白卫滨

导航 个人简介 学习经历 工作经历 研究方向 主要论文 主要著作 承担课题,个人信息 姓名： 白卫滨 部门： 理工学院 直属机构： 理工学院 性别： 男 职务： 理工学院副院长，兼食品科学与工程系主任，食品安全与营养研究院常务副院长 职称： 教授 学位： 博士 毕业院校： 中国农业大学 联系电话： 02085226635 电子邮箱： baiweibin@163.com 办公地址： 暨南大学第二理工楼465 通讯地址： 广州天河区黄埔大道西601号 邮编： 510632 传真： 02085226635 荣誉奖励： 国家级青年人才,省级青年人才 联系方式 Email：baiweibin@163.com 个人简介 白卫滨，博士，教授，博士生导师。任暨南大学理工学院副院长，兼食品科学与工程系主任、食品安全与营养研究院常务副院长，广东省食品安全分子快速检测工程技术中心主任，广东省食品学会青年工作委员会主任，中国食品科学技术学会第三届青年工作委员会委员，食品领域TOP期 刊 Critical Reviews in Food Science and Nutrition 和Food and Chemical Toxicology杂志客座主编。入选教育部新世纪优秀人才支持计划，广东省高校优秀青年教师培养计划。任暨南大学食品安全与营养方向学科带头人，主要研究方向为富含花色苷果蔬的产品开发及功能研究、食物中有害物风险评估及营养干预、食品分子快速检测溯源技术等。近年来主持了国家自然科学基金 5 项，国家重点研发计划课题任务1 项，“十二五”国家科技支撑计划课题 1 项,广东省重点研发计划1项，广州市民生科技重大专项1项，到账经费累计1600多万元。以第一作者或者通讯作者发表学术论文 70余篇，其中已第一或者通讯作者发表在食品领域top 期刊《Critical Reviews in Food Science and Nutrition 》、《Journal of Agricultural and Food Chemistry》、《Food Chemistry》等SCI Top期刊论文50余篇。申请发明专利10项，授权 5项，并转让2项。起草地方标准2项（第一和第二起草人）。参编著作 4 部（其中副主编 1 部）。 学习经历 1998.9～2002.6，山东农业大学食品科学与工程专业，本科2004.9～2006.6，暨南大学微生物与生化药学专业，硕士2006.9～2009.12，中国农业大学食品科学专业，博士 工作经历 2002.9-2010.3，山东农业工程学院，讲师2010.3至今，暨南大学理工学院食品科学与工程系，教授/博导2012.11月至今，暨南大学理工学院副院长/食品安全与营养研究院常务副院长/食品科学与工程系主任/科技处副处长 研究方向 （1）食品天然功能花色苷等对慢性疾病营养干预：采用蓝莓、草莓等果蔬中花色苷，国际上率先开展了对生殖损伤的营养干预，建立了对生殖功能评价的体系和细胞及动物模型评价平台；同时对皮肤光老化、脂质代谢、血糖和肝损伤等营养干预也开展了系列研究；利用平台体系筛选药食同源功能活性因子，配伍并研发男性和女性备孕产品、护肤产品、减肥及护肝产品等。（2）研究花色苷标准样品制备、产品开发及色泽控制：（a）快速、高效的果蔬花色苷单体等生物活性物质的提取、分离、鉴定与纯化技术体系；（b）富含花色苷产品的果酒和果醋功能产品的开发；（c）富含花色苷产品加工和贮藏过程中色泽的变化及护色技术研究。（3）研究花色苷稳态化体系：针对花色苷抗氧化能力强，但稳定性差、吸收率低等缺点，采用壳聚糖、环糊精等构建稳态化的纳米/微米包埋体系，并研究精准靶向释放，开发花色苷功能配料。（4）研究食品分子溯源，核酸适配体快检技术、解毒营养干预：针对食品特别是高附加值食品掺假乱像，建立了食品种属鉴定和地理标识检测技术。开展了核酸适配体对重金属、毒素、微生物、激素等的筛选及快检技术和快检试剂盒产品的研究开发。利用核酸适配体技术开展污染物的体内解毒研究。 主要论文 代表性论文：[1] Cai DB, Li XS, Chen JL, Jiang XW, Ma XQ, Sun JX, Tian LM, Vidyarthi SK, Xu JW, Pan ZL, Bai WB*. A comprehensive review on innovative and advanced stabilization approaches of anthocyanin by modifying structure and controlling environmental factors. Food Chemistry, 2021, DOI10.1016/j.foodchem.2021.130611. (IF=7.514，1区Top)[2] Jiang XW, Li X, Feng WJ, Qin YG, Li Zhen, Nie H, Qin WB, Han L*, Bai WB*. Baking of methionine-choline deficient diet aggravates testis injury in mice. Food and Chemical Toxicology, 2021, DOI10.1016/j.fct.2021.112245. (IF=6.023, 1区Top)[3] Luo ZY, Duan HY, Yang YC, Zhang WT, Ramaswamy HS, Bai WB*, Wang C. High pressure assisted extraction for cadmium decontamination of long rice grain. Food Control, 2021, DOI10.1016/j.foodcont.2021.107987. (IF=5.548, 1区)[4] Chen JL, Xu BJ, Sun JX, Jiang XW, Bai WB*. Anthocyanin supplement as a dietary strategy in cancer prevention and management: A comprehensive review. Critical Reviews in Food Science and Nutrition, 2021, DOI10.1080/10408398.2021.1913092.(IF=11.176, 1区 Top)[5] Li XS, Li HW, Cai DB, Li P, Jin JT, Jiang XW, Li ZH, Tian LM, Chen GB, Sun JX, Bai WB*. Chronic oral exposure to cadmium causes liver inflammation by NLRP3 inflammasome activation in pubertal mice. Food and Chemical Toxicology, 2020, DOI10.1016/j.fct.2020.111944. (IF=6.023, 2区Top)[6] Li XS, Zhang L, Peng ZY, Zhao YQ, Wu, KY, Zhou N, Yan Y, Ramaswamy, HS, Sun JX, Bai WB*. The impact of ultrasonic treatment on blueberry wine anthocyanin color and its In-vitro anti-oxidant capacity. Food Chemistry, 2020, DOI10.1016/j.foodchem.2020.127455. (IF=7.514，1区Top)[7] Sun JX, Chen JL, Mei ZX, Luo ZY Ding LJ, Jiang XW, Bai WB*.Synthesis, structural characterization, and evaluation of cyanidin-3-O-glucoside-loaded chitosan nanoparticles. Food Chemistry, 2020, DOI10.1016/j.foodchem.2020.127239. (IF=7.514，1区Top)[8] Ran GJ, Wu FM, Ni XY, Li XY, Li XS, Liu DL, Sun JX, Xie CF, Yao DS, Bai WB*. A novel label-free electrochemical aptasensor with one-step assembly process for rapid detection of lead (II) ions. Sensors and Actuators B-Chemical, 2020, DOI10.1016/j.snb.2020.128326. (IF=7.46, 1区Top)[9] Li XS, Yao ZL, Yang DC, Jiang XW, Sun JX, Tian LM, Hu J, Wu BY, Bai WB*. Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage. Journal of Hazardous Materials, 2019, DOI10.1016/j.jhazmat.2019.121706. (IF=10.588,1区Top)[10] Sun JX, Li XH, Luo HX, Ding LJ, Jiang XW, Li XS, Jiao R, Bai WB*. Comparative Study on the Stability and Antioxidant Activity of Six Pyranoanthocyanins Based on Malvidin-3-glucoside. Journal of Agricultural and Food Chemistry, 2020,68(9):2783-2794, DOI10.1021/acs.jafc.9b06734. (IF=5.279,1区Top)[11] Li XS, Yao ZL, Jiang XW, Sun JX, Ran GJ, Yang X, Zhao YQ, Yan y, Chen ZS, Tian LM, Bai WB*. Bioactive compounds from Cudrania tricuspidata: A natural anticancer source. Critical Reviews in Food Science and Nutrition, 2020 DOI10.1080/10408398.2018.1541866. (IF=11.176，1区 Top)[12] Chen ZS, Yang DC, Jiang XW, Tian LM, Sun JX, Tian DB, Bai WB*.Final-2 targeted glycolysis mediated apoptosis and autophagy in human lung adenocarcinoma cells but failed to inhibit xenograft in nude mice. Food and Chemical Toxicology, 2019, DOI10.1016/j.fct.2019.04.05. (IF=6.023，2区Top)[13] Li XS, Guo JT, Jiang XW, Sun, JX, Tian LM, Jiao R, Tang YG, Bai WB*. Cyanidin-3-O-glucoside protects against cadmium-induced dysfunction of sex hormone secretion via the regulation of hypothalamus-pituitary-gonadal axis in male pubertal mice. Food and Chemical Toxicology, 2019, DOI:10.1016/j.fct.2019.04.033 (IF=6.023，2区Top)[14] Li X, Lu JL, Sun JX*, Jiang XW, Li XS, Li Y, Jiao R, Tian LM, Bai WB*.Cyanidin-3-O-glucoside promotes progesterone secretion by improving cells viability and mitochondrial function in cadmium-sulfate-damaged R2C cells. Food and Chemical Toxicology, 2019, DOI10.1016/j.fct.2019.03.040. (IF=6.023，2区Top).[15] Li Y, Ran GJ, Lu G, Ni XY, Liu DL, Sun JX, Xie CF, Yao DS*, Bai WB*. Highly Sensitive Label-Free Electrochemical Aptasensor Based on Screen-Printed Electrode for Detection of Cadmium (II) Ions. Journal of the Electrochemical Society, 2019, 166(6): B449-B455 (IF=4.136, 2区Top) [16] Jiang XW, Cao CT, Sun WW, Chen ZS, Li XS, Nahar, L, Sarker, SD, Georgiev, MI, Bai WB*. Scandenolone from Cudrania tricuspidata fruit extract suppresses the viability of breast cancer cells (MCF-7) in vitro and in vivo. Food and Chemical Toxicology, 2019, 126: 56-66 (IF=6.023，2区Top) [17] Sun JX, Luo HX, Li XH, Li XS, Lu YY, Bai WB*. Effects of low power ultrasonic treatment on the transformation of cyanidin-3-O-glucoside to methylpyranocyanidin-3-O-glucoside and its stability evaluation. Food Chemistry, 2019, 276: 240-246 (IF=4.946，2区Top)[18] Tian LM, Tan YS, Chen GW, Wang G, Sun JX, Ou SY, Chen W, Bai WB*. Metabolism of anthocyanins and consequent effects on the gut microbiota. Critical Reviews in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1533517 (IF=11.176，1区)[19] Li XS, Yao ZL, Jiang XW, Sun JX, Ran GJ, Yang X, Zhao YQ, Yan Y, Chen ZS, Tian LM, Bai WB*. Bioactive compounds from Cudrania tricuspidata: A natural anticancer source. Critical Reviews in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1541866 (IF=11.176，1区)[20] Jiang XW, Zhu CJ, Li XS, Sun JX, Tian LM, Bai WB*. Cyanidin-3-O-glucoside at Low Doses Protected against 3-Chloro-1,2-propanediol Induced Testis Injury and Improved Spermatogenesis in Male Rats. Journal of Agricultural and Food Chemistry, 2018, 66(48): 12675-12684 (IF=5.279, 1区)[21] Jiang XW, Li XS, Zhu CJ, Sun JX, Tian LM, Chen W, Bai WB*. The target cells of anthocyanins in metabolic syndrome. Critical Review in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1491022 (IF=11.176, 1区)[22] Yang DC, Jiang XW, Sun JX, Li X, Li XS, Jiao R, Peng ZY, Li YQ, Bai WB*. Toxic effects of zearalenone on gametogenesis and embryonic development: A molecular point of review. Food and Chemical Toxicology, 2018, 119: 24-30 (IF=6.023，2区Top)[23] Liu ZH, Hu YF, Li X, Mei ZX, Wu S, He Y, Jiang, XW, Sun JX, Xiao, JB, Deng, LH*, Bai WB*. Nanoencapsulation of Cyanidin-3- O-glucoside Enhances Protection Against UVB-Induced Epidermal Damage through Regulation of p53-Mediated Apoptosis in Mice. Journal of agricultural and food chemistry, 2018, 66(21): 5359-5367(IF=5.279, 1区)[24] Jiang H, Lai NS, Tang J*,Tian X, Wei FF, Bai WB*, Xu YL. Effect of photo-oxidation on the emissive properties of truxene. Journal of Phottchemistry and Photobiology A-Chemistry, 2018, DOI10.1016/j.jphotochem.2018.09.028.(IF=4.291, 3区)[25] Peng ZY, Jiang XW, Sun JX, Li XS, Hu YF, Tian LM, Bai WB*. Recent Progress in Protective Effect of Flavonoids against Skin Photodamage. Food Science, 2019,40(11):246-253.[26] Ran GJ, Jiang XW, Li HY, Chen JL, Li XS, Sun JX, Bai WB*. Rapid Preparation of Cyanidin-3-glucoside from Mulberry Fruit by Preparative Medium Pressure Liquid Chromatography. Food Science, 2019, 40(3):94-100. [27] Sun JX, Li MW, Zou FY, Bai S, Jiang XW, Tian LM, Ou SY, Jiao R*, Bai WB*. Protection of cyanidin-3-O-glucoside against acrylamide- and glycidamide-induced reproductive toxicity in leydig cells. Food and Chemical Toxicology, 2018, 119: 268-274 (IF=6.023，2区Top)[28] Li X, Guo JT, Liang N, Jiang XW, Song Y, Ou SY, Hu YF, Jiao R*, Bai WB*. 6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells. Frontiers in Pharmacology, 2018, 9, DOI: 10.3389/fphar.2018.00159 (IF=5.81，2区)[29] Li XS, Jiang XW, Sun JX, Zhu CJ, Bai WB*. Recent advances of medical foods in China: The opportunities and challenges under standardization. Food and chemical toxicology, Food and Chemical Toxicology, 2018, 119: 342-354 (IF=6.023，2区Top)[30] Wen LN, Jiang XW, Sun JX, Li X, Li XS, Tian LM, Li Y, Bai WB*. Cyanidin-3-O-glucoside promotes the biosynthesis of progesterone through the protection of mitochondrial function in Pb-exposed rat leydig cells. Food and Chemical Toxicology, 2018, 112: 427-434 (IF=6.023，2区Top)[31] Li X, Jiang XW, Sun JX, Zhu CJ, Li XL, Tian LM, Liu L, Bai WB*. Cytoprotective effects of dietary flavonoids against cadmium-induced toxicity: Mechanisms of dietary flavonoids against cadmium. Annals of the New York Academy of Sciences, 2017 , 1398 (1) :5-19 (IF=5.691 2区)[32] Hu YF, Li ZH, Wang LF, Deng LH, Sun JX，Jiang XW, Zhang Y, Wang YF，Bai WB*. Scandenolone, a natural isoflavone derivative from Cudrania tricuspidata fruit, targets EGFR to induce apoptosis and block autophagy flux in human melanoma cells. Journal of Functional Foods, 2017 , 37 : 229-240. (IF=4.451，1区，Top)[33] He Y, Hu YF, Jiang XW, Chen TF, Ma YT, Wu S, Sun JX, Jiao R, Li X, Deng LH*, Bai WB*. Cyanidin-3-O-glucoside inhibits the UVB-induced ROS/COX-2 pathway in HaCaT cells. Journal of Photochemistry and Photobiology. B, Biology, 2017, 177: 24-31.(IF=6.252，2区)[34] Sun JX, Xu W, Zhu CJ, Hu YF, Jiang XW, Su ZJ, Huang YD, Jiao R *, Bai WB*. Cyanidin-3-O-Glucoside Protects against 1,3-Dichloro-2-Propanol-Induced Reduction of Progesterone by Up-regulation of Steroidogenic Enzymes and cAMP Level in Leydig Cells. Frontiers in Pharmacology. 2016, 7; doi: 10.3389/fphar.2016.00399 (IF=5.81，2区)[35] Hu YF,Ma YT,Wu S,Chen TF,He Y,Sun JX,Jiang XW,Huang YD,Deng LH *, Bai WB*. Protective effect of cyanidin-3-O-glucoside against ultraviolet B radiation-induced cell damage in human HaCaT keratinocytes. Frontiers in Pharmacology.2016; doi: 10.3389/fphar.2016.00301 (IF=5.81，2区)[36] Li MW, Sun JX, Zou FY, Bai S, Jiang XW, Jiao Rui, Ou SY, Zhang H, Su ZJ, Huang YD, Bai WB*. Glycidamide inhibits progesterone production through reactive oxygen species-induced apoptosis in R2C Rat Leydig Cells. Food and Chemical Toxicology. 2016 (IF=6.023, 2区Top)[37] Sun JX, Mei ZX, Tang YJ, Ding LJ, Jiang GC, Zhang C, Sun AD*, Bai WB*. Stability, antioxidant capacity and degradation kinetics of pelargonidin-3-glucoside exposed to power ultrasound at low temperature. Molecules, 2016, 21(9), 1109; doi:10.3390/molecules21091109 (IF=4.411，2区)[38] Sun JX, Li XH, Lin XY, Mei ZX, Li YT, Ding LJ*, Bai WB*. Sonodegradation of Cyanidin-3-glucosylrutinoside: degradation kinetic analysis and its impact on antioxidant capacity in vitro. Journal of the Science of Food and Agriculture, 2016 (IF=5.279，2区Top)[39] Zhang ZH, Zou YY, Wu TG, Huang CH, Pei KH, Zhang GW, Lin XH, Bai WB*, Ou SY*. Chlorogenic acid increased 5-hydroxymethylfurfural formation when heating fructose alone or with aspartic acid at two pH levels. Food Chemistry, 2016, 190: 832–835(IF=7.514，1区top)[40] Song Y, Wen LN, Sun JX, Bai WB*, Jiao R, Hu YF, Peng XC, He Yong, Ou SY*. Cytoprotective mechanism of ferulic acid against high glucose-induced oxidative stress in cardiomyocytes and hepatocytes. Food & Nutriton Research, 2016, 60, 30323. (IF=3.894，2区)[41] Sun JX, Bai S, Bai WB*, Zou FY, Zhang L, Li GQ, Hu YF, Li MW, Yan RA, Su ZJ*, Huang YD. 1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells. Food Chemistry, 2014, 154:330–336 (IF=7.514，1区top)[42] Sun JX, Bai S, Bai WB*, Zou FY, Zhang L, Su ZJ, Zhang QH, Ou SY, Huang YD *, Toxic Mechanisms of 3-Monochloropropane-1,2-Diol on Progesterone Production in R2C Rat Leydig Cells. Journal of Agricultural and Food Chemistry, 2013, 61: 9955-9960 (IF=5.279, 1区top)[43] Bai WB, Xu WT, Huang KL, Yuan YF, Cao SS, Luo YB. A novel common primer multiplex PCR (CP-M-PCR) method for the simultaneous detection of meat species. Food Control, 2009, 20: 366-370 (IF=5.548，2区) 主要著作 [1] 车会莲、马良、白卫滨、邵美丽、李昌模等，食品安全性评价综合实验：中国林业出版社，2014（参编）[2] 贾敬敦，蒋丹平，陈昆松，葛毅强，白卫滨等，食品产业科技创新发展战略，化学工业出版社，95.6万字，2013 （参编）[3] 贾敬敦，孙晓明，陈昆松，葛毅强，白卫滨等, 农业前沿技术与战略新兴产业, 中国农业出版社, 120万字,2011 （参编）[4] 张燕，张辉，孙建霞，白卫滨等，果品的商品化处理与配送，中国劳动社会保障出版社，12.5万字，2012 （副主编）[5] 转基因食品安全与检测技术. 北京：科学出版社，2009，参编 承担课题 主持课题：[1] 广东省重点领域研发计划项目：食品中常见污染物健康危害评估技术，2019-2022，650万；[2] 国家自然科学基金（面上）：超声催陈促进红葡萄酒花色苷衍生物的生成机制，2018-2021，60万；[3] 国家重点研发计划：主要食品全产业链品质质量控制关键技术开发研究课题任务、2016-2020，经费107万元；[4] 广州市产学研协同创新重大专项：岭南特色富含花色苷的果酒、果醋超声催陈关键技术及产品功能评价研究、2017-2020，经费100万元；[5] 国家自然科学基金（面上）：草莓天竺葵素-3-葡萄糖苷对食品中氯丙醇导致细胞氧化应激的营养干预机制，2015-2018，经费82万元；[6] 国家科技支撑计划课题:食品中热反应伴生危害物毒理学检测及风险评估关键技术研究，2012-2014，经费145万元；[7] 国家自然科学基金（青年）: 杨梅花色苷抑制重金属损伤睾丸间质细胞的机制研究, 2012-2015，27万元；[8] 国家863计划项目:优良益生菌高效筛选与应用关键技术子课题，2011-2015，50万元； 发明专利 [1]一种利用多重PCR技术检测转基因番木瓜的方法.国家发明专利，2017，第一完成人（授权并转让）[2]矢车菊素-3-O-葡萄糖苷对1,3-二氯-2-丙醇的生殖毒性的干预作用.国家发明专利，2019，第一完成人（授权）[3]矢车菊素-3-葡萄糖苷对UVB诱导HaCaT细胞损伤的防护作用.国家发明专利，2018，第一完成人（授权）[4]一种稳定包埋花色苷的改性环糊精/羧甲基壳聚糖纳米颗粒的制备方法.国家发明专利，2020，第一完成人（授权）[5]异黄酮类化合物Final-2在制备肺癌细胞葡萄糖转运蛋白表达抑制剂中的应用.国家发明专利，2020，第一完成人（授权）[6]一种利用中压液相色谱从桑葚中制备矢车菊素-3-葡萄糖苷的方法.国家发明专利，2020，第一完成人（授权）[7]镉离子核酸适配体及丝网印刷电极电化学生物传感器.国家发明专利，2019，第一完成人（授权并转让） 讲授课程 食品营养学（本科生）转基因食品安全性评价（本科生）现代食品营养学（研究生）应用现代食品营养学（研究生）食品质量与安全研究进展（研究生） 荣誉奖励 国家级青年人才,省级青年人才 社会职务 担任广东省食品安全分子快速检测工程技术中心主任、广东省食品学会青年工作委员会主任、中国食品科学技术学会第三届青年工作委员会委员，目前担任食品领域Top期刊Critical Reviews in Food Science and Nutrition和Food and Chemical Toxicology杂志的客座主编等。