. Immunoglobulin D gene cDNA cloning and expression analysis of the orange-spotted grouper (Epinephelus coioides) following Vibrio alginolyticus challenge. Fish and Shellfish Immunology, 2013, 34: 1749.17、 Miao Cui, Qizhong Zhang*, Zhanjuan Yao, Zhanhui Zhang. Molecular cloning and expression analysis of HSP70 in orange-spotted grouper, Epinephelus coioides, following heat shock and Vibrio alginolyticus challenge. Journal of Fish Biology, 2011, 79(2): 486-501.18、 Miao Cui, Qizhong Zhang*, Zhanjuan Yao, Zhanhui Zhang, Haifa Zhang, Yunxin Wang. Immunoglobulin M gene expression analysis of orange-spotted grouper, Epinephelus coioides, following heat shock and Vibrio alginolyticus challenge. Fish and Shellfish Immunology, 2010, 29: 1060-1065.19、 Miao Cui#, Wensheng Li#, Kai Yang, Yi Pang, Haoran Lin*. Biological Activity of Recombinant Orange-spotted Grouper (Epinephelus coioides) gonadoropin Hormone IIβ, Produced in Insect Cells by the Baculovirus Expression System. Cybium, 2008, 32(2): 50-51.20、 Miao Cui#, Wensheng Li#, Wen Liu, Kai Yang, Yi Pang, Haoran Lin*. Production of recombinant orange-spotted grouper (Epinephelus coioides) luteinizing hormone in insect cells by the baculovirus expression system and its biological effect. Biology of Reproduction, 2007, 76(1): 74-84.21、 Cui Miao#, Li wensheng#, Liu wen, Yang Kai, Pang Yi, Lin Haoran*. Biological Activity of Recombinant Orange-spotted Grouper (Epinephelus coioides) Gonadotropin Hormone IIβ Produced in Insect Cells by the Baculovirus Expression System. The Proceedings of the 8th ISRPF. 200722、 Miao Cui#, Wensheng Li# , Kai Yang , Yi Pang , Haoran Lin*. Recombinant orange-spotted grouper (Epinephelus coioides) GTH II in insect cells by baculovirus expression system: effect on estradiol-17β release from gonad. 13th International Congress on Genes, 2005: 42-43.23、 崔淼, 李钰杰, 杨永春, 张佳颖,许鲜姬,林李泉,林国荣,张其中,许德麟*. 黄鳍棘鲷IGF-2基因克隆及IGF-1/2在胚胎发育过程中的表达特性分析. 海洋学报, 2022, 44 (10): 152-162. 24、 崔淼*,王梓斌,李钰杰,林李泉,林国荣. 黄鳍鯛苗种淡化技术研究. 水产养殖,2021,6:67-69.25、 崔淼*,王梓斌,李钰杰,林李泉,林国荣. 黄鳍鲷池塘高效养殖技术. 农村科学实验,2021:106-107.26、 崔淼*,刘茹,张辉杰,叶长鹏,许德麟,张其中*. 100 种中草药对无乳链球菌和海豚链球菌体外抑杀研究. 生态科学, 2019, 38(4): 71-76.27、 崔淼,吴敏,刘茹,黎晶晶,张辉杰,许德麟*,张其中. 无乳链球菌和海豚链球菌早期预警分子检测. 水产科学, 2021, 40(4): 589-595.28、 崔淼,王梓斌,张佳颖,梁志辉,黄凤清. 澳洲淡水龙虾高效池塘生态养殖技术. 渔业致富指南, 2021, 12:47-50. 29、 杨文燕,张佳颖,梁志辉,黄凤清,崔淼*. 红螯螯虾与水稻共作种养技术. 2021, 24:50-51. 30、 崔淼,赵俊*,陈湘粦.卷口鱼的年龄和生长. 华南师范大学学报(自然科学版),2001(4):9-15.31、 崔淼,赵俊*,刘良国,陈湘粦.丰产鲫及其双亲肌蛋白和同工酶的比较研究.水产科学,2003,22(3):10-13. 32、 崔淼,赵俊.鱼类的辅助呼吸器官,生物学通报,2003,38(10):39-40.33、 赵俊*,崔淼,陈湘粦.异精效应在雌核发育彭泽鲫胚胎发育同工酶表型中的发现.水生生物学报,2004,28(1):33-39.34、 赵俊*,崔淼,庆宁,陈湘粦. 异精激发彭泽鲫雌核发育产生子代及其双亲血清蛋白和同工酶的比较研究.华南师范大学学报(自然科学版),2004(1):96-101.35、 刘良国,赵俊*,崔淼,陈湘粦. 尖鳍鲤的染色体组型研究. 华南师范大学学报(自然科学版),2004(1):108-111.36、 刘良国,赵俊*,崔淼. 鱼类的性别决定与人工控制. 水产科学,2003,22(2):42-45.37、 LIU Liang-guo, ZHAO Jun*, CUI Miao, DONG Cheng-wen, CHEN Xiang-lin. RAPD analysis of two clones in gynogenetic pengze crucian carp, Carassius auratus of pengze. International Workshop on Fish Genetics and Development. 2004, p95.38、 刘良国,赵俊*,陈湘粦,董成稳,崔淼. 彭泽鲫两个雌核发育克隆的染色体组型分析.遗传学报,2004,31(8):780-786. 承担课题 1. 广东省现代农业产业技术体系创新团队项目,岗位科学家 ((2019-2023KJ146).2. 广东省基础与应用基础研究基金,CXCL10基因在无乳和海豚链球菌感染罗非鱼过程中的转录调控机制研究(2022A1515012499)3. 广东省科技计划项目,特色水产品良种繁育、生态养殖和病害综合防治技术指导(KTP20210324)粤科资字〔2022〕9号324210794. 广东省基础与应用基础研究基金,罗非鱼主养及鱼虾混养模式的微生态差异化机制研究(2019A1515012112)5. 广东省科技专项资金项目,广东特色水产品生态养殖技术集成与示范指导 (粤财科教〔2019〕170号),6. 广州市产学研协同创新重大专项,罗非鱼链球菌早期分子诊断试剂盒的研发及应用(201604020029)7. 广州市科技计划项目,咸淡水鱼类多营养级生态养殖模式的研究与应用(GZKTP202032)8. 广东省渔港建设和渔业产业发展专项,罗非鱼链球菌分子流行病学调查及防治安全产品研究(A201601B05)9. 暨南大学引进优秀人才科研启动基金,斜带石斑鱼免疫球蛋白基因对溶藻弧菌感染的免疫反应研究(50624065)10. 广东省自然科学基金,近江牡蛎热休克蛋白70基因克隆及其对环境污染物的反应(07300378),11. 中国博士后科学基金一等资助金,近江牡蛎HSP70 cDNA克隆及其对几种环境污染物及组合的响应(20070420144)12. 广东省农业农村厅招标课题,2022年广东省农业外来入侵物种普查(0835-220Z52107801-4-3)13. 阳西县恒生水产合作社,黄鳍鲷良种选育及生态养殖技术(20210101)14. 农业部热带亚热带水产资源利用与养殖实验室开放课题,基于微生态学研究鱼虾混养对鱼体及池塘水质的影响机制(2019002)15.中山龙之泉农业科技发展有限公司,红螯螯虾良种选育及稻虾生态养殖研究(20210401) 发明专利 崔淼,张辉杰、许德麟,张其中。一对同时快速检测无乳链球菌和海豚链球菌的引物及其应用,国家发明专利,专利号: ZL201810386682.2 IPC分类号:C12Q1/689 ;C12Q1/14 ;C12N15/11 ;C12R1/46 ; 证书号:3321709。崔淼,黎晶晶,张辉杰、许德麟,张其中。双重,国家发明专利,专利号: ZL201910241560.9 IPC分类号:C12Q1/689 ; C12Q1/686 ;C12Q1/14 ;C12N15/11 ;C12R1/46 ;证书号:5157682。 讲授课程 本科课程:《普通动物学》、《生态学分子方法、技术及应用》、《水生动物生态养殖技术》、《水产动物营养与饲料》等研究生课程:《水产动物免疫学》、《生物多样性与保护生物学》