靳水林

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English Homepage 新建主栏目 个人新闻 新闻标题 欢迎马至成、杨鸣宇、王思璇加入团队，攻读博士学位 发布时间 2023-08 预祝一切顺利! 新闻标题 祝贺杨博、何田韵、阙千荟通过硕士答辩 发布时间 2023-06 预祝前途一片光明！ 新闻标题 祝贺亓晶博士通过博士答辩，获得博士学位 发布时间 2023-04 恭喜，再接再厉！ 新闻标题 欢迎博士生肖舒彤，盛琼宇加入课题组 发布时间 2022-09-30 预祝学业顺利 新闻 新闻标题 欢迎博士生花娇，阚裕隆加入课题组 发布时间 2021-09 预祝学业顺利 新闻标题 欢迎硕士生杨博，阙千荟，何田韵加入课题组 发布时间 2021-09 新闻标题 祝贺方子旋、陈君源通过学士学位论文答辩 发布时间 2021-06 预祝学业有成，一切顺利。 新闻标题 欢迎硕士生赵梓岑，盛琼宇，崔博森加入课题组 发布时间 2020-09-10 新闻标题 祝贺张丽颖，边嘉琳，刘贝贝通过硕士学位论文答辩 发布时间 预祝将来事业顺利，学业有成！ 新闻标题 祝贺许寅，李泽琛，杜美霖通过学士论文答辩 发布时间 祝未来事业顺利，学业有成！ 新闻标题 预祝王楠美国科研、生活顺利！ 发布时间 2019-12-04 新闻标题 欢迎硕士生花娇、周阳加入课题组 发布时间 2019-09-01 新闻标题 祝贺张博洋，韩一辉，苏晓曼硕士毕业答辩 发布时间 2019-07-10 元素路径: body > p > img 新闻标题 欢迎明尼苏达大学管卫华教授访问课题组 发布时间 2019-07-09 新闻标题 欢迎美国统计学会士、德州大学武虎林教授访问课题组 发布时间 2019-06-28 新闻标题 祝贺王卓通过博士答辩！ 发布时间 2019-06-19 新闻标题 欢迎亓晶加入课题组 发布时间 2019-03-01 期待未来科研之路顺利，收获满满！ 新闻标题 祝贺刘桂友博士发表PNAS文章 发布时间 2019-02-26 新闻标题 2018哈工大教师节颁奖 发布时间 2018-09-09 新闻标题 欢迎张丽颖，边嘉琳硕士加入课题组编辑 发布时间 2018-09-05 新闻标题 高等学校大学数学教材建设研讨会在哈工大顺利召开 发布时间 2018-07-21 详见：http://today.hit.edu.cn/node/57900 新闻标题 受课题组邀请，明尼苏达大学管卫华教授访问数学系 发布时间 2018-07-12 新闻标题 受课题组邀请，哈佛大学林希虹教授访问哈工大 发布时间 2018-07-08 新闻标题 祝贺王楠、吴德亮硕士顺利毕业 发布时间 2018-07-08 新闻标题 祝贺刘桂友博士PNAS论文发表 发布时间 2017-09-05 恭喜恭喜！ 新闻标题 欢迎张博洋，韩一辉硕士加入课题组 发布时间 2017-09-04 热烈欢迎！ 新闻标题 欢迎中兴副总裁吕阿斌访问数学系！ 发布时间 20170712 吕阿斌，中兴通讯副总裁，中兴飞流CEO，大数据系统计算技术国家工程实验室董事长。 新闻标题 祝贺张秀蕊顺利硕士毕业！ 发布时间 20170707 预祝未来工作顺利，生活幸福！ 新闻标题 欢迎管卫华教授访问哈工大 发布时间 20170704 受课题组邀请，明尼苏达大学管卫华教授访问课题组，并开设《数据统计分析及其应用》课程。 http://today.hit.edu.cn/news/2017/06-30/1145253160RL0.htm 新闻标题 受课题组邀请，University of Cincinnati大学刘敦罡教授访问课题组 发布时间 20170608 刘敦罡，博士毕业于美国罗格斯大学(Rutgers University)，耶鲁大学博士后，现为美国辛辛那提大学商学院助理教授，在数据meta分析，置信分布推断以及有序数据分析等方向做出杰出工作。在JASA、Biometrics等期刊发表多篇重要论文。http://math.hit.edu.cn/news.do?cmd=show&id=2328 新闻标题 第一届教学节金牌授课教师 发布时间 2017-06-07 新闻标题 祝贺王卓博士BMC Bioinformatics论文接收 发布时间 2017-03 祝贺！! 新闻标题 祝贺刘桂友博士PNAS论文发表 发布时间 2017-02 祝贺！! 新闻标题 欢迎王楠，吴德亮加入课题组 发布时间 2016-09-05 热烈欢迎！ 新闻标题 受课题组邀请，捷克工业大学数学系主任Jan Hamhalter教授访问我校 发布时间 2016-07-19 Jan Hamhalter, 捷克工业大学数学系主任，资深教授。在量子测量，算子代数，理论物理等方面有着杰出的工作。详见：http://math.feld.cvut.cz/hamhalte/ 新闻标题 恭喜哈工大数学研究院成立 发布时间 2016-07-18 数学研究院成立，希望哈工大数学学科更上一层楼！ 新闻标题 受课题组邀请，明尼苏达大学管卫华老师访问哈工大！ 发布时间 2016-07-12 管卫华，本科毕业于北京大学，博士毕业于University of Michigan，现为University of Minnesota副教授。在《Nature》、《PNAS》、《Biometrika》等国际著名期刊发表生物统计相关学术论文50余篇。现为美国统计学会会员、美国人类基因组学会会员。非常荣幸邀请到管卫华老师，开设《数据统计分析及其应用》课程！详见： http://today.hit.edu.cn/news/2016/07-06/1854356170RL0.htm 新闻标题 祝贺王佳顺利通过硕士答辩，祝贺祝饶毅通过本科答辩！ 发布时间 2016-07-05 祝福生活一帆风顺，事业蒸蒸日上！！ 新闻标题 受课题组邀请，哈佛大学董献军访问我校 发布时间 2016-04-20 董献军，哈佛大学讲师，主要研究生物信息，生物统计。已在《Nature》《Cell》《Genome Biology》《NAR》等著名期刊发表论文二十余篇。欢迎访问哈工大。详见：http://www.scherzerlaboratory.org/members/index.html 基本信息 名称 靳水林，河北邢台人，哈尔滨工业大学数学学院教授，国家级高层次人才。数学、统计学博士生导师。哈尔滨工业大学青年科学家工作室负责人。 主持国家自然科学基金面上项目、青年基金项目、863项目、黑龙江省杰青等项目，入选哈工大理学创新培育计划；参与国家“生物安全”重大科技专项课题等。获得黑龙江自然科学一等奖。 教育经历 名称 时间 教育经历 学位 2009年9月-2012年9月 哈尔滨工业大学 博士后 2003年9月-2009年6月 吉林大学 博士 1999年9月-2003年6月 吉林大学 学士 工作经历 名称 时间 工作经历 任职 2019年12月-现在 哈尔滨工业大学 教授 2017年4月-现在 哈尔滨工业大学 博士生导师 2013年12月-2019年12月 哈尔滨工业大学 副教授 2009年6月-2013年12月 哈尔滨工业大学 讲师 2019年3月-2019年3月 加州大学欧文分校(UCI) 访问学者 2018年12月-2019年2月 哈佛大学 访问学者 2013年4月-2014年4月 哈佛大学 访问学者 2015年10月-2015年11月 明尼苏达大学 访问学者 主要任职 名称 现担任数学评论(Math Review)评论员，德国数学文摘(Zentralblatt Math)评论员，多个杂志通讯评审，国家高层次人才会评、函评专家，自然科学基金通讯评审，教育部自然科学奖通讯评审，教育部学位论文通讯评审，中国高校创新创业教育研究中心专家等。 讲授课程 名称 2010年秋工科数学分析Ⅰ 180学时 2011年春工科数学分析Ⅱ 180学时 2012年春工科数学分析Ⅱ 180学时 2014年秋工科数学分析Ⅰ 84学时 2015年春工科数学分析Ⅱ 168学时 2016年秋微积分Ⅱ 176学时 2017年春 数据统计分析及其应用 16学时 2017年秋工科数学分析Ⅰ 88学时 2018年春微积分 176学时 2019年秋微积分 88学时 2020年春微积分 82学时 研究生共建课程： 2016夏 数据统计分析及其应用 2017夏 数据统计分析及其应用 境外知名学者课程： 2014夏, 2016夏 算子概率论及其应用 教育、教学成果 名称 2020哈工大招生工作先进个人 2018第十二届教学优秀奖 一等奖 2017年度哈尔滨工业大学金牌授课教师 2016第六届青年教师教学基本功竞赛 二等奖 2016年大一年度创新创业项目计划 二等奖 国家精品在线课程主讲教师 科研项目 名称 1. 帕金森病相关的长链非编码RNA识别与功能分析方法研究 国家自然科学基金面上项目 主持 2. 算子代数独立性的等价描述 国家自然科学基金青年基金 主持 3. 算子代数独立性与R.Curto公开问题 黑龙江自然科学基金 主持 4. 水污染诱发类癌症的致病机理研究—基于长链非编码RNA预测模型与算法 城市水资源与水环境国家重点实验室开放课题 主持 5. 基于RNA-Seq分析的帕金森疾病机理研究 哈尔滨工业大学理学创新培育计划 主持 6. 生物大数据表述索引、搜索与存储访问关键技术研发 国家863重大项目 子课题负责人 7. 高等级病原微生物实验室信息管理关键技术与系统研发 国家重点研发计划 参与 8. 基于生物数据融合的致病microRNA识别方法研究 国家自然科学基金 参与 论文期刊 名称 2023 Yang Zhou, Qiongyu Sheng, Jing Qi, Jiao Hua, Bo Yang, Lei Wan, Shuilin Jin*. Accurate integration of multiple heterogeneous single-cell RNA-seq data sets by learning contrastive biological variation, Genome Research, 2023, 33(5): 750-762. 2022 Jing Qi, Qiongyu Sheng, Yang Zhou, Jiao Hua, Shutong Xiao, Shuilin Jin*. scMTD: a statistical multidimensional imputation method for single-cell RNA-seq data leveraging transcriptome dynamic information, Cell & Bioscience, 2022, 12(1): 1-15. 2021 Jing Qi, Yang Zhou, Zicen Zhao, Shuilin Jin*. SDImpute: A statistical block imputation method based on cell-level and gene-level information for dropouts in single-cell RNA-seq data, PLoS Computational Biology, 2021, 17(6): e1009118. Pingping Wang, Xiyun Jin, Wenyang Zhou, Meng Luo, Zhaochun Xu, Chang Xu, Yiqun Li, Kexin Ma, Huimin Cao, Yan Huang, Guangfu Xue, Shuilin Jin, Huan Nie, Qinghua Jiang. Comprehensive analysis of TCR repertoire in COVID-19 using single cell sequencing, Genomics, 2021, 113(2): 456-462. Jing Qi, Yang Zhou, Jiao Hua, Liying Zhang, Jialin Bian, Beibei Liu, Zicen Zhao, Shuilin Jin*. The scRNA-seq expression profiling of the receptor ACE2 and the cellular protease TMPRSS2 reveals human organs susceptible to SARS-CoV-2 infection, International Journal of Environmental Research and Public Health, 2021, 18(1): 284. 2020 Nan Wang , Jun Zhang , Li Xu, Jing Qi , Beibei Liu, Yiyang Tang, Yinan Jiang, Liang Cheng, Qinghua Jiang, Xunbo Yin, Shuilin Jin*. A novel estimator of between-study variance in random-effects models, BMC Genomics, 2020, 21(1): 149. Ruiyu Xiao, Guoshan Lu, Wanqian Guo, Shuilin Jin*. NDRindex: a method for the quality assessment of single-cell RNA-Seq preprocessing data, BMC bioinformatics, 2020, 21(16): 1-9. Yating He, Haihua Zhang, Tao Wang, Zhifa Han, Qing-bin Ni, Kun Wang, Longcai Wang, Yan Zhang, Yang Hu, Shuilin Jin, Bao-liang Sun, Guiyou Liu. Impact of serum calcium levels on Alzheimer’s disease: a Mendelian randomization study, Journal of Alzheimer's Disease, 2020, 76(2): 713-724. Longcai Wang, Yanchun Qiao, Haihua Zhang, Yan Zhang, Jiao Hua, Shuilin Jin, Guiyou Liu. Circulating vitamin D levels and Alzheimer’s disease: a Mendelian randomization study in the IGAP and UK Biobank, Journal of Alzheimer's Disease, 2020, 73(2): 609-618. 2019 Guiyou Liu, Yang Hu, Zhifa Han, Shuilin Jin*, Qinghua Jiang*. Genetic variant rs17185536 SIM1 gene expression in human brain hypothalamus, Proceedings of the National Academy of Sciences: PNAS, 2019, 116 (9): 3347-3348. Zhuo Wang, Shuilin Jin*, Chiping Zhang*, A method based on differential entropy-like function for detecting differentially expressed genes across multiple conditions in RNA-Seq studies, Entropy, 2019, 21(3): 242. Nan Wang, Ying Zhang, Li Xu, Shuilin Jin*, Relationship between Alzheimer's disease and the immune system: A meta-analysis of differentially expressed genes, Frontiers in Neuroscience, 2019, 12: 1026. 2018 Zhifa Han, Rui Tian, Peng Ren, Wenyang Zhou, Peng Wang, Shuilin Jin*, Qinghua Jiang*, Parkinson's disease and Alzheimer's disease: a Mendelian randomization study, BMC medical genetics, 2018, 19 (1), 215 Guiyou Liu, Shuilin Jin, Yang Hu, Qinghua Jiang*. Disease status affects the association between rs4813620 and the expression of Alzheimers disease susceptibility gene TRIB3. PNAS, 115(45), E10519-E10520 Zhifa Han#, Tao Wang#, Rui Tian, Wenyang Zhou, Pingping Wang, Peng Ren, Jian Zong, Yang Hu, Shuilin Jin*, Qinghua Jiang*. BIN1 rs744373 variant is significantly associated with Alzheimer’s disease in Caucasian but not East Asian populations. 2018. BMC Bioinformatics. (Accepted) Weiyue Ding, Li Xu, Lejun Zhang, Zhijie Han, Qinghua Jiang, Z Wang, Shuilin Jin*, Meta-analysis of association between TCF7L2 polymorphism rs7903146 and type 2 diabetes mellitus, BMC medical genetics, 19 (1), 38 Guiyou Liu, Y Zhao, Shuilin Jin, Yang Hu, Tao Wang, Rrui Tian, Zhifa Han, D Xu, Qinghua Jiang, Circulating vitamin E levels and Alzheimer’s disease: a Mendelian randomization study, Neurobiology of aging, 2018 Guiyou Liu, Tao Wang, Rrui Tian, Yang Hu, Zhifa Han, P Wang, W Zhou, P Ren, J Zong, Shuiiln Jin*, Qinghua Jiang*, Alzheimer’s Disease Risk Variant rs2373115 Regulates GAB2 and NARS2 Expression in Human Brain Tissues, Journal of Molecular Neuroscience, 2018, 1-7 2017 Yang Hu, Shuilin Jin, Liang Cheng, Guiyou Liu, and Qinghua Jiang Autoimmune disease variants regulate GSDMB gene expression in human immune cells and whole blood, Proceedings of the National Academy of Sciences of the United States of America: PNAS, 2017.Zhuo Wang*, Shuilin Jin*, Guiyou Liu*, Xiurui Zhang, Nan Wang, Deliang Wu, Yang Hu, Chiping Zhang*, Qinghua Jiang*, Li Xu*, Yadong Wang*, DTWscore:differential expression and cell clustering analysis for time-series single-cell RNA-seq data, BMC Bioinformatics, 2017, 18:270. Guiyou Liu, Yang Hu, Shuilin Jin, Qinghua Jiang*, Genetic variant rs763361 regulates multiple sclerosis CD226 gene expression，Proceedings of the National Academy of Sciences of the United States of America: PNAS, 2017, 114(6): E906-E907. Jan Hamhalter, Shuilin Jin*, Operational independence and tensor products of C*-algebras, Journal of Mathematical Physics, 2017, 58(3):032303. Jiajie Peng, Kun Bai, Xuequn Shang, Guohua Wang, Hansheng Xue, Shuilin Jin, Liang Cheng, Yadong Wang, Jin Chen, Predicting disease-related genes using integrated biomedical networks, BMC Genomics, 2017, 18(Suppl 1): 1043. Yang Hu, Likun Zheng, Liang Cheng, Ying Zhang, Weiyang Bai, Wenyang Zhou, Tao Wang, Zhifa Han, Jian Zong, Shuilin Jin, Jun Zhang, Guiyou Liu, Qinghua Jiang, GAB2 rs2373115 variant contributes to Alzheimer@#%s disease risk specifically in European population, Journal of the Neurological Sciences, 2017, 375: 18-22. 2016 Shuilin Jin, et al. The complexity of promoter regions based on a vector topological entropy. Current Bioinformatics, 2016, 11. Yang Hu, Zhou W, Ren J, Dong L, Wang Y, Shuilin Jin*, Cheng L.Annotating the Function of the Human Genome with Gene Ontology and Disease Ontology. Biomed Res Int. 2016;2016:4130861. Qinghua Jiang*, Shuilin Jin*, Yongshuai Jiang, Mingzhi Liao, Rennan Feng, Liangcai Zhang, Guiyou Liu, Junwei Hao. Alzheimer@#%s disease variants with the genome-wide significance are significantly enriched in immune pathways and active in immune cells,Molecular Neurobiology, 54(1), 594-600. Guiyou Liu, Yang Hu, Shuilin Jin, Fang Zhang, Qinghua Jiang, Junwei Hao. Cis-eQTLs regulate reduced LST1 gene and NCR3 gene expression and contribute to increased autoimmune disease risk. Proceedings of the National Academy of Sciences of the United States of America:PNAS. 113, 42, E6321–E6322. Guoqiang Wan, Wenyang Zhou, Yang Hu, Rui Ma, Shuilin Jin, Guiyou Liu, and Qinghua Jiang. Transcriptional Regulation of lncRNA Genes by Histone Modification in Alzheimer’s Disease. 2016 (2016), 3164238. Wanqian Guo, Zizeng Yang, Juanshan Du, Renli Yin, Xianjiao Zhou, Shuilin Jin and Nanqi Ren. Degradation of sulfadiazine in water by a UV/O3 process: performance and degradation pathway. RSC Adv., 2016,6, 57138-57143 2015 Qinghua Jiang,Jixuan Wang,Xiaoliang Wu,Rui Ma,Tianjiao Zhang,Shuilin Jin, Zhijie Han, Renjie Tan, Jiajie Peng, Guiyou Liu, Yu Li, Yadong Wang. LncRNA2Target: a database for differentially expressed genes after lncRNA knockdown or overexpression，Nucleic Acids Research,2015, 43(D1):D193-D196. Qinghua Jiang,Rui Ma,Jixuan Wang,Xiaoliang Wu,Shuilin Jin,Jiajie Peng, Renjie Tan, Tianjiao Zhang, Yu Li, Yadong Wang, LncRNA2Function: A comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data, BMC Genomics, 2015, 16：S2. 2014 Shuilin Jin, Renjie Tan, Qinghua Jiang, Li Xu, Jiajie Peng, Youg Wang andYadong Wang A generalized topological entropy for analyzing the complexity of DNA sequences, PLOS One 2014, 9(2): e88519. Li Xu，Shuilin Jin，Guisheng Yin, A track association algorithm based on the weighted association graph for laser triangulation sensors, Optik, 2014, 125(20): 5973-5977. Li Xu，Shuilin Jin，Guisheng Yin，A track association algorithm based on leader-follower on-line clustering in dense target environments, Radioengineering, 2014, 23(1):259-265. Li Xu, Shuilin Jin, Guisheng Yin,Bidirectional-paralleled flexible graphplan, Journal of Computational and Theoretical Nanoscience, 2014, 11(10):2190-2193. 2013 Shuilin Jin and Li Xu. Independences of operator algebras and joint spectrum of operators. Linear and Multilinear Algebra. 2013, 61(5): 565-572. Qinghua Jiang, Guohua Wang, Shuilin Jin, Yu Li, Yadong Wang Predicting human microRNA-disease associations based on support vector machine, International Journal of Data Mining and Bioinformatics. 2013, 8(3): 282-293. Shuilin Jin and Li Xu. On Curto’s open problem. Journal of Mathematical Analysis and Applications. 2013, 1(405): 342-344. Shuilin Jin, Li Xu and Qinghua Jiang. Joint spectrum and joint distribution. Complex Analysis and Operator Theory. 2013, 7: 1869-1875. Li Li, Shuilin Jin and Li Yang. Large time behavior of the Vlasov-Poisson-Boltzmann system. Abstract and Applied Analysis. 2013, 2013: 632903. Li Xu, Shuilin Jin and Guisheng Yin. Track fusion via track filter in dense sensor environments. Measurement. 2013, 46(10): 3871-3875. 2012 Shuilin Jin, Li Xu, Qinghua Jiang and Li Li. Conditions equivalent to C* independence Studia Mathematica. 2012, 211(3):191-197. Shuilin Jin and Li Xu. The entanglement of independent quantum systems. Advances in Mathematical Physics. 2012, 2012: 104856. Shuilin Jin, Qinghua Jiang, Yadong Wang and Guangren Duan. On joint spectrum of infinite direct sums. Operators and Matrices. 2012, 6(3): 529-533. Shuilin Jin, Li Xu, Qinghua Jiang and Guangren Duan. A joint spectral characterization of C* independence. Infinite Dimensional Analysis Quantum Probability and Related Topics. 2012, 15(2): 1250013. 出版物 出版物名称 全国大学生数学竞赛复习全书 作者 尹逊波，靳水林，郭玉坤 出版时间 2014-04-01 出版社 哈尔滨工业大学出版社 简单介绍 奖项成果 奖项名称 哈尔滨市科技进步三等奖 获奖时间 2017 完成人 所获奖项 简单介绍 招生信息 名称 研究方向：计算系统生物学，生物统计学，生物信息学。 主要围绕疾病相关的各种高通量数据，开展数据建模、统计分析等工作， 每年招收博士研究生1-2名，硕士研究生2-3名。 如果对以上研究方向有兴趣，欢迎联系我！ email：jinsl@hit.edu.cn 学生信息 名称 在读研究生： 2018级博士 王楠 2019级博士 亓晶 Najeeb Najmi 2020级博士 周阳 Tun Lin Aung 2021级博士 花娇 阚裕隆 2020级硕士 赵梓岑 盛琼宇 崔博森 2021级硕士 杨博 阙千荟 曹荣阳 何田韵 在读本科生： 2018级本科 肖舒彤 李昊隆 李庚晨 王为灏 张鑫渊 毕业学生： 2014级硕士 王佳 工作单位：中国移动河南郑州公司 2015级硕士 张秀蕊 工作单位：格力空调 2016级硕士 吴德亮 工作单位：中兴通讯 王楠 工作单位：哈尔滨工业大学（博士） 2012级本科 祝饶毅 工作单位：浙江省江山中学 2014级本科 徐浩 工作单位：北京快手 吴壮志 工作单位：某部队，程远坤 工作单位：英国攻读硕士学位 2014级博士 王卓 （副导师） 工作单位：深圳香港中文大学 2016级博士 刘桂友（副导师）工作单位：首都医科大学 2017级硕士 张博洋 工作单位：北京京东 韩一辉 工作单位：中兴飞流 2015级本科 田晶明 工作单位：某部队 2016级本科 李泽琛 工作单位：出国攻读硕士学位，许寅：中科院攻读研究生，葛小宇：上海交通大学攻读研究生，杜美霖 2018级硕士 张丽颖：杭州，边嘉琳：北京金山云 2019级硕士 花娇：哈工大读博 2017级本科 肖瑞宇：哈工大硕士 徐旭：哈工大硕士 2017级本科 方子旋：上海交大硕士 陈君源 Background 名称 Shuilin Jin is Professor of Mathematics at Harbin Institute of Technology. My research interest covers computational biology, biostatistics, and operator probability theory. And my team are good at machine learning, statistical learning and AI to solve related big data problems. If you are interested in the above research directions, please do not hesitate to contact me! Email:jinsl@hit.edu.cn Education 名称 2003.9–2009.6 Ph.D. Mathematics, Jilin University. Dissertation: Independence of Operator Algebras and Joint Spectrum of Operators. 1999.9–2003.6 B.S. Probability and Statistics, Jilin University. Dissertation: Hp Spaces Employment 名称 2017.04-Present Ph.D. Supervisor, Harbin Institute of Technology. 2013.12–Present Associate Professor, Harbin Institute of Technology. 2009.6–2013.12 Assistant Professor, Harbin Institute of Technology. 2013.4-2014.4 Vistiting Scholar, Harvard University. 2015.10-2015.11 Vistiting Scholar, University of Minnesota. Publications 名称 2022 Hao Liu, Danxiu Li, Lina Sun, Hongqiang Qin, Ahui Fan, Lingnan Meng, Ramona Graves-Deal, Sarah E Glass, Jeffrey L Franklin, Qi Liu, Jing Wang, Timothy J Yeatman, Hao Guo, Hong Zong, Shuilin Jin, Zhiyu Chen, Ting Deng, Ying Fang, Cunxi Li, John Karijolich, James G Patton, Xin Wang, Yongzhan Nie, Daiming Fan, Robert J Coffey, Xiaodi Zhao, Yuanyuan Lu, Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression, Molecular Cancer, 2022, 21(1): 1-18. 2021 Jing Qi, Yang Zhou, Zicen Zhao, Shuilin Jin*. SDImpute: A statistical block imputation method based on cell-level and gene-level information for dropouts in single-cell RNA-seq data, PLoS Computational Biology, 2021, 17(6): e1009118. Pingping Wang, Xiyun Jin, Wenyang Zhou, Meng Luo, Zhaochun Xu, Chang Xu, Yiqun Li, Kexin Ma, Huimin Cao, Yan Huang, Guangfu Xue, Shuilin Jin, Huan Nie, Qinghua Jiang. Comprehensive analysis of TCR repertoire in COVID-19 using single cell sequencing, Genomics, 2021, 113(2): 456-462. Jing Qi, Yang Zhou, Jiao Hua, Liying Zhang, Jialin Bian, Beibei Liu, Zicen Zhao, Shuilin Jin*. The scRNA-seq expression profiling of the receptor ACE2 and the cellular protease TMPRSS2 reveals human organs susceptible to SARS-CoV-2 infection, International Journal of Environmental Research and Public Health, 2021, 18(1): 284. 2020 Nan Wang , Jun Zhang , Li Xu, Jing Qi , Beibei Liu, Yiyang Tang, Yinan Jiang, Liang Cheng, Qinghua Jiang, Xunbo Yin, Shuilin Jin*. A novel estimator of between-study variance in random-effects models, BMC Genomics, 2020, 21(1): 149. Ruiyu Xiao, Guoshan Lu, Wanqian Guo, Shuilin Jin*. NDRindex: a method for the quality assessment of single-cell RNA-Seq preprocessing data, BMC bioinformatics, 2020, 21(16): 1-9. Yating He, Haihua Zhang, Tao Wang, Zhifa Han, Qing-bin Ni, Kun Wang, Longcai Wang, Yan Zhang, Yang Hu, Shuilin Jin, Bao-liang Sun, Guiyou Liu. Impact of serum calcium levels on Alzheimer’s disease: a Mendelian randomization study, Journal of Alzheimer's Disease, 2020, 76(2): 713-724. Longcai Wang, Yanchun Qiao, Haihua Zhang, Yan Zhang, Jiao Hua, Shuilin Jin, Guiyou Liu. Circulating vitamin D levels and Alzheimer’s disease: a Mendelian randomization study in the IGAP and UK Biobank, Journal of Alzheimer's Disease, 2020, 73(2): 609-618. 2019 Guiyou Liu, Yang Hu, Zhifa Han, Shuilin Jin*, Qinghua Jiang*. Genetic variant rs17185536 SIM1 gene expression in human brain hypothalamus, Proceedings of the National Academy of Sciences: PNAS, 2019, 116 (9): 3347-3348. Zhuo Wang, Shuilin Jin*, Chiping Zhang*, A method based on differential entropy-like function for detecting differentially expressed genes across multiple conditions in RNA-Seq studies, Entropy, 2019, 21(3): 242. Nan Wang, Ying Zhang, Li Xu, Shuilin Jin*, Relationship between Alzheimer's disease and the immune system: A meta-analysis of differentially expressed genes, Frontiers in Neuroscience, 2019, 12: 1026. 2018 Zhifa Han, Rui Tian, Peng Ren, Wenyang Zhou, Peng Wang, Shuilin Jin*, Qinghua Jiang*, Parkinson's disease and Alzheimer's disease: a Mendelian randomization study, BMC medical genetics, 2018, 19 (1), 215 Guiyou Liu, Shuilin Jin, Yang Hu, Qinghua Jiang*. Disease status affects the association between rs4813620 and the expression of Alzheimers disease susceptibility gene TRIB3. PNAS, 115(45), E10519-E10520 Zhifa Han#, Tao Wang#, Rui Tian, Wenyang Zhou, Pingping Wang, Peng Ren, Jian Zong, Yang Hu, Shuilin Jin*, Qinghua Jiang*. BIN1 rs744373 variant is significantly associated with Alzheimer’s disease in Caucasian but not East Asian populations. 2018. BMC Bioinformatics. (Accepted) Weiyue Ding, Li Xu, Lejun Zhang, Zhijie Han, Qinghua Jiang, Z Wang, Shuilin Jin*, Meta-analysis of association between TCF7L2 polymorphism rs7903146 and type 2 diabetes mellitus, BMC medical genetics, 19 (1), 38 Guiyou Liu, Y Zhao, Shuilin Jin, Yang Hu, Tao Wang, Rrui Tian, Zhifa Han, D Xu, Qinghua Jiang, Circulating vitamin E levels and Alzheimer’s disease: a Mendelian randomization study, Neurobiology of aging, 2018 Guiyou Liu, Tao Wang, Rrui Tian, Yang Hu, Zhifa Han, P Wang, W Zhou, P Ren, J Zong, Shuiiln Jin*, Qinghua Jiang*, Alzheimer’s Disease Risk Variant rs2373115 Regulates GAB2 and NARS2 Expression in Human Brain Tissues, Journal of Molecular Neuroscience, 2018, 1-7 2017 Yang Hu, Shuilin Jin, Liang Cheng, Guiyou Liu, and Qinghua Jiang Autoimmune disease variants regulate GSDMB gene expression in human immune cells and whole blood, Proceedings of the National Academy of Sciences of the United States of America: PNAS, 2017.Zhuo Wang*, Shuilin Jin*, Guiyou Liu, Xiurui Zhang, Nan Wang, Deliang Wu, Yang Hu, Chiping Zhang*, Qinghua Jiang, Li Xu, Yadong Wang*, DTWscore:differential expression and cell clustering analysis for time-series single-cell RNA-seq data, BMC Bioinformatics, 2017, 18:270. Guiyou Liu, Yang Hu, Shuilin Jin, Qinghua Jiang*, Genetic variant rs763361 regulates multiple sclerosis CD226 gene expression, Proceedings of the National Academy of Sciences of the United States of America: PNAS, 2017, 114(6): E906-E907. Jan Hamhalter, Shuilin Jin*, Operationalindependence and tensor products of C*-algebras, Journal of Mathematical Physics, 2017, 58(3):032303. Jiajie Peng, Kun Bai, Xuequn Shang, Guohua Wang, Hansheng Xue, Shuilin Jin, Liang Cheng, Yadong Wang, Jin Chen,Predicting disease-related genes using integrated biomedical networks, BMC Genomics, 2017, 18(Suppl 1): 1043. Yang Hu, Likun Zheng, Liang Cheng, Ying Zhang, Weiyang Bai, Wenyang Zhou, Tao Wang, Zhifa Han, Jian Zong, Shuilin Jin, Jun Zhang, Guiyou Liu, Qinghua Jiang, GAB2 rs2373115 variant contributes to Alzheimer@#%s disease risk specifically in European population, Journal of the Neurological Sciences, 2017, 375: 18-22. 2016 Shuilin Jin, et al. The complexity of promoter regions based on a vector topological entropy. Current Bioinformatics, Volume 11. Yang Hu, Zhou W, Ren J, Dong L, Wang Y, Shuilin Jin*, Cheng L.Annotating the Function of the Human Genome with Gene Ontology and Disease Ontology. Biomed Res Int. 2016;2016:4130861. Qinghua Jiang*, Shuilin Jin*, Yongshuai Jiang, Mingzhi Liao, Rennan Feng, Liangcai Zhang, Guiyou Liu, Junwei Hao. Alzheimer@#%s disease variants with the genome-wide significance are significantly enriched in immune pathways and active in immune cells,Molecular Neurobiology, 09 January, 1-7. Guiyou Liu, Yang Hu, Shuilin Jin, Fang Zhang, Qinghua Jiang, Junwei Hao. Cis-eQTLs regulate reduced LST1 gene and NCR3 gene expression and contribute to increased autoimmune disease risk. PNAS. 113, 42, E6321–E6322. Guoqiang Wan, Wenyang Zhou, Yang Hu, Rui Ma, Shuilin Jin, Guiyou Liu, and Qinghua Jiang. Transcriptional Regulation of lncRNA Genes by Histone Modification in Alzheimer’s Disease. 2016 (2016), 3164238. Wanqian Guo, Zizeng Yang, Juanshan Du, Renli Yin, Xianjiao Zhou, Shuilin Jin and Nanqi Ren. Degradation of sulfadiazine in water by a UV/O3 process: performance and degradation pathway. RSC Adv., 2016,6, 57138-57143 2015 Qinghua Jiang,Jixuan Wang,Xiaoliang Wu,Rui Ma,Tianjiao Zhang,Shuilin Jin, Zhijie Han, Renjie Tan, Jiajie Peng, Guiyou Liu, Yu Li, Yadong Wang. LncRNA2Target: a database for differentially expressed genes after lncRNA knockdown or overexpression，Nucleic Acids Research,2015, 43(D1):D193-D196. Qinghua Jiang,Rui Ma,Jixuan Wang,Xiaoliang Wu,Shuilin Jin,Jiajie Peng, Renjie Tan, Tianjiao Zhang, Yu Li, Yadong Wang, LncRNA2Function: A comprehensive resource for functional investigation of human lncRNAs based on RNA-seq data, BMC Genomics, 2015, 16：S2. 2014 Li Xu，Shuilin Jin，Guisheng Yin, A track association algorithm based on the weighted association graph for laser triangulation sensors, Optik, 2014, 125(20): 5973-5977. Li Xu，Shuilin Jin，Guisheng Yin，A track association algorithm based on leader-follower on-line clustering in dense target environments, Radioengineering, 2014, 23(1):259-265. Li Xu, Shuilin Jin, Guisheng Yin,Bidirectional-paralleled flexible graphplan, Journal of Computational and Theoretical Nanoscience, 2014, 11(10):2190-2193. 2013 Shuilin Jin and Li Xu. Independences of operator algebras and joint spectrum of operators. Linear and Multilinear Algebra. 2013, 61(5): 565-572. Qinghua Jiang, Guohua Wang, Shuilin Jin, Yu Li, Yadong Wang Predicting human microRNA-disease associations based on support vector machine, International Journal of Data Mining and Bioinformatics. 2013, 8(3): 282-293. Shuilin Jin and Li Xu. On Curto’s open problem. Journal of Mathematical Analysis and Applications. 2013, 1(405): 342-344. Shuilin Jin, Li Xu and Qinghua Jiang. Joint spectrum and joint distribution. Complex Analysis and Operator Theory. 2013, 7: 1869-1875. Li Li, Shuilin Jin and Li Yang. Large time behavior of the Vlasov-Poisson-Boltzmann system. Abstract and Applied Analysis. 2013, 2013: 632903. Li Xu, Shuilin Jin and Guisheng Yin. Track fusion via track filter in dense sensor environments. Measurement. 2013, 46(10): 3871-3875. 2012 Shuilin Jin, Li Xu, Qinghua Jiang and Li Li. Conditions equivalent to C* independence Studia Mathematica. 2012, 211(3):191-197. Shuilin Jin and Li Xu. The entanglement of independent quantum systems. Advances in Mathematical Physics. 2012, 2012: 104856. Shuilin Jin, Qinghua Jiang, Yadong Wang and Guangren Duan. On joint spectrum of infinite direct sums. Operators and Matrices. 2012, 6(3): 529-533. Shuilin Jin, Li Xu, Qinghua Jiang and Guangren Duan. A joint spectral characterization of C* independence. Infinite Dimensional Analysis Quantum Probability and Related Topics. 2012, 15(2): 1250013.