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个人简介 教育情况:Education:2011.09-2017.05 浙江大学生工食品学院 博士2015.08-2016.12 新泽西州立(罗格斯)大学药学院 联合培养博士2007.09-2011.06 浙江工业大学生环学院 学士工作经历:Working experience:2020.01-至今 浙江工业大学食品学院 副研究员2017.05-2019.12 浙江工业大学海洋学院 校聘副教授、博士后研究方向: Research interests:近年来在国家自然科学青年基金、浙江省重点研发等项目经费的支持下,申请人主要针对小分子功能营养物质结构繁杂、纯化鉴定困难、功效不明确的问题,进行分离纯化和功能活性评价研究;针对功能营养物质肠道稳定性差、透皮吸收效果差等问题,进行脂质载体、食品大分子载体稳态化设计研究。相关研究内容在国内外食品领域期刊发表论文40余篇,其中第一作者或通讯作者发表JCR1区论文17篇(IF>10,2篇),作为第一发明人申请美国和中国国家发明专利13件,其中授权美国专利1件,中国专利3件。 育人成果 育人成果: Educational achievements:1. 第八届浙江省国际大学生互联网+创新创业大赛,金奖,指导老师2.第三届全国食品专业工程实践训练综合能力竞赛,西南赛区一等奖,指导老师;3.第三届全国食品专业工程实践训练综合能力竞赛,全国赛一等奖,指导老师;4.西湖莼菜核桃蛋白肽口服液,“运河杯”二等奖,指导老师;5.冯思敏(1/1),校级优秀班主任,2018-12 6.冯思敏(1/3),浙江工业大学第三届微课教学比赛,优秀奖,2018-04 7.冯思敏(1/1), 食品科学与工程学院教师教学创新大赛,一等奖,2021-11 教学与课程 教学与课程:Teaching & course:主讲本科生课程:《食品工程原理》、《食品分析实验》主讲研究生课程:《科技论文写作》教改项目:1.食品分析实验“线上、线下”协同教学创新与实践,创新实验项目,20192.新工科背景下实验课程“虚实”协同教学新模式——以《食品分析实验》为例,校教改项目,2022参编教材:1.副主编编辑出版《食品分析与安全检测技术》2.参编《现代食品分离技术》。 科研项目 科研项目:Project: 1.国家自然科学基金青年项目,基于空间定位的植物甾醇纳米乳液稳定机制研究,2019-01至2021-12,结题,主持; 2.浙江省重点研发子课题,功能提取物的危害物高效脱除提质及功能因子大分子载体稳态化复配,2021-01至2024-6,在研,主持; 3.浙江省重点研发子课题,大宗农产品高效提取技术研究和产品开发,2019-01至2022-06,在研,主持;4.浙江省重点研发子课题,糯山药贮运过程中功能营养物变化研究,2019-08至2022-7,在研,主持; 5.浙江省公益项目,不同刚性石斛黄酮纳米脂质体的构建及其降尿酸功效研究,2022-01至2024-12,在研,主持;6.中国博士后面上基金,基于不同C3支链植物甾醇刚性调控的纳米脂质体稳定机制研究,2020-08至2021-12,结题,主持;7.中国博士后面上基金,基于微观空间定位的植物甾醇纳米乳液增溶增效机理研究,2017-05至2019-02,5万,结题,主持; 8.浙江省重点研发课题,天然特色森林资源健康功能产品深度开发与应用研究,2019.01至2022.06,科技/省部级,在研,参与2/19;9.浙江省重点研发子课题,莼菜多糖三降健康食品研发,2017.01至2020.12,结题,参与2/3;10.企业横向课题,农产品中结合态植物甾醇的分离鉴定研究,2021.07至2022.07,在研,主持; 科研成果 主要研究与成果:Main research area and publications:近年来在国内外期刊发表SCI/EI等论文40余篇其中第一作者或通讯作者发表JCR1区论文30篇(IF>10,4篇)。近3年代表性论文有: Simin Feng(冯思敏); Sijie Wu; Fei Xie; Chung S. Yang*; Ping Shao*; Natural compounds lower uric acid levels and hyperuricemia: Molecular mechanisms and prospective, Trends in food science & technology, 2022, 123: 87-102.(IF=16.002,JCR1 区)Simin Feng(冯思敏); LiLing Wang; Ping Shao; Baiyi Lu; Yanfei Chen; Peilong Sun*; Simultaneous analysis of free phytosterols and phytosterol glycosides in rice bran by SPE/GC-MS, Food Chemistry, 2022, 387: 132742. (IF=9.231,ZJUTTOP 100, JCR1 区)Sui M, Simin Feng(冯思敏)*, Gaodan Liu, Bilian Chen, Zhenhao Li, Ping Shao*. Deep eutectic solvent on extraction of flavonoid glycosides from Dendrobium officinale and rapid identification with UPLC-triple-TOF/MS.Food Chemistry, 2022, 401:134054. (IF=9.231,ZJUTTOP 100, JCR1 区)Feng Simin(冯思敏), LiLing Wang, Ping Shao, et. al. A review on chemical and physical modifications of phytosterols and their influence on bioavailability and safety[J]. Critical Reviews in Food Science and Nutrition, 2021, DOI: 10.1080/10408398.2021.1888692 (IF=11.208, JCR1 区)Feng Simin(冯思敏), Tarun Belwal, Li Li, et. al. Phytosterols and their derivatives: Potential health-promoting uses against lipid metabolism and associated diseases, mechanism, and safety issues[J]. Comprehensive Reviews in Food Science and Food, 2020, 19(4): 1243-1267 (IF=15.786, JCR1 区) Feng Simin(冯思敏), Yuxin Sun, Dan Wang, et. al. Effect of adjusting pH and chondroitin sulfate on the formation of curcumin-zein nanoparticles: Synthesis, characterization and morphology[J]. Carbohydrate Polymers, 2020, 250:116970 (IF=10.723, JCR1 区)Feng Simin(冯思敏), Wang Lei, Belwal Tarun, et. al. Phytosterols extraction from hickory (Carya cathayensis Sarg.) husk with a green direct citric acid hydrolysis extraction method, Food Chemistry, 2020, 315:126217 (IF=7.514, ZJUTTOP 100, JCR1 区)Feng Simin(冯思敏)*, Wang Zhangtie, Zhao Jinjina, et. al. Fabrication and characterization of water-soluble phytosterol ester nanodispersion by emulsification-evaporation combined ultrasonic method, Journal of Food Engineering, 2020, 276:109895 (IF=5.279, ZJUTTOP 100, JCR1 区)Feng Simin(冯思敏), Jiadan Yan, Dan Wang, et. al. Preparation and characterization of soybean protein isolate/pectin-based phytosterol nanodispersions and their stability in simulated digestion[J]. Food Research International, 2021, DOI: 10.1016/j.foodres.2021.110237 (IF=6.475 JCR1 区)Feng Simin(冯思敏), Gan Ling, Yang Chung S.,et. al. Effects of stigmasterol and beta-sitosterol on nonalcoholic fatty liver disease in a mouse model: a lipidomic analysis, Journal of agricultural and Food Chemistry, 2018, 66 (13): 3417-3425 (IF=5.279, ZJUTTOP 100, JCR1 区) Feng Simin(冯思敏), Dan Wang, Ling Gan, et. al. Preparation and characterization of zein/pectin-based phytosterol nanodispersions and kinetic study of phytosterol release during simulated digestion in vitro[J].LWT-Food Science and Technology,2020,128:109446 (IF=4.952, JCR1 区)Feng Simin(冯思敏), Xinying Zheng, Di Luan, et. al. Preparation and characterization of zein-based phytosterol nanodispersions fabricated by ultrasonic assistant anti-solvent precipitation, LWT-Food Science and Technology, 2019,107,138-144 (IF=4.952, JCR1 区)Feng Simin(冯思敏), Zhuqing Dai, Anna Liu, et. al. Intake of stigmasterol and beta-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet, Biochimica et biophysica acat-molecular and cell biology of lipids, 2018, 1863 (10): 1274-1284 (IF=4.519, JCR1 区)Feng Simin(冯思敏) ,Di Luan, Ning Ke, et. al. Ultrafiltration isolation, hypoglycemic activity analysis and structural characterization of polysaccharides from Brasenia schreberi, International journal of biological macromolecules, 2019, 135:141-151(IF=5.162, JCR1 区)授权专利:Patents:作为第一发明人申请美国和中国国家发明专利13件,其中授权美国专利1件,中国专利3件:1.冯思敏; 郑欣盈; 邵平; 孙培龙; 栾迪; 一种玉米醇溶蛋白负载植物甾醇的纳米乳液的制备方法,2020-1-14,中国,ZL201810462755.1. 授权2.冯思敏; 毛水芳; 宁可; 邵平; 孙培龙; 蒋丽刚; 一种莼菜体外多糖胶的物理分离方法,2020-12-11,中国,ZL201810026177.7. 授权3.冯思敏;孙培龙;王章铁;王丹;邵平;一种利用酶标仪准确检测植物甾醇酯含量的方法,2021-8-3,中国,ZL201910085592.4. 授权4.Simin Feng(冯思敏), Peilong Sun, Ping Shao, Jiadan Yan, Dan Wang, Yuxin Sun. Preparation method of water-soluble phytosterol nano dispersion system with enterally targeting release function,2021-05,美国,US11058693,授权荣誉与奖项:Honors and awards1.冯思敏(2/9),海藻多糖增值加工关键技术及产业化应用,浙江省科学技术进步奖二等奖,20212.冯思敏(3/8),功能营养物包埋载体设计技术及其健康产品应用,商业联合会科学技术奖一等奖,2018 3.冯思敏(6/10),海藻多糖高值化加工新技术及产业化应用,商业联合会科学技术奖一等奖,2017 社会服务 学术兼职: Academic concurrent jobs: 担任浙江省食品学会理事,浙江食品学会青年委员会委员,浙江营养学会科普宣传委员会委员;中国轻工业食品大分子资源加工技术重点实验室办公室主任,Journal of Food Engineering、Food&Function等杂志的审稿专家。浙江华才检测技术有限公司博士后。