法世鑫

个人经历 Personal experience 工作经历 教育经历 2022-01 至 今, 西北工业大学, 化学与化工学院, 准聘教授2019-06 至 2021-10, 日本京都大学, 大学院工学研究科合成生物化学专攻, 助教（合作导师：Prof. Tomoki Ogoshi）2018-07 至 2019-05, 日本金沢大学, 纳米生命科学研究所, 助教（合作导师：Prof. Tomoki Ogoshi）2015-10 至 2018-06, 美国Iowa State University, 化学系, 博士后 （导师：赵縯教授） 2009-08 至 2015-07, 中国科学院化学研究所,  理学博士 （导师：王梅祥院士）2005-08 至 2009-07, 中国科学技术大学化学系, 理学学士

教育教学

教育教学 Education and teaching 招生信息 欢迎对本课题组有兴趣的化学、高分子、材料、化工方向的学生加入课题组攻读学位或做毕业设计

荣誉获奖

科学研究 Scientific Research 研究方向：新型功能化的基元分子是超分子组装和识别的物质基础和创新源泉，是实现功能性超分子体系创制和新型材料开发的基础。手性是自然界的本质特征之一。自然界中多种物理过程和生命活动是伴随着对物质手性信息的精准控制完成的。我们关注于手性基元分子（尤其是有机大环分子）的开发及其识别和组装性能的研究。科研项目：国家自然科学基金委面上项目，主持，在研陕西省重点研发计划，主持，在研

科学研究

学术成果 Academic Achievements 20. Keisuke Adachi, Shixin Fa,* Keisuke Wada, Kenichi Kato, Shunsuke Ohtani, Yuuya Nagata, Shigehisa Akine,  TomokiOgoshi,* Adaptive planar chirality of pillar[5]arenes invertible by n-alkane lengths, J. Am. Chem. Soc. 2023, doi.org/10.1021/jacs.3c01019.19. Shixin Fa,// Tan-hao Shi,// Suzu Akama, Keisuke Adachi, Keisuke Wada, Seigo Tanaka, Naoki Oyama, Kenichi Kato, Shunsuke Ohtani, Yuuya Nagata, Shigehisa Akine, Tomoki Ogoshi,* Real-time chirality transfer monitoring from statistically random to discrete homochiral nanotubes, Nat Commun. 2022, 13, 7378.18. Tan-Hao Shi,// Shixin Fa,// Yuuya Nagata, Keisuke Wada, Shunsuke Ohtani, Kenichi Kato, Tomoki Ogoshi,* Discrete chiral organic nanotubes by stacking pillar[5]arenes using covalent linkages, Cell Reports Physical Science, 2022, doi.org/10.1016/j.xcrp.2022.101173.17. Mingqi Wang , Guoxian Zhang , Qing Liu , Mengmeng Wei , Yafeng Ren , Shixin Fa,* Qiuyu Zhang,* Ring -opening of polythiolactones to construct protein-imprinted nanospheres with high recognition and regulation capabilities,  Nanoscale, 2022, 14, 16865.16. Kenichi Kato,// Shixin Fa,// Shunsuke Ohtani, Tan-hao Shi, Albert M. Brouwer,* Tomoki Ogoshi,* Noncovalently bound and mechanically interlocked systems using pillar[n]arenes, Chem. Soc. Rev. 2022, 51, 3648.15. Shixin Fa, Takuya Tomita, Keisuke Wada, Kazuma Yasuhara, Shunsuke Ohtani, Kenichi Kato, Masayuki Gon, Kazuo Tanaka, Takahiro Kakuta, Tada-aki Yamagishi, Tomoki Ogoshi,* CPL on/off control of an assembled system by water soluble macrocyclic chiral sources with planar chirality, Chem. Sci. 2022, 13, 5846.14. Shixin Fa, Masayuki Mizobata, Shusaku Nagano, Kota Suetsugu, Takahiro Kakuta, Tada-aki Yamagishi, Tomoki Ogoshi,* Reversible“on/off”chiral amplification of pillar[5]arene assemblies by dual external stimuli, ACS Nano 2021, 15, 16794.13. Shixin Fa, Keisuke Adachi, Yuuya Nagata, Kouichi Egami, Kenichi Kato, Tomoki Ogoshi,* Pre-regulation of the planar chirality of pillar[5]arenes for preparing discrete chiral nanotubes, Chem. Sci. 2021, 12, 3483.12. Shixin Fa, Kouichi Egami, Keisuke Adachi, Kenichi Kato, Tomoki Ogoshi,* Sequential chiral induction and regulator‐assisted chiral memory of pillar[5]arenes, Angew. Chem. Int. Ed. 2020, 59, 20353.11. Shixin Fa, Yoko Sakata, Shigehisa Akine, Tomoki Ogoshi,* Non‐covalent interactions enable the length‐controlled generation of discrete tubes capable of guest exchange, Angew. Chem. Int. Ed. 2020, 59, 9309.10. Shixin Fa, Masanori Yamamoto, Hirotomo Nishihara,* Ryota Sakamoto,* Kazuhide Kamiya,* Yuta Nishina,* Tomoki Ogoshi,* Carbon-rich materials with three-dimensional ordering at the angstrom level, Chem. Sci. 2020, 11, 5866.9. Shixin Fa, Takahiro Kakuta, Tada-aki Yamagishi, Tomoki Ogoshi,* One-, two-, and three-dimensional supramolecular assemblies based on tubular and regular polygonal structures of pillar[n]arenes, CCS Chem. 2019, 1, 50.8. Shixin Fa, Takahiro Kakuta, Tada-aki Yamagishi, Tomoki Ogoshi,* Conformation and planar chirality of pillar[n]arenes, Chem. Lett. 2019, 48, 1278.7. Shixin Fa, Yan Zhao,* General method for peptide recognition in water through bioinspired complementarity, Chem. Mater. 2019, 31, 4889.6. Shixin Fa, Yan Zhao,* Synthetic nanoparticles for selective hydrolysis of bacterial autoinducers in quorum sensing, Bioorg. Med. Chem. Lett. 2019, 29, 978.5. Shixin Fa, Yan Zhao,* Water‐soluble nanoparticle receptors supramolecularly coded for acidic peptides, Chem. Eur. J. 2018, 24, 150.4. Shixin Fa, Yan Zhao,* Peptide-binding nanoparticle materials with tailored recognition sites for basic peptides, Chem. Mater. 2017, 29, 9284.3. Shi-Xin Fa, Xu-Dong Wang, Qi-Qiang Wang, Yu-Fei Ao, De-Xian Wang, Mei-Xiang Wang,* Multiresponsive vesicles composed of amphiphilic azacalix [4] pyridine derivatives, ACS Appl. Mater. Interface 2017, 9, 10378.2. Shi-Xin Fa, Xiao-Fang Chen, Shuang Yang, De-Xian Wang, Liang Zhao, Er-Qaing Chen,* Mei-Xiang Wang,* Liquid crystalline macrocyclic azacalix[4]pyridine and its complexes with the zinc ion: conformational change from the saddle to flattened shape, Chem. Commun. 2015, 51, 5112.1. Shi-Xin Fa, Li-Xia Wang, De-Xian Wang, Liang Zhao, Mei-Xiang Wang,* Synthesis, structure, and fullerene-complexing property of azacalix[6]aromatics, J. Org. Chem. 2014, 79, 3559.

学术成果

团队信息 Team Information 本课题组依托张秋禹教授团队。张秋禹教授目前担任化学与化工学院院长，承担国家自然科学基金重点项目、面上项目、973前期课题、863重大专项课题、国防基础科研、国防技术基础、多项军品型号配套项目、陕西省自然基金、陕西省科技计划项目、航空基金、航天基金等多项课题的研究。发表科研论文300余篇，获授权发明专利40余项。获得2017年国家科技进步二等奖、陕西省科技奖一等奖1项、二等奖2项、陕西省青年科技奖、教育部霍英东优秀青年教师奖等多项奖励。

综合介绍