吴彦超

基本信息 科学研究 教学 论文论著/Publication 实验室仪器设备 新建主栏目 基本信息 名称 吴彦超，汉族，哈尔滨工业大学博士生导师、哈尔滨工业大学（威海）学科带头人，天然产物与药物合成化学。主持国家自然科学基金、北京分子科学国家实验室基金、省重点研发项目、省自然科学基金项目等。发表学术论文论著190多篇，书籍章节10多部。入选泰山产业领军人才，担任山东省海洋船舶防污工程技术研究中心副主任、山东省青年创新人才协会理事、威海市海产品活性因子重点实验室主任，《Marine Science and Research》/《海洋科学与研究》、《Ocean Journal of Biotechnology and Bioengineering》/《海洋生物技术与生物工程杂志》 和 《Journal of Medicines Development Sciences》/《药物开发科学杂志》三个期刊的编委。 我的新闻 荣誉称号 名称 2021年 山东省大学生科技创新大赛优秀指导教师 2021年 “挑战杯”山东省大学生课外学术科技作品竞赛优秀指导教师 2021年 威海市自然科学优秀学术成果奖 2019年 校长杯创新创业竞赛优秀作品特等奖指导教师 2019年 哈尔滨工业大学优秀思想政治工作者 2019年 校级学生活动优秀指导教师 2018年 金烛奖优秀班主任 2018年 泉城特聘专家 2017年 山东省大学生科技创新大赛优秀指导教师 2017年 泰山产业领军人才 2015年 校级优秀研究生指导老师 2012年 校级科研先进个人奖 2004年 中国科学院化学研究所青年科学特别奖 2003年 中国科学院化学研究所青年科学优秀奖 2002年 南开大学杨石先奖 工作经历 名称 时间 工作经历 2011年-至今 哈尔滨工业大学（威海）海洋科学与技术学院，天然产物化学，教授 2006年-2011年 法国国家科学研究中心天然产物研究所，天然产物全合成，CDD chercheur 教育经历 名称 2005年，中国科学院化学研究所，分子识别与功能重点实验室，有机化学，理学博士 主要任职 名称 2022年 威海市海产品活性因子重点实验室主任 2022年 Marine Science and Research 编委 2021年 Ocean Journal of Biotechnology and Bioengineering 编委 2018年 Journal of Medicines Development Sciences 编委 2017年 山东省青年创新人才协会理事 2017年 哈尔滨工业大学优秀专兼职学生工作者 2015年 哈尔滨工业大学优秀专兼职学生工作者 2011年 山东省海洋船舶防污工程技术研究中心副主任 2011年 ACS, RSC, Wiley, Springer 等数据库期刊审稿人 研究领域 名称 （海洋）天然产物合成 海洋环境中的材料防护 有机化学 药物化学 研究方向：挑战合成化学极限造福人类生活是我们的目标。课题组从事天然产物合成、药物合成、金属腐蚀防护、防海洋生物附着等有机化学领域的基础研究及相关产品研发。 团队成员 名称 吴彦超教授、李惠静教授、刘卫副教授、王俊沪副教授、刘颖工程师、公丕贤讲师、徐广森讲师等。 科研项目 名称 国家自然科学基金22271070，原花青素类功能化合物的合成及应用研究，参与 国家自然科学基金21672046，基于重排反应策略的若干海洋萜类天然产物的手性全合成，主持 国家自然科学基金21272046，基于有机SOMO活化串联环化反应的几种多环萜类天然产物的不对称全合成研究，主持 山东省重点研发项目 (乡村振兴科技创新提振行动计划) 2022TZXD0034，西洋参产业关键技术创新及应用示范，参与 国家重点研发计划2017YFB0307700，新型氟硅材料制备关键技术，参与 北京分子科学国家实验室基金，壳聚糖两性离子高分子功能材料的合成研究，主持 天然药物及仿生药物国家重点实验室基金K20120210，嘌酮菌素天然产物全合成研究，主持 山东省自然科学基金ZR2020MB009，海洋天然产物的全合成研究，主持 山东省自然科学基金ZR2012BM002，Puupehenone类海洋天然产物的全合成，主持 山东省重点研发项目2019GSF108089，基于海洋天然产物pelorol的抗白血病药物开发，主持 国家自然科学基金20472087, 具有芳香性的alpha-和beta-氨基酸的不对称合成，参与 国家自然科学基金重点项目20232010，金属促进的非活性化学键的选择性切断与应用，参与 国家自然科学基金20172023，基于药效团模型的新型除草剂的设计、合成及生物活性研究，参与 讲授课程 名称 《有机波谱分析》、《药物合成》、《化学工程与工艺专业导论》 简介：本科生课程 《有机波谱分析》、《海洋化学讲座》 简介：研究生课程 招生信息 名称 硕士招生: 海洋科学/应用化学 2～4名/年，有机化学、天然产物化学、防腐防污材料化学 博士招生: 海洋科学/应用化学 1～2名/年，有机化学、天然产物化学、防腐防污材料化学 Publication 名称 Books/Chapters Li Hui-Jing*, Zhang Weiwei, Wu Yan-Chao, “Chapter 5-Anti-corrosion properties of alkaloids on metals” in Alkaloids-Their Importance in Nature and Human Life (ISBN 978-1-78984-692-8), Editor: Joanna Kurek, Publisher: IntechOpen, United Kingdom, 2018, 1, 73-87. Wu Yan-Chao*, Cheng Yun-Fei, Li Hui-Jing, “Chapter 4-Approaches to the total synthesis of puupehenone-type marine natural products (海洋天然产物)” in Organic Synthesis-A Nascent Relook (ISBN 978-1-83880-626-2), Editor: Belakatte Parameshwarappa Nandeshwarappa, Publisher: IntechOpen, London, United Kingdom, 2019, 1, 51-69. Wu Yan-Chao, Wang Xiao-Bo, Li Hui-Jing, “Chapter 63-Marine natural pigments (海洋天然色素): Bioactivities, production and application” in Encyclopedia of Marine Biotechnology (海洋生物技术百科全书，ISBN 978-1-119-14377-2), Editor: Kim Se-Kwon, Publisher: John Wiley & Sons Ltd, USA, 2020, 3, 1493-1520. Lu Wen-Yu, Li Hui-Jing, Wu Yan-Chao, “Chapter 4-Marine polysaccharides from algae (海藻多糖)-Bioactivities and application in drug research” in Marine Biochemistry (海洋生物化学, ISBN 978-1-003-30391-6), Editor: Kim Se-Kwon, Publisher: CRC Press, Inc., United States, 2022, 1, 85-109. Liu Wei, Li Hui-Jing*, Wu Yan-Chao, “Chapter 1-Alginate (海藻酸盐) properties and applications” in Properties and applications of alginate (海藻酸盐, ISBN 979-8-88697-371-6), Editor: Michael Y. Wilkerson, Publisher: Nova Science Publishers, Inc., United States, 2022, 1, 1-40. 胡支江, 吴彦超, 有机化学 (ISBN 978-7-5165-2425-1), 航空工业出版社, 2022, 1, 1-313. 贾长青, 吴彦超, 天然产物化学合成策略与结构修饰研究 (ISBN 978-7-5221-1478-1), 中国原子能出版社, 2022, 1, 1-326. Wang Dan-Yang, Li Hui-Jing, Wu Yan-Chao,“Chapter 12-Grafted pectin as sustainable corrosion inhibitors” in Grafted biopolymers as corrosion inhibitors: Safety, sustainability, and efficiency (ISBN 978-1-119-88136-0), Editors: Aslam Jeenat, Verma Chandrabhan, Aslam Ruby, Publisher: John Wiley & Sons Ltd, 2023, Part 3, 269-283. Huang Li, Li Hui-Jing, Wu Yan-Chao*, "Chapter 3-Chemical constituents and synthetic methods of bioactive coumarins" in The Chemistry of Coumarin (ISBN 979-8-88697-560-4), Editor: Sheley Scott R., Publisher: Nova Science Publishers, Inc., United States, 2023, 23-75. Huang Li, Li Hui-Jing, Wu Yan-Chao*, "Chapter 3-Ginsenosides: Health benefits and role in disease prevention" in Advances in Health and Disease (ISBN 979-8-88697-469-0), Editor: Duncan Lowell T., Publisher: Nova Science Publishers, Inc., United States, 2023, 62, 109-151. Sheng Miao-Qing, Zhang Wei-Wei, Li Hui-Jing, Wu Yan-Chao, "Chapter 2-Traditional and eco-friendly antiscalants: Advantages and disadvantages" in Industrial scale inhibition: Principles, design, and applications (ISBN 978-1-39419-117-8), Editors: Chandrabhan Verma, Ibrahim Yahia Yaagoob, Publisher: John Wiley & Sons Inc.: Hoboken, New Jersey, U.S. 2024, Chapter 2. Liu Ying, Chen Feiyu, Wang Zhou, Li Hui-Jing, Wu Yan-Chao, "Chapter 9-Organic compounds as scale inhibitors" in Industrial scale inhibition: Principles, design, and applications (ISBN 978-1-39419-117-8), Editors: Chandrabhan Verma, Ibrahim Yahia Yaagoob, Publisher: John Wiley & Sons Inc.: Hoboken, New Jersey, U.S. 2024, Chapter 9. Cui Yong-Yin, Gong Pi-Xian, Li Hui-Jing, Wu Yan-Chao, "Chapter 10-Plant extracts as scale inhibitors" in Industrial scale inhibition: Principles, design, and applications (ISBN 978-1-39419-117-8), Editors: Chandrabhan Verma, Ibrahim Yahia Yaagoob, Publisher: John Wiley & Sons Inc.: Hoboken, New Jersey, U.S. 2024, Chapter 10. Cui Yong-Yin, Xu Guang-Sen, Li Hui-Jing, Wu Yan-Chao, "Chapter 13-Copolymers and polymers as scale inhibitors" in Industrial scale inhibition: Principles, design, and applications (ISBN 978-1-39419-117-8), Editors: Chandrabhan Verma, Ibrahim Yahia Yaagoob, Publisher: John Wiley & Sons Inc.: Hoboken, New Jersey, U.S. 2024, Chapter 13. Li Hao-Ran, Liu Wei, Wu Yan-Chao, Li Hui-Jing, "Chapter 19-Sustainable corrosion inhibition in neutral sodium chloride solutions using phytochemicals/plant extracts" in Phytochemistry in corrosion science: Plant extracts & phytochemicals as corrosion inhibitors, Editors: Chandrabhan Verma, Ashish Kumar, Abhinay Thakur, Publisher: Chemical Rubber Company (CRC); Taylor and Francis Group, Headquarters: Boca Raton, Florida, USA, 2024, Chapter 19.Papers Wu Yue-Cheng, Xu Guang-Sen, Li Hui-Jing, Wu Yan-Chao*, Stereoselective synthesis of xylodonin A and 22-hydroxyxylodonin A and discovery of analogues with cytotoxic activity, J. Nat. Prod., 2024, 87 (4), 884-892 (中科院1区期刊、TOP期刊, IF = 5.1). Published as part of Journal of Medicinal Chemistry virtual special issue “Natural Products Driven Medicinal Chemistry”. Fu Ze, Ju Hao, Xu Guang-Sen*, Wu Yan-Chao, Chen Xiao, Li Hui-Jing*, A comprehensive review of strategies to deliver anthocyanin by micro/nanoparticle, Food Chem., 2024, 439, 138104 (中科院1区期刊、TOP期刊, IF = 8.8). Nie Boli, Zhang Weiwei*, Dou Xiangyu, Meng Yanming, Zhao Xi, Wu Yan-Chao, Li Hui-Jing*, Porous dome array evaporator for high-performance photothermal water evaporation and thermoelectric power generation, J. Mater. Chem. A, 2024, 12 (1), 293-302 (JCR1区期刊、TOP期刊, IF = 11.9). Chen Xiao, Wang Zi-Xuan, Liu Wei*, Wu Yan-Chao, Li Hui-Jing*, Understanding the nanostructures of prolamin-based oral carrier to deliver functional compounds: A review, Trends Food Sci. Tech., 2024, in revision (中科院1区期刊、TOP期刊, IF = 15.3). Lu Wen-Yu, Li Hui-Jing, Wu Yan-Chao*, Mitochondria-targeted red/near-infrared fluorescent probes for specific recognition of biothiols, Environ. Chem. Lett., 2024, in revision (JCR 1区期刊、TOP期刊, IF = 15.7). Chen Xiao, Wang Zi-Xuan, Zhang Yi, Liu Wei*, Zhao Hao-Song, Wu Yan-Chao, Li Hui-Jing*, Caseinate vs bovine serum albumin on stabilizing zein nanoparticles for co-entrapping quercetin and curcumin,Colloid. Surface. A, 2024, 683, 133041 (IF = 5.2). Chen Xiao, Qin Hao, Zhai Jia-Ming, Wang Jun-Hu*, Zhang Yu-He, Chen Yang, Wu Yan-Chao, Li Hui-Jing*, Co-encapsulation of curcumin and anthocyanins in bovine serum album-fucoidan nanocomplex with a two-step pH-driven method, J. Sci. Food Agr., 2024, 104 (5), 3100-3112 (JCR1区期刊, IF = 4.1). Huang Li, Wang Zi-Ming, Zhao Qin*, Li Hui-Jing, Wu Yan-Chao*, Chemical constituents from Uncaria laevigata and their anti-inflammatory activities and action mechanism, Nat. Prod. Res., 2024, DOI: 10.1080/14786419.2023.2301470. Huang Li, Wang Zi-Ming, Zhao Qin*, Li Hui-Jing, Wu Yan-Chao*, Chemical constituents from Uncaria laevigata and their vasodilatory activities and action mechanism, Nat. Prod. Res., 2024, DOI: 10.1080/14786419.2024.2352871. 边雅静, 于充, 刘卫*, 陈晓, 吴彦超, 李惠静*, 桦褐孔菌多糖的化学结构、生物活性及其作用机制研究进展, 食品研究与开发, 2024, accepted. 赖薪宇, 段苯莎, 吴大刚, 吴彦超, 刘卫*, 李惠静*. 葵花盘活性成分及药理作用研究进展. 中药药理与临床, 2024, DOI: 10.13412/J.CNKI.ZYYL.20230615.004. Cui Yong-Yin, Sheng Miao-Qing, Liu Ying*, Feng Yuan, Li Hui-Jing, Wu Yan-Chao*, Antifouling and self-healing performance of marine coating based on hydrogen-bond interactions, ACS Appl. Mater. Interfaces, 2023, 15 (50), 58967-58975 (JCR 1区期刊、TOP期刊, IF = 9.5). Wu Yue-Cheng, Xu Guang-Sen, Li Hui-Jing, Bian Ya-Jing, Qi Zhong-Quan, Wu Yan-Chao*, Divergent and stereoselective synthesis of ustusal A, (-)-albrassitriol and elegansin D, J. Org. Chem., 2023, 88 (23), 16511-16519 (JCR 1区期刊, IF = 3.6). Ju Hao, Yu Chong, Zhang Xian-Dong, Liu Wei, Wu Yan-Chao, Gong Pi-Xian, Li Hai-Huang, Liu Yang, Li Hui-Jing*, Anticancer activities and mechanisms of water-soluble plant polysaccharides: A review, Carbohyd. Polym. Technol. Appl., 2023, 6, 100341 (JCR 1区期刊, IF = 5.5). Gong Pi-Xian, Zong Wan-Li, Ju Hao, Wu Yan-Chao*, Li Hai-Huang, Fan Zi-Wei, Ma Chao, Liu Wei, Li Hui-Jing*, Comprehensive analysis of different types of ginsenosides in the different parts of American ginseng by targeted and nontargeted MS/MS scanning, J. Food Sci., 2023, 88 (12), 5063-5077 (IF = 3.9). Liang Junxiu, Liu Ya-Zhou, Wang, Amu, Wu Yanchao, Ma Xiaofeng*, Li Huijing*, Dearomatization of halonaphthols via an intermolecular [4+1] spiroannulation with in situ formed aza-ortho-quinone methides, Chin. J. Org. Chem., 2023, 43 (11), 3888-3899. Chen Xiao, Wu Yan-Chao, Qian Liu-Hong, Zhang Yu-He, Gong Pi-Xian, Li Hui-Jing*, Fabrication of foxtail millet prolamin/caseinate/chitosan hydrochloride composite nanoparticles using antisolvent and pH-driven methods for curcumin delivery, Food Chem., 2023, 404, 134604 (中科院1区期刊、TOP期刊, IF = 8.8) (该篇论文入选SCI数据库高被引论文). Huang Li, Li Hui-Jing, Wu Yan-Chao*, Processing technologies, phytochemistries, bioactivities and applications of black ginseng-a novel manufactured ginseng product: A comprehensive review, Food Chem., 2023, 407, 134714 (中科院1区期刊、TOP期刊, IF = 8.8). Huang Li, Liu Ying, Wang Zi-Ming, Lu Wen-Yu, Li Xin-Yue, Li Hui-Jing, Wu Yan-Chao*, Exploration of procyanidin C1 from Uncaria laevigata as a green corrosion inhibitor in industry: Electrochemical assessment, theoretical simulation, and environmental safety, Sep. Purif. Technol., 2023, 318, 123950 (中科院1区期刊、TOP期刊, IF = 8.6). Chen Xiao, Yu Chong, Zhang Yi, Wu Yan-Chao*, Yang Yan-Li, Ma Yao, Li Hui-Jing*, Co-encapsulation of curcumin and resveratrol in zein-bovine serum albumin nanoparticles using a pH-driven method, Food Funct., 2023, 14 (7), 3169-3178 (中科院1区期刊、TOP期刊, IF = 6.1). Nie Boli, Yan Junfeng*, Shi Shuanghao, Wang Li-Juan*, Wu Yan-Chao, Li Hui-Jing*, Sustainable corrosion resistance of piroxicam-cyclodextrin inclusion complex to mild steel and its mechanism, J. Mater. Res. Technol., 2023, 23, 3665-3675 (中科院1区期刊、TOP期刊, IF = 6.4). Su Xin*, Xu Ying, Wu Yanchao, Li Huijing, Yang Jianzhong*, Liao Ying, Qu Renjie, Zhang Zhengcheng*, Liquid electrolytes for low-temperature lithium batteries: Main limitations, current advances, and future perspectives, Energy Storage Mater., 2023, 56, 642-663 (中科院1区期刊、TOP期刊, IF = 20.4). Li Jianing, Yang Jianzhong, Ji Zhaoqi, Su Min, Li Huijing, Wu Yanchao, Su Xin*, Zhang Zhengcheng*, Prospective application, mechanism, and deficiency of lithium bis(oxalato)borate as the electrolyte additive for LIB, Adv. Energy Mater., 2023, 13 (35), 2301422 (中科院1区期刊、TOP期刊, IF = 27.8). Huang Li, Li Hui-Jing, Wu Yan-Chao*, A comprehensive evaluation of corrosion inhibition performance and ecotoxicological effect of cinchona IIa as a green corrosion inhibitor for pickling of Q235 steel, J. Environ. Manage., 2023, 335, 117531 (JCR 1区期刊、TOP期刊, IF = 8.3). Ju Hao, Yu Chong, Liu Wei, Li Hai-Huang, Fu Ze, Wu Yan-Chao, Gong Pi-Xian, Li Hui-Jing*, Polysaccharides from marine resources exhibit great potential in the treatment of tumor: A review, Carbohyd. Polym. Technol. Appl., 2023, 5, 100308 (JCR 1区期刊, IF = 5.5). Yu Chong, Shan Jingyu, Ju Hao, Chen Xiao, Xu Gangsen, Wu Yanchao*, Construction of a ternary composite colloidal structure of zein/soy protein isolate/sodium carboxymethyl cellulose to deliver curcumin and improve its bioavailability, Foods, 2023, 12 (14), 2692 (JCR 1区期刊, IF = 5.2). Yu Chong, Shan Jingyu, Fu Ze, Ju Hao, Chen Xiao, Xu Gangsen, Liu Yang, Li Huijing, Wu Yanchao*, Co-encapsulation of curcumin and diosmetin in nanoparticles formed by plant protein interaction using pH-driven method, Foods, 2023, 12 (15), 2861 (JCR 1区期刊, IF = 5.2). Chen Xiao, Yu Chong, Wang Jun-Hu, Wu Yan-Chao*, Ma Yao, Li Hui-Jing*, Fabrication of curcumin-loaded foxtail millet-based prolamin nanoparticle: Impact of curdlan sulfate on the particle properties, Colloid. Surface. A, 2023, 674, 131893 (IF = 5.2). Nan Xiang, Li Xin, Wu Yanchao*, Li Huijing, Wang Qiuxu*, Xing Shaojun, Liang Zhigang*, Design, synthesis and biological evaluation of sulfonylamidine derivatives as potent c-Met kinase inhibitors for cancer treatment by enhancing hydrophobic interaction, Org. Biomol. Chem., 2023, 21 (36), 7459-7466 (IF = 3.2). Cheng Yun-Fei, Li Hui-Jing, Wang Xiao-Bo, Wu Yan-Chao*, Concise synthesis of marine natural product (海洋天然产物) smenodiol and (-)-pelorol, Nat. Prod. Res., 2023, 37 (9), 1505-1510. Cheng Yun-Fei, Li Hui-Jing, Zhang Yin-Lin, Wu Yan-Chao*, A concise synthesis of marine natural product (海洋天然产物) 15-oxopuupehenol from (+)-sclarelide, Nat. Prod. Res., 2023, 37 (8), 1265-1270. 杨艳丽, 马耀, 李惠静, 吴彦超*, 有机化合物氟化反应的研究进展, 化学研究与应用, 2023, 35 (1), 10-20. Wang Xiao-Bo, Li Hui-Jing*, Li Qinghao, Ding Yufan, Hu Chenxi, Wu Yan-Chao, A specifically triggered turn-on fluorescent sensor platform and its visual imaging of HClO in cells, arthritis and tumors, J. Hazard. Mater., 2022, 427, 127874 (中科院1区期刊、TOP期刊, IF = 13.6). Gong Pi-Xian, Wu Yan-Chao, Chen Xiao, Zhou Ze-Lin, Chen Xi, Lv Shi-Zhong, You Yue, Li Hui-Jing*, Immunological effect of fucosylated chondroitin sulfate and its oligomers from Holothuria fuscogilva (海参) on RAW 264.7 cells, Carbohyd. Polym., 2022, 287, 119362 (中科院1区期刊、TOP期刊, IF = 11.2). Chen Xiao, Zhang Tong-Yu, Wu Yan-Chao*, Gong Pi-Xian, Li Hui-Jing*, Foxtail millet prolamin as an effective encapsulant deliver curcumin by fabricating caseinate stabilized composite nanoparticles, Food Chem., 2022, 367, 130764 (中科院1区期刊、TOP期刊, IF = 8.8). Chen Xiao, Wu Yan-Chao, Gong Pi-Xian, Li Hui-Jing*, Co-assembly of foxtail millet prolamin-lecithin/alginate sodium (海藻酸钠) in citric acid-potassium phosphate buffer for delivery of quercetin, Food Chem., 2022, 381, 132268 (中科院1区期刊、TOP期刊, IF = 8.8). Wang Dan-Yang, Li Zhi-Guo, Liu Ying*, Li Hui-Jing, Wu Yan-Chao*, Investigation of efficient corrosion inhibitor during acid cleaning of Reverse Osmosis (RO) desalination plant, Corros. Sci., 2022, 208, 110609 (中科院1区期刊、TOP期刊, IF = 8.3). Huang Li, Wang Zi-Ming, Wang Shan-Shan, Wang Yu-Han, Li Hui-Jing, Wu Yan-Chao*, Environmentally benign cinchonain IIa from Uncaria laevigata for corrosion inhibition of Q235 steel in HCl corrosive medium: Experimental and theoretical investigations, Environ. Res., 2022, 215, 114376 (中科院1区期刊、TOP期刊, IF = 8.3). Gong Pi-Xian, Wu Yan-Chao, Liu Ying*, Lv Shi-Zhong, You Yue, Zhou Ze-Lin, Chen Xi, Li Hui-Jing*, Structure and hypoglycemic effect of a neutral polysaccharide isolated from sea cucumber (海参) Stichopus japonicus, Int. J. Biol. Macromol., 2022, 216, 14-23 (中科院1区期刊、TOP期刊, IF = 8.2). Chen Xiao, Wu Yan-Chao*, Gong Pi-Xian, Zhang Yu-He, Li Hui-Jing*, Chondroitin sulfate deposited on the foxtail millet prolamin/caseinate nanoparticles to improve physicochemical properties and enhance therapeutic effect, Food Funct., 2022, 13 (9), 5343–5352 (中科院1区期刊、TOP期刊, IF = 6.1). Wang Dan-Yang, Li Hui-Jing*, Chen Xiao, Nie Bo-Li, Wu Yan-Chao*, Fabricating of grape seed proanthocyanidins loaded zein-NaCas composite nanoparticles to exert effective inhibition of Q235 steel corrosion in seawater (海水), J. Mol. Liq., 2022, 348, 118467 (中科院1区期刊、TOP期刊, IF = 6.0). Huang Li, Zhao Qing*, Li Hui-Jing, Wang Jin-Yi, Wang Xin-Yue, Wu Yan-Chao*, Investigation of adsorption and corrosion inhibition property of Hyperoside as a novel natural corrosion inhibitor for Q235 steel in HCl medium, J. Mol. Liq., 2022, 364, 120009 (中科院1区期刊、TOP期刊, IF = 6.0). Liu Ying*, Guo Xinxin, Liu Deli, Wang Yuanyuan*, Hao Lishuang, Jin Yuming, Li Hui-Jing, Wu Yan-Chao*, Inhibition effect of sparteine isomers with different stereochemical conformations on the corrosion of mild steel in hydrochloric acid solution, J. Mol. Liq., 2022, 345, 117833 (中科院1区期刊、TOP期刊, IF = 6.0). Liu Ying*, Guo Xinxin, Wang Baozheng, Gong Pi-Xian, Liu Yiping, Li Hui-Jing, Wu Yan-Chao*, Lentinan as an eco-friendly corrosion inhibitor for Q235 steel in acid medium: Experimental and theoretical studies, J. Mol. Liq., 2022, 360, 119513 (中科院1区期刊、TOP期刊, IF = 6.0). Wang Dan-Yang, Wang Jun-Hu, Li Hui-Jing, Wu Yan-Chao*, Pectin-amino acid derivatives as highly efficient green inhibitors for the corrosion of N80 steel in CO2-saturated formation water, Ind. Crop. Prod., 2022, 189, 115866 (中科院1区期刊、TOP期刊, IF = 5.9). Chen Xiao, Wu Yan-Chao, Liu Ying*, Qian Liu-Hong, Zhang Yu-He, Li Hui-Jing*, Single/co-encapsulation effect and physicochemical stability of zein and foxtail millet prolamin nanoparticles, Colloid. Surface. B, 2022, 217, 112685 (中科院1区期刊、TOP期刊, IF = 5.8). Miao Jia-Lin, Ren Jia-Qi, Li Hui-Jing, Wu Da-Gang, Wu Yan-Chao*, Mesoporous crosslinked chitosan (壳聚糖)-activated clinoptilolite biocomposite for the removal of anionic and cationic dyes, Colloid. Surface. B, 2022, 216, 112579 (中科院1区期刊、TOP期刊, IF = 5.8). Wang Xiao-Bo, Li Hui-Jing*, Liu Chang*, Lu Wen-Yu, Lu Xuhao, Wu Yan-Chao*, A water-soluble turn-on fluorescent probe for rapid discrimination and imaging of Cys/Hcy and GSH in cells and zebrafish through different fluorescent channels, Dyes Pigments, 2022, 199, 110058 (中科院1区期刊, IF = 4.5). Huang Li, Chen Wei-Qiang, Wang Shan-Shan, Zhao Qing*, Li Hui-Jing, Wu Yan-Chao*, Starch, cellulose and plant extracts as green inhibitors of metal corrosion: A review, Environ. Chem. Lett., 2022, 20 (5), 3235-3264 (JCR 1区期刊、TOP期刊, IF = 15.7). Huang Li, Wang Shan-Shan, Li Hui-Jing, Wang Jin-Yi, Li Zhi-Guo, Wu Yan-Chao*, Highly effective Q235 steel corrosion inhibition in 1M HCl solution by novel green strictosamide from Uncaria laevigata: Experimental and theoretical approaches, J. Environ. Chem. Eng., 2022, 10 (3), 107581 (JCR 1区期刊、TOP期刊, IF = 7.7). Liu Ying*, Wang Zhuo, Chen Xiao, Zhang Zhilin, Wang Baozheng, Li Hui-Jing, Wu Yan-Chao*, Synthesis and evaluation of omeprazole-based derivatives as eco-friendly corrosion inhibitors for Q235 steel in hydrochloric acid, J. Environ. Chem. Eng., 2022, 10 (6), 108674 (JCR 1区期刊、TOP期刊, IF = 7.7). Huang Li, Ren Chao, Li Hui-Jing*, Wu Yan-Chao*, Recent progress on processing technologies, chemical components and bioactivities of Chinese red ginseng, American red ginseng and Korea red ginseng, Food Bioprocess. Tech., 2022, 15 (1), 47-71 (JCR 1区期刊, IF = 5.6). Huang Li, Yang Kun-Peng, Zhao Qing*, Li Hui-Jing*, Wang Jin-Yi, Wu Yan-Chao*, Corrosion resistance and antibacterial activity of procyanidin B2 as a novel environment-friendly inhibitor for Q235 steel in 1 M HCl solution, Bioelectrochemistry, 2022, 143, 107969 (JCR 1区期刊, IF = 5.0). Cheng Yun-Fei, Li Hui-Jing, Wu Yan-Chao*, Total synthesis of marine natural products (海洋天然产物) (+)-strongylin A and corallidictyal D by regio- and stereoselective cyclization of alkenyl benzenes, J. Org. Chem., 2022, 87 (24), 16767–16775 (JCR 1区期刊, IF = 3.6). Liu Ying*, Wang Baozheng, Sui Yanze, Lei Yuzhen, Jin Yuming, Wu Yanchao*, Imidazole-thiazolo[5,4-d]thiazoles as highly efficient corrosion inhibitors for mild steel in acidic media: Experimental and theoretical investigation, J. Mater. Sci., 2022, 57 (35), 16904-16922 (IF = 4.5). Liu Ying*, Wang Zhuo, Zhang Zhengyan, Wang Yuanyuan*, Cheng Jiawei, Li Hui-Jing, Wu Yan-Chao*, Investigation of 3-(phenylsulfinyl)indoles self-assembled monolayer for the inhibition of iron corrosion in acidic media, Mater. Corros., 2022, 73, 1490-1504. Chen Xiao, Wu Yan-Chao*, Qian Liu-Hong, Zhang Yu-He, Gong Pi-Xian, Li Hui-Jing, Comparison of health-relevant polyphenolic component contentand bioavailability of bilberry (Vaccinium Myrtillus L.), blueberry (Vaccinium Sect. Cyanococcus Rydb.) and chokeberry (Aronia Melanocarpa (Michx.) Elliott), Food Sci. Eng., 2022, 3 (2), 120-127. 解丽君, 李惠静, 吴彦超*, 抗菌性碘的高分子复合物研究进展, 塑料, 2022, 51 (2), 80-84. 于立冬, 李惠静, 吴彦超*, 有机杂环缓蚀剂的研究进展, 现代化工, 2022, 42(7), 56-59. 李鑫, 李惠静, 吴彦超*, 固体二氧化氯制备研究进展, 现代化工, 2022, 42 (2), 88-90+96. Gong Pi-Xian, Li Qin-Ying, Wu Yan-Chao*, Lu Wen-Yu, Zeng Jun, Li Hui-Jing*, Structural elucidation and antidiabetic activity of fucosylated chondroitin sulfate from sea cucumber Stichopus japonicus (海参), Carbohyd. Polym., 2021, 262, 117969 (中科院1区期刊、TOP期刊, IF = 11.2). Zhang Weiwei, Nie Boli, Li Hui-Jing*, Li Qinying*, Li Chaoyi, Wu Yan-Chao*, Inhibition of mild steel corrosion in 1 M HCl by chondroitin sulfate and its synergistic effect with sodium alginate (海藻酸钠), Carbohyd. 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Wang Dan-Yang, Nie Bo-Li, Li Hui-Jing*, Zhang Wei-Wei, Wu Yan-Chao*, Anticorrosion performance of grape seed proanthocyanidins extract and Tween-80 for mild steel in hydrochloric acid medium, J. Mol. Liq., 2021, 331, 115799 (中科院1区期刊、TOP期刊, IF = 6.0). Wang Dan-Yang, Nie Bo-Li, Li Hui-Jing, Wang Fei, Zhang Wen-Zhuo, Wu Yan-Chao*, Experimental and theoretical investigation of inhibition behavior of bisflavanol for Q235 steel in hydrochloric acid solution, J. Mol. Liq., 2021, 342, 117490 (中科院1区期刊、TOP期刊, IF = 6.0). Chen Weiqiang, Liu Mei, Li Hui-Jing*, Wu Yan-Chao*, Switchable and efficient conversion of 2-amido-aryl oxazolines to quinazolin-4(3H)-ones and N-(2-chloroethyl)benzamides, Org. Chem. Front., 2021, 8 (3), 584-590 (中科院1区期刊, IF = 5.4). Chen Weiqiang, Li Hui-Jing, Liu Mei, Gong Pi-Xian, Wu Yan-Chao*, Synthesis of difluorinated 3-oxo-N,3-diarylpropanamides from 4-arylamino coumarins mediated by selectfluor, Org. Chem. Front., 2021, 8 (23), 6636-6641 (中科院1区期刊, IF = 5.4). Wang Xiao-Bo, Zhang Dalong, Li Hui-Jing*, Lu Xuhao, Liu Quanze, Wu Yan-Chao*, Rational design of an HClO-specific triggered self-immolative fluorescent turn-on sensor and its bioimaging applications, J. Mater. Chem. B, 2021, 9 (42), 8793-8800 (JCR 1区期刊, IF = 7.0). Lu Wen-Yu, Li Hui-Jing*, Li Qin-Ying, Wu Yan-Chao*, Application of marine natural products (海洋天然产物) in drug research, Bioorg. Med. Chem., 2021, 35, 116058 (JCR 1区期刊, IF = 3.5). Hu Yue, Dong Yao-Dong, Wu Yan-Chao, Wang Qiu-Xu, Nan Xiang, Wang Da-Li*, AMPK inhibitor BML-275 induces neuroprotection through decreasing cyt c and AIF expression after transient brain ischemia, Bioorg. Med. Chem., 2021, 52, 116522 (JCR 1区期刊, IF = 3.5). Zhang Weiwei, Li Hui-Jing*, Liu Ying*, Wang Danyang, Chen Liwei, Xie Lijun, Li Longyi, Zhang Wenzhuo, Wu Yan-Chao*, Stevioside-Zn2+ system as an eco-friendly corrosion inhibitor for C1020 carbon steel in hydrochloric acid solution, Colloid. Surface. A, 2021, 612, 126010 (IF = 5.2). Chen Weiqiang, Nie Boli, Liu Mei, Li Hui-Jing*, Wang Danyang, Zhang Weiwei, Wu Yan-Chao*, Mitigation effect of quinazolin-4(3H)-one derivatives on the corrosion behaviour of mild steel in HCl, Colloid. Surface. A, 2021, 627, 127188 (IF = 5.2). Chen Cai-Yang, Yu Chong, Li Hui-Jing*, Zhang Chi, Zhang Weiwei*, Wu Yan-Chao*, Adlay seed hull polysaccharide as a green corrosion inhibitor for mild steel in acid solution: Surface analyses and theoretical calculations, New J. Chem., 2021, 45 (45), 21188-21198 (IF = 3.3). Wang Hong-Shuang, Nan Xiang, Li Hui-Jing*, Cao Zhong-Yan*, Wu Yan-Chao*, A modular strategy for the synthesis of marine (海洋) originated meroterpenoid-type natural products, Org. Biomol. Chem., 2021, 19 (43), 9439-9447 (IF = 3.2). Ji Yuan-Zhao, Zhang Chi, Wang Jun-Hu*, Li Hui-Jing, Wu Yan-Chao*, Direct conversion of sulfinamides to thiosulfonates without use of additional redox agents under metal-free conditions, Org. Biomol. Chem., 2021, 19 (42), 9291-9298 (IF = 3.2). Chen Weiqiang, Li Hui-Jing*, Cheng Yun-Fei, Wu Yan-Chao*, Direct C2-arylation of N-acyl pyrroles with aryl halides under palladium catalysis, Org. Biomol. Chem., 2021, 19 (7), 1555-1564 (IF = 3.2). Li Qinying*, Zeng Jun, Gong Pixian, Wu Yanchao, Li Huijing*, Effect of steaming process on the structural characteristics and antioxidant activities of polysaccharides from Polygonatum sibiricum rhizomes, Glycoconjugate J., 2021, 38 (5), 561-572 (IF = 3.1). Chen Weiqiang, Li Chao-Yi, Li Hui-Jing*, Wu Yan-Chao*, Intermolecular amination of ketoximes with anthranils by Rh-catalyzed C–H bond activation in air, Asian J. Org. Chem., 2021, 10 (4), 838–844. Liu Ying*, Zhang Zheng-Yan, Ji Yuan-Zhao, Li Hui-Jing, Wu Yan-Chao*, Efficient synthesis of 3-(arenesulfinyl)indoles in water, Russ. J. Org. Chem., 2021, 57 (5), 831-841. 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Zhang Weiwei, Li Hui-Jing*, Chen Liwei, Sun Jiani, Ma Xingyi, Li Yunfei, Liu Chao, Han Xu, Pang Boyi, Wu Yan-Chao*, Performance and mechanism of a composite scaling–corrosion inhibitor used in seawater (海水): 10-methylacridinium iodide and sodium citrate, Desalination (脱盐), 2020, 486, 114482 (中科院1区期刊、TOP期刊, IF = 9.9). Gong Pi-Xian, Wang Bing-Kun, Wu Yan-Chao*, Li Qin-Ying, Qin Bang-Wei, Li Hui-Jing*, Release of antidiabetic peptides from Stichopus japonicas (威海刺参) by simulated gastrointestinal digestion, Food Chem., 2020, 315, 126273 (中科院1区期刊、TOP期刊, IF = 8.8). Nan Xiang, Li Hui-Jing*, Fang Sen-Biao*, Li Qin-Ying, Wu Yan-Chao*, Structure-based discovery of novel 4-(2-fluorophenoxy)quinoline derivatives as c-Met inhibitors using isocyanide-involved multicomponent reactions, Eur. J. Med. Chem., 2020, 193, 112241 (中科院1区期刊、TOP期刊, IF = 6.7). Nan Xiang, Zhang Jing, Li Hui-Jing*, Wu Rui*, Fang Sen-Biao*, Zhang Zhizhou, Wu Yan-Chao*, Design, synthesis and biological evaluation of novel N-sulfonylamidine-based derivatives as c-Met inhibitors via Cu-catalyzed three-component reaction, Eur. J. Med. Chem., 2020, 200, 112470 (中科院1区期刊、TOP期刊, IF = 6.7). Wang Xiao-Bo, Li Hui-Jing*, Chi Zhenxing, Zhao Xizheng, Wu Yan-Chao*, A novel mitochondrial-targeted two-photon fluorescent probe for the ultrafast dual channel monitoring of SO2 derivatives and its applications, Talanta, 2020, 217, 121086 (中科院1区期刊, TOP 期刊, IF = 6.1). Zhang Weiwei, Li Hui-Jing*, Li Yihao, Ma Chengshuai, Chen Liwei, Wang Lijuan*, Wu Yan-Chao*, Anticorrosion performance of acriflavine–Zn2+ system for mild steel in seawater (海水) utilization, J. Mol. Liq., 2020, 299, 112152 (中科院1区期刊, TOP 期刊, IF = 6.0). Zhang Weiwei, Chen Liwei, Wu Yan-Chao*, Chen Shengsong, Gao Yunfei, Wang Li-Juan*, Luo Yi, Li Qian, Li Hui-Jing*, Preparation of methylacridinium iodides self-assembled monolayers and its anticorrosive performance for mild steel in seawater (海水), J. Mol. Liq., 2020, 313, 113545 (中科院1区期刊, TOP 期刊, IF = 6.0). Zhang Weiwei, Ma Yao*, Chen Liwei, Wang Li-Juan*, Wu Yan-Chao, Li Hui-Jing*, Aloe polysaccharide as an eco-friendly corrosion inhibitor for mild steel in simulated acidic oilfield water, J. Mol. Liq., 2020, 307, 112950 (中科院1区期刊, TOP 期刊, IF = 6.0) Ji Yuan-Zhao, Li Hui-Jing*, Wang Yi-Ruo, Zhang Zheng-Yan, Wu Yan-Chao*, Sulfoxide-promoted chlorination of indoles with chlorine anion as nucleophile, Adv. Synth. Catal., 2020, 362 (5), 1039-1045 (JCR 1区期刊, IF = 5.4). Wang Xiao-Bo, Li Hui-Jing*, Chi Zhenxing, Zeng Xianshun*, Wang Li-Juan, Cheng Yun-Fei, Wu Yan-Chao*, A novel mitochondrial targeting fluorescent probe for ratiometric imaging SO2 derivatives in living cells, J. Photochem. Photobiol. A Chem., 2020, 390, 112339 (JCR 1区期刊, IF = 4.3). Zhang Weiwei, Liu Ying*, Zhang Yinlin, Wang Li-Juan*, Wu Yan-Chao, Li Hui-Jing*, 9-Substituted acridines as green and effective oilfield corrosion inhibitors for mild steel: electrochemical, surface morphology and quantum chemical studies, New J. Chem., 2020, 44 (16), 6464-6474 (IF = 3.3). Chen Wei-Qiang, Li Hui-Jing*, Li Qin-Ying, Wu Yan-Chao*, Direct oxidative coupling of N-acyl pyrroles with alkenes by ruthenium(II)-catalyzed regioselective C2-alkenylation, Org. Biomol. Chem., 2020, 18 (3), 500-513 (IF = 3.2). Wang Dan-Yang, Li Hui-Jing,* Huang Deng-Ming, Wu Yan-Chao,* Tin( II )-catalyzed dehydrative cross-coupling of 2H-chromene hemiacetals with ketones, Org. Biomol. Chem., 2020, 18 (45), 9308-9315 (IF = 3.2). Chen Weiqiang, Li Hui-Jing*, Lu Wen-Yu, Wu Yan-Chao*, Ruthenium(II)-catalyzed monohydroalkylation of α,β-unstaurated ketones with N-acyl pyrroles using a C–H activation strategy, Asian J. Org. 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Zhang Weiwei, Li Hui-Jing*, Wang Ankai, Ma Chengshuai, Wang Zhangxiao, Zhang Hao, Wu Yan-Chao*, Synergistic inhibition effect of N-(furan-2-ylmethyl)-7H-purin-6-amine and iodide ion for mild steel corrosion in 1 mol/L HCl, Mater. Corros., 2020, 71 (3), 498-507. Pan Qianwen, Li Huijing, Wu Yanchao*, Research progress of povidone-iodine modified antibacterial composites, Eng. Plast. Appl., 2020, 48 (6), 133-136. Zhang Weiwei, Li Hui-Jing*, Wang Meirong, Wang Li-Juan*, Pan Qianwen, Ji Xubiao, Qin Yaqian, Wu Yan-Chao*, Tetrahydroacridines as acidizing oilfield inhibitor for X80 steel corrosion in simulated acidic oilfield water: Electrochemical, surface and theoretical studies, J. Mol. Liq., 2019, 293, 111478 (中科院1区期刊, TOP 期刊, IF = 6.0). Ji Yuan-Zhao, Li Hui-Jing*, Zhang Jin-Yu, Wu Yan-Chao*, Switchable regioselection of C-H thiolation of indoles using different TMS counterions, Chem. Commun., 2019, 55 (79), 11864-11867 (JCR 1区期刊, IF = 4.9). Nan Xiang, Jiang Yi-Fan, Li Hui-Jing*, Wang Jun-Hu, Wu Yan-Chao*, Design, synthesis and evaluation of sulfonylurea-containing 4-phenoxyquinolines as highly selective c-Met kinase inhibitors, Bioorg. Med. Chem., 2019, 27 (13), 2801-2812 (JCR 1区期刊, IF = 3.5). Zhang Weiwei, Wang Yiwei, Li Hui-Jing*, Liu Yinghui, Tao Ran, Guan Shuyan, Wu Yan-Chao*, Synergistic inhibition effect of 9-(4-chlorophenyl)-1,2,3,4-tetrahydro-acridines and Tween-80 for mild steel corrosion in acid medium, J. Phys. Chem. C, 2019, 123 (23), 14480-14489 (IF = 3.7). Zhang Weiwei, Li Hui-Jing*, Wang Meirong, Wang Li-Juan*, Zhang Ai-Han, Wu Yan-Chao*, Highly effective inhibition of mild steel corrosion in HCl solution by using pyrido[1,2-a]benzimidazoles, New J. Chem., 2019, 43 (1), 413-426 (IF = 3.3). Zhang Weiwei, Li Hui-Jing*, Wang Chen, Wang Li-Juan*, Li Gen, Ma Hengyu, Pan Qianwen, Wu Yan-Chao*, Performance of 1-(2,5-dioxoimidazolidin-4-yl) urea towards corrosion mitigation of mild steel in hydrochloric acid, New J. Chem., 2019, 43 (35), 13899-13910 (IF = 3.3). Ji Yuan-Zhao, Zhang Jin-Yu, Li Hui-Jing*, Han Chunguang, Wu Yan-Chao*, Regioselective and oxidant-Free sulfinylation of indoles and pyrroles with sulfinamides, Org. Biomol. Chem., 2019, 17 (19), 4789-4800 (IF = 3.2). Ji Yuan-Zhao, Li Hui-Jing*, Zhang Jin-Yu, Wu Yan-Chao*, Sodium arenesulfinates-involved sulfinate synthesis revisited: Improved synthesis and revised reaction mechanism, Eur. J. Org. Chem., 2019, (8), 1846-1855. Huang Deng-Ming, Li Hui-Jing*, Zhao Yan, Wu Yan-Chao*, Synthesis of bisflavanol-type natural products and their analogues via self-coupling of C8-methylol catechin derivatives, Synthesis, 2019, 51 (16), 3127-3141. Chen Wei-Qiang, Zhang Yin-Lin, Li Hui-Jing*, Nan Xiang, Liu Ying, Wu Yan-Chao*, Synthesis of N-sulfonyl and N-acyl pyrroles via a RCM/dehydrogenation tandem reaction, Synthesis, 2019, 51 (19), 3651-3666. Gong Pi-Xian, Li Hui-Jing*, Wang Meirong, Cheng Yun-Fei, Wu Yan-Chao*, Synthesis of natural product inulavosin via Ga(OTf)3-catalyzed hetero Diels–Alder dimerization of salicyl alcohol derivative, Nat. Prod. Res., 2019, 33 (20), 2911-2916. Wang Hong-Shuang, Li Hui-Jing*, Wang Long-Fei, Shen Zhi-Lun, Wu Yan-Chao*, Regioselective synthesis of gentisyl alcohol-type marine natural products (海洋天然产物), Nat. Prod. Res., 2019, 33 (13), 1891-1896. Ma Lianfeng, Li Huijing, Wu Yan-Chao*,Base-promoted green synthesis of quinolinamide derivatives, Chem. Bull., 2019, 82 (6), 516-521. Gao Teng, Liu Ying*, Zhang Weiwei, Sui Yanze, Wu Yanchao*,Preparation and anticorrosion properties of polyaniline & polyaminophenol nanomaterials, Fine Chem., 2019, 36 (7), 1301-1307,1333. Wang Jun-Li, Li Hui-Jing, Wu Yan-Chao*, Divergent synthesis of marine natural products (海洋天然产物) siphonodictyal B, corallidictyals C/D and liphagal based on the early presence of an aldehyde group instead of a late-stage introduction, J. Org. Chem., 2018, 83 (15), 8716-8723 (JCR 1区期刊, IF = 3.6). Zhang Weiwei, Li Hui-Jing*, Wang Meirong, Wang Li-Juan*, Shang Fei, Wu Yan-Chao*, Halogen-substituted acridines as highly effective corrosion inhibitors for mild steel in acid medium, J. Phys. Chem. C, 2018, 122 (44), 25349-25364 (IF = 3.7). Zhang Weiwei, Li Hui-Jing*, Wang Yiwei, Liu Ying, Wu Yan-Chao*, Gravimetric, electrochemical and surface studies on the anticorrosive properties of 1-(2-pyridyl)-2-thiourea and 2-(imidazol-2-yl)- pyridine for mild steel in hydrochloric acid, New J. Chem., 2018, 42 (15), 12649-12665 (IF = 3.3). Huang Deng-Ming, Li Hui-Jing*, Wang Jun-Hu, Wu Yan-Chao*, Asymmetric total synthesis of talienbisflavan A, Org. Biomol. Chem., 2018, 16 (4), 585-592 (IF = 3.2). Zhang Weiwei, Li Hui-Jing*, Wu Yan-Chao, Luo Qi, Liu Huanhuan, Niu Lin*, Adsorption activity and molecular dynamics study on anti-corrosion mechanism of Q235 steel, Chem. Res. Chin. Univ., 2018, 34 (5), 817-822 (IF = 3.1). Wang Hong-Shuang, Li Hui-Jing*, Zhang Zhen-Guo, Wu Yan-Chao*, Divergent synthesis of bioactive marine meroterpenoids (海洋萜 ) by palladium-catalyzed tandem carbene migratory insertion, Eur. J. Org. Chem., 2018, (7), 915-925. Deng Kai, Huai Qi-Yong, Li Hui-Jing*, Wang Jun-Hu, Yang Hui-Ru, Liu Ying, Wu Yan-Chao*, Efficient synthesis of functionalized 4H-chromenes via an Fe(OTf)3-catalyzed cyclization reaction of phenols and ketones, Synthesis, 2018, 57 (7), 1482-1492. Huang Deng-Ming, Li Hui-Jing*, Wang Quanfu, Yan Peisheng, Wu Yan-Chao*, Synthesis of 2-(2H-chromenyl)-oxazoles from 2H-chromene hemiacetals by using a modified Passerini-type reaction, ChemistrySelect, 2018, 3 (33), 9658-9662. Wang Jun-Li, Li Hui-Jing*, Meirong Wang, Wang Jun-Hu, Wu Yan-Chao*, A six-step synthetic approach to marine natural product (海洋天然产物) (+)-aureol, Tetrahedron Lett., 2018, 59 (10), 945-948. Zhang Weiwei, Li Hui-Jing,* Liu Ying, Wu Yan-Chao,* Adsorption and corrosion inhibition properties of pyridine-2-aldehyde-2-quinolylhydrazone for Q235 steel in acid medium: Electrochemical, thermodynamic, and surface studies, Mater. Corros., 2018, 69 (11), 1638-1648. Zhao Yanyan, Li Huijing, Wu Qinxi, Deng Kai, Wu Yan-Chao*,Synthesis of 1,3-diphenylacetones, Chin. J. Syn. Chem., 2018, 26 (4), 245-249. Wang Tingting, Wu Yan-Chao, Li Hui-Jing*, Progress in heavy metal removal from seafood (海产品), Food Sci., 2018, 39 (19), 266-272. Wang Hong-Shuang, Li Hui-Jing*, Wang Jun-Li, Wu Yan-Chao*, Protecting- group-free synthesis of haterumadienone- and puupehenone-type marine natural products (海洋天然产物), Green Chem., 2017, 19 (5), 2140-2144 (中科院1区期刊、TOP期刊, IF = 9.8). Wang Jun-Li, Li Hui-Jing*, Wang Hong-Shuang, Wu Yan-Chao*, Regioselective 1,2-diol rearrangement by controlling the loading of BF3·Et2O and its application to the synthesis of related nor-sesquiterene- and sesquiterene-type marine natural products (海洋天然产物), Org. Lett., 2017, 19 (14), 3811-3814 (中科院1区期刊、TOP期刊, IF = 5.2). Mu Wan-Lu, Wang Meirong, Li Hui-Jing*, Huang Deng-Ming, Zhang Yi-Yun, Li Chao-Yi, Liu Ying, Wu Yan-Chao*, Palladium-catalyzed regioselective oxidative annulation of cyclohexanones and 2-aminophenyl ketones using molecular oxygen as the sole oxidant, Adv. Synth. Catal., 2017, 359 (23), 4250-4257 (JCR 1区期刊, IF = 5.4). Wang Hong-Shuang, Li Hui-Jing*, Nan Xiang, Luo Yuan-Yuan, Wu Yan-Chao*, Enantiospecific semisynthesis of puupehedione-type marine natural products (海洋天然产物), J. Org. Chem., 2017, 82 (23), 12914-12919 (JCR 1区期刊, IF = 3.6). Mu Wanlu, Li Xiaowei, Wang Longfei, Chen Yong, Wu Yanchao*, Pd-catalyzed aerobic oxidative annulation of cyclohexanones and 2-aminophenyl ketones: a direct approach to acridines, Green Energy and Sustable Development I, 2017, AIP Conf. Proc.: 020095-1-4 (SCI, WOS: 000411429200095). Mu Wanlu, Li Xiaowei, Wang Longfei, Chen Yong, Deng Kai, Wu Yanchao*,Iron(III) Trifluomethanesulfonate-catalyzed synthesis of 1,3,5-triarylbenzenes, Chin. J. Syn. Chem., 2017, 25 (12), 963-967. Ji Yuan-Zhao, Wang Meirong, Li Hui-Jing,* Liu Ying, Wu Yan-Chao,* Direct sulfination of nonactivated alcohols with arylsulfonylmethyl isocyanides, Eur. J. Org. Chem., 2016, (23), 4077-4083. Wang Qi, Wang Meirong, Li Hui-Jing, Zhu Shuai, Liu Ying*, Wu Yan-Chao*, Synthesis of quinolines via iron-catalyzed redox condensation of alcohols with 2-nitrobenzyl methyl ether/2-nitrobenzyl alcohols, Synthesis, 2016, 48 (22), 3985-3995. Deng Kai, Huai Qi-Yong, Shen Zhi-Lun, Li Hui-Jing*, Liu Chen, Wu Yan-Chao*, Rearrangement of dypnones to 1,3,5-triarylbenzenes, Org. Lett., 2015, 17 (6), 1473-1476 (中科院1区期刊、TOP期刊, IF = 5.2). Li Hui-Jing , Wang Rui, Gao Jing, Wang Yuan-Yuan, Luo Dong-Hui, Wu Yan-Chao*, Bismuth(III) bromide-catalyzed substitution of benzyl alcohols with aryl- sulfonylmethyl isocyanides: an unexpected access to sulfonates, Adv. Synth. Catal., 2015, 357 (7), 1393-1397 (JCR 1区期刊, IF = 5.4). Li Hui-Jing*, Wang Chen-Chao, Zhu Shuai, Dai Chun-Yang, Wu Yan-Chao*, Ruthenium(II)-catalyzed hydrogen transfer/annulation cascade processes between alcohols and 2-nitrobenzaldehydes, Adv. Synth. Catal., 2015, 357 (2-3), 583-588 (JCR 1区期刊, IF = 5.4). Wu Qin-Xi, Li Hui-Jing*, Wang Hong-Shuang, Zhang Zhen-Guo, Wang Chen-Chao, Wu Yan-Chao*, Catalyst-free synthesis of spiropyrazolines from chalcones and cyclic-ketone N-tosylhydrazones, Synlett, 2015, 26 (2), 243-249. Li Hui-Jing*, Luo Dong-Hui, Wu Qin-Xi, Dai Chun-Yang, Shen Zhi-Lun, Wu Yan-Chao*, Bi(OTf)3-catalyzed tandem reaction of naphthols with β,γ-unsaturated α-ketoesters. Efficient synthesis of functionalized 4H-chromenes, Chin. Chem. Lett., 2014, 25 (9), 1235-1239 (中科院1区期刊、TOP期刊, IF = 9.1). Li Hui-Jing, Wu Yan-Chao*, Dai Jian-Hong, Song Yan*, Cheng Runjiao, Qiao Yuanyuan, Regioselective electrophilic aromatic bromination: Theoretical analysis and experimental verification, Molecules, 2014, 19 (3), 3401-3416 (IF = 4.6). Li Hui-Jing*, Deng Kai, Luo Dong-Hui, Liu De-Hui, Wang Jun-Li, Lin Chun-Hua, Wu Yan-Chao*, Synthesis of functional 4H-chromenes from phenols and acetophenones under solvent- and metal-free conditions, RSC Adv., 2014, 4 (50), 26316-26324 (IF = 3.9). Li Hui-Jing*, Wu Ying-Ying, Wu Qin-Xi, Wang Rui, Dai Chun-Yang, Shen Zhi-Lun, Xie Cheng-Long, Wu Yan-Chao*, Water-promoted ortho-selective monohydroxymethylation of phenols in NaBO2 system, Org. Biomol. Chem., 2014, 12 (19), 3100-3107 (IF = 3.2). Li Hui-Jing, Wu Yan-Chao*, Dai Jian-Hong, Song Yan*, Cheng Runjiao, Qiao Yuanyuan, An "ortho effect" in electrophilic aromatic nitrations: theoretical analysis and experimental validation, J. Chin. Chem. Soc., 2014, 61 (12), 1307-1312. Li Hui-Jing*, Wang Jun-Li, Wang Rui, Luo Dong-Hui, Wu Yan-Chao*, Synthetic studies on potent marine drugs (海洋药物): Synthesis and the crystal structure of 6-tert-butyl-4-phenyl-4H-chromene-2-carboxylic acid, J. Chem., 2013, 106908 (IF = 3.0). Liu Zhe*, Wang Dong, Wu Yanchao, Chen Yongjun, Mild and efficient allylation of indoles and amides using amberlyst-15 as a recyclable heterogeneous catalyst, Synthetic Commun., 2012, 42 (12), 1813-1823. Wu Yan-Chao*, Li Hui-Jing, Liu Li, Demoulin Nicolas, Liu Zhe, Wang Dong, Chen Yong-Jun*, Hafnium triflate as an efficient catalyst for direct Friedel-Crafts reaction of chromene hemiacetals, Adv. Synth. Catal., 2011, 353 (6), 907-912 (JCR 1区期刊, IF = 5.4). Wu Yan-Chao*, Li Hui-Jing, Liu Li, Liu Zhe, Wang Dong, Chen Yong-Jun*, Cascade reaction of β,γ-unsaturated α-ketoesters with phenols in trityl chloride/TFA system. Highly selective synthesis of 4-aryl-2H-chromenes and their applications, Org. Biomol. Chem., 2011, 9 (8), 2868-2877 (IF = 3.2). Wu Yan-Chao*, Li Hui-Jing, Liu Li, Demoulin Nicolas, Liu Zhe, Wang Dong, Chen Yong-Jun*, Facile synthesis of spiropyrans from chromene hemiacetal esters and bifunctional nucleophiles, Synlett, 2011, (11), 1573-1578. Wu Yan-Chao*, Li Hui-Jing, Yang Hua-Zheng, A sensitive and highly selective fluorescent sensor for In3+, Org. Biomol. Chem., 2010, 8 (15), 3394-3397 (IF = 3.2). Wu Yan-Chao, Zhu Jieping*, Syntheses of (-)-renieramycin M and G and (-)-jorumycin, Synfacts, 2010, (4), 0386-0386. Liu Zhe, Liu Li*, Wu Yan-Chao, Wang Dong, Chen Yong-Jun, Efficient and metal-free Friedel-Crafts alkylation of indoles with allyl acetate mediated by TFE, Lett. Org. Chem., 2010, 7 (8), 666-670. Wu Yan-Chao, Zhu Jieping*, Asymmetric total syntheses of (–)-renieramycin M and G and (–)-jorumycin using aziridine as a lynchpin, Org. Lett., 2009, 11 (23), 5558-5561 (中科院1区期刊、TOP期刊, IF = 5.2). Wu Yan-Chao, Bernadat Guillaume, Couturier Cédric, Schlama Thierry, Zhu Jieping*, Synthetic studies on (–)-lemonomycin: an efficient asymmetric synthesis of lemonomycinone amide, J. Org. Chem., 2009, 74 (5), 2046-2052 (JCR 1区期刊, IF = 3.6). Wu Yan-Chao, Bernadat Guillaume, Couturier Cédric, Schlama Thierry, Zhu Jieping*, Synthesis of lemonomycinone amide, Synfacts, 2009, (10), 1070-1070. Wu Yan-Chao, Zhu Jieping*, Hf(IV)-catalyzed chemoselective thioacetalization and transthioacetalization, Synfacts, 2009, (3), 0314-0314. Wu Yan-Chao, Liron Mélanie, Zhu Jieping*, Asymmetric total synthesis of (–)-quinocarcin, J. Am. Chem. Soc., 2008, 130 (22), 7148-7152 (中科院1区期刊、TOP期刊, IF = 15.0). Wu Yan-Chao, Zhu Jieping*, Hafnium trifluoromethanesulfonate (hafnium triflate) as a highly efficient catalyst for chemoselective thioacetalization and transthioacetalization of carbonyl compounds, J. Org. Chem., 2008, 73 (23), 9522-9524 (JCR 1区期刊, IF = 3.6). Wu Yan-Chao*, Li Hui-Jing, Liu Li, Wang Dong, Yang Hua-Zheng, Chen Yong-Jun*, Efficient construction of pyrazolo[1,5-a]pyrimidine scaffold and its exploration as a new heterocyclic fluorescent platform, J. Fluoresc., 2008, 18 (2), 357-363. Wu Yan-Chao, Liron Mélanie, Zhu Jieping*, Total synthesis of (–)-quinocarcin, Synform, 2008, (09), A97-A98. Wu Yan-Chao, Liron Mélanie, Zhu Jieping*, Synthesis of (–)-quinocarcin, Synfacts, 2008, (12), 1253-1253. Wu Yan-Chao, Liu Li*, Liu Yu-Liang, Wang Dong, Chen Yong-Jun*, TFA-mediated tandem Friedel-Crafts alkylation/cyclization/hydrogen transfer process for the synthesis of flavylium compounds, J. Org. Chem., 2007, 72 (24), 9383-9386 (JCR 1区期刊, IF = 3.6). Liu Zhe, Liu Li*, Shafiq Zahid, Wu Yan-Chao, Wang Dong*, Chen Yong-Jun*, InCl3-catalyzed propargylation of indoles and phenols with propargylic acetates: application to the syntheses of benzofurans and naphthofurans, Synthesis, 2007, (13), 1961-1969. Liu Zhe, Liu Li*, Shafiq Zahid, Wu Yan-Chao, Wang Dong*, Chen Yong-Jun*, Iodine-catalyzed allylation and propargylation of indoles with allylic and propargylic acetates, Tetrahedron Lett., 2007, 48 (23), 3963-3967. Wu Yan-Chao, Liu Li, Li Hui-Jing, Wang Dong, Chen Yong-Jun*, Skraup-Doebner-Von Miller quinoline synthesis revisited: reversal of the regiochemistry for γ-aryl-β,γ-unsaturated α-ketoesters, J. Org. Chem., 2006, 71 (17), 6592-6595 (JCR 1区期刊, IF = 3.6). Wu Yan-Chao, Liu Li, Wang Dong, Chen Yong-Jun*, Efficient synthesis of 3-arylaminopyrroline-2-ones by the tandem reaction of anilines and β,γ-unsaturated α-ketoesters, J. Heterocyclic Chem., 2006, 43 (4), 949-955. Zhao Jun-Ling, Liu Li*, Zhang Hai-Bo, Wu Yan-Chao, Wang Dong*, Chen Yong-Jun*, Three-component Friedel-Crafts reaction of indoles, glyoxylate, and amine under solvent-free and catalyst-free conditions-synthesis of (3-indolyl) glycine derivatives, Synlett, 2006, (1), 96-100. Wu Yan-Chao, Chen Yong-Jun, Li Hui-Jing, Zou Xiao-Mao, Hu Fang-Zhong, Yang Hua-Zheng*, Synthesis of trifluoromethyl-promoted functional pyrazolo [1,5-a]pyrimidine and pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones, J. Fluorine Chem., 2006, 127 (3), 409-416. Zhao Jun-Ling, Liu Li*, Zhang Hai-Bo, Wu Yan-Chao, Wang Dong*, Chen Yong-Jun*, Rapid and convenient synthesis of aryl- and heteroaryl-α-hydroxy-α- trifluoromethyl acetate via Friedel–Crafts alkylation under solvent- and catalyst-free conditions, Tetrahedron Lett., 2006, 47 (15), 2511-2514. Wu Yan-Chao, Wu Chao, Zou Xiao-Mao, Hu Fang-Zhong, Yang Hua-Zheng*, Design and synthesis of novel fluorine-containing acrylates, Chin. Chem. Lett., 2005, 16 (10), 1293-1296 (中科院1区期刊、TOP期刊, IF = 9.1). Wu Yan-Chao, Zou Xiao-Mao, Hu Fang-Zhong, Yang Hua-Zheng*, Design and synthesis of novel 5-sulfoxide-substituted pyrazolo[5,1-d][1,2,3,5]tetrazin-4(3H) ones, Chin. Chem. Lett., 2005, 16 (9), 1143-1146 (中科院1区期刊、TOP期刊, IF = 9.1). Li Hui-Jing, Tian Hong-Yu, Wu Yan-Chao, Chen Yong-Jun, Liu Li, Wang Dong*, Li Chao-Jun*, Aqueous asymmetric mukaiyama aldol reaction catalyzed by chiral gallium Lewis acid with Trost-type semi-crown ligands, Adv. Synth. Catal., 2005, 347 (9), 1247-1256 (JCR 1区期刊, IF = 5.4). Wu Yan-Chao, Zou Xiao-Mao, Hu Fang-Zhong, Yang Hua-Zheng*, Design and synthesis of novel sulfone-containing pyrazolo[1,5-a]-pyrimidines and pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones, J. Heterocyclic Chem., 2005, 42 (4), 609-613. Wu Yan-Chao, Song Hai-Bin, Liu Li, Wang Dong, Chen Yong-Jun*, 3-(4-Methoxystyryl)-2H-1,4-benzoxazin-2-one, Acta. Cryst., 2005, E61, o1590-o1591. Wu Yan-Chao, Hu Fang-Zhong, Yang Hua-Zheng*, Temperature effect in the selective oxidation of pyrazole sulfide derivatives, Chem. Reagents, 2003, 25 (6), 329-331. Wu Yanchao, Hu Fangzhong, Yang Huazheng*, Research development on inhibitors of 4-hydroxyphenylpyruvate dioxygenase, Chin. J. Pestic. Sci., 2001, 3 (3), 1-10. 总体情况 名称 实验室现有面积1500多平方米，拥有美国API 3200Q Trap 液相质谱联用仪1台、美国 waters 2695 液相质谱联用仪1台、美国安捷伦7890A-5975C气相质谱联用仪2台、日本岛津高效液相色谱仪2台、半制备型高效液相色谱仪1台、全自动生物发酵双联罐1套（全自动灭菌、配置瑞士hamilton公司活体细胞检测器，用于检测发酵过程中活菌数实时变化）、全自动冻干机3台（用于不耐热成分的干燥，其中1台可满足中试规模生产）、紫外光谱仪1台、自动层析设备3套、离心机3台、粉碎机1台、灌装机1台、蒸煮机1台、全自动灭菌锅1台、零下80度超低温冰箱2台、各类低温冷却液循环泵近10台、万分之一分析天平、显微镜2台、恒温电磁搅拌器30多台、旋转蒸发仪近10台和多个先进的通风柜系统等设备设施，拥有各类标准的细胞间近150平方米，为样品检测和项目研发构建了优良的基础科研条件。实验室学生（本科生、硕士生和博士生）均有机会操作各类仪器设备，欢迎大家加盟我们实验室（实验室老师的研究方向：海洋科学、天然产物化学、有机材料化学、微生物学）。 实验室所在学校拥有二维液相色谱-线性离子阱-轨道阱质谱联用仪、核磁共振仪、红外光谱仪、紫外光谱仪、荧光光谱仪、透射电子显微镜、场发射扫描电子显微镜、钨灯丝扫描电子显微镜、光学数码显微镜、X-射线衍射分析仪、电感耦合等离子体发散光谱仪、同步热分析仪、旋光仪、离子色谱仪、三维体视显微镜、原子吸收分光光度计、光散射粒度及Zeta电位仪、实时荧光定量PCR仪、双恒电位仪、流式细胞仪等设备设施。 美国 API 3200 Trap 液相质谱联用仪 名称 用于食品、药品和环境成份的定性分析和定量分析、蛋白组学研究等 液相质谱联用仪waters 2695-2996-zq2000 名称 常规定性定量分析（先使用该设备判断结构，后根据需要做核磁表征） 美国安捷伦7890A-5975C气相质谱联用仪2台 名称 用于可挥发性物质的定性定量分析 日本岛津高效液相色谱仪 DGU-20A5R 名称 微量分析、半微量分析和常规定性分析和定量分析 日本岛津高效液相色谱仪（分析型） 名称 微量分析、半微量分析和常规定性分析和定量分析 半制备型高效液相色谱仪 名称 用于样品分离提纯、天然产物分离纯化 全自动生物发酵双联罐 名称 全自动灭菌、配置瑞士hamilton公司活体细胞检测器，用于检测发酵过程中活菌数实时变化 紫外光谱仪 名称 电化学工作站 名称 可进行循环伏安法、交流阻抗法、交流伏安法、电流滴定、电位滴定等测量。